Article
Green & Sustainable Science & Technology
L. M. S. Garcia, N. G. P. Filho, K. Chair, P. Kaur, A. S. Ramos, P. J. Zambiazi, R. F. B. De Souza, L. Otubo, A. Duong, A. O. Neto
Summary: Electrocatalytic carbon dioxide reduction reaction is an effective method to convert greenhouse gases into chemical fuels, and this study utilized a copper(II) complex supported on carbon black as a catalyst to convert CO2 into methanol using a polymeric electrolytic reactor - fuel cell type. The results showed that using 2.5% and 5% Cu complex achieved high faradaic efficiency.
MATERIALS TODAY SUSTAINABILITY
(2022)
Article
Chemistry, Physical
Xue-Ping Chang, Geng Zhao, Teng-Shuo Zhang, Bin-Bin Xie
Summary: This study systematically explores the excited-state properties and photophysics of cytosine aza-analogues (2,4-DT and 2-AT) in solution using the QM(MS-CASPT2//CASSCF)/MM approach. The nonradiative relaxation mechanisms for the photoexcited S-1(pi pi*) state decay back to the S-0 state are proposed based on computed minima, surface crossings, and excited-state decay paths in multiple states. The amination/deamination of the triazine rings can affect the excitation energies and nonradiative decay pathways, providing insights into the understanding of the photophysics of aza-nucleobases.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Somaye Karimian, Mohsen Shekouhy, Somayeh Pirhadi, Aida Iraji, Mahshid Attarroshan, Najmeh Edraki, Mehdi Khoshneviszadeh
Summary: In this study, a series of benzimidazole/1,3,5-triazine-2,4-diamine hybrid derivatives were designed and synthesized for the treatment of Alzheimer's disease. The compounds showed inhibitory activity against AChE, BuChE, and BACE1, and interacted with the active sites of AChE and BuChE. In silico analysis of the compounds' ADMET profiles indicated drug-like properties.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Luis M. S. Garcia, Priscilla J. Zambiazi, Khaoula Chair, Tuan Duy Doan, Andrezza S. Ramos, Julio Nandenha, Rodrigo F. B. De Souza, Larissa Otubo, Adam Duong, Almir O. Neto
Summary: This study investigates the ideal relationship between the nanostructure of a palladium complex and carbon to obtain a stable, conductive, and functional reagent diffusion electrode for the partial oxidation of methane to methanol. The results suggest that a 20% mass concentration of the palladium complex supported on carbon is the most active, exhibiting lower open-circuit and power density but higher efficiency in methanol production.
Article
Chemistry, Physical
Khaoula Chair, Cesar Augusto Luna Caceres, Sanil Rajak, Olivier Schott, Gustavo E. Ramirez-Caballero, Thierry Maris, Garry S. Hanan, Adam Duong
Summary: Carbon dioxide is an important trace gas in the atmosphere and its high concentration leads to serious issues. The use of solar energy for the photochemical reduction of CO2 is a promising strategy, but it faces challenges that need to be addressed for it to become a sustainable alternative for fuel and chemical generation. In this study, molecular photocatalysts were designed and demonstrated remarkable photocatalytic properties for CO2 reduction to CO. The mechanistic pathways of the reaction were investigated using a combination of structural characterization, experimental data, and density functional theory calculations.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Adela Abidi, Emmanuelle Fortin, Kariane Larocque, Mohamed Essalhi, Nour Dissem, Daniel Chartrand, Thierry Maris, Adam Duong
Summary: In this paper, a facile method was reported for synthesizing eight structurally diverse compounds 1-8 with a hydrogen bonding functional group - diaminotriazine (DAT) along with pyridine and polyether groups for 1-4 and DAT linked via C-C bond to a 2-pyridone for 5-8. The successful synthesis of 1-8 was confirmed by various analytical techniques. The molecular structures and aggregations in the solid state of these compounds were elucidated using single crystal X-ray diffraction.
Article
Chemistry, Multidisciplinary
Sang Loon Tan, Yee Seng Tan, Muhammad Syafiq Bin Shahari, Ahmad Junaid, Anton Dolzhenko, Edward R. T. Tiekink
Summary: Two polymorphs, alpha and beta, of an N-2,6-diaryl-1,3,5-triazine-2,4-diamine derivative have been isolated and show distinct molecular packing and stability of molecular conformation. The alpha-polymorph features expansive, stabilising pi stacking interactions achieved by relatively unstable conformations. The beta-polymorph is the thermodynamically stable form and can be obtained by the conversion of the alpha-polymorph over time or by heating.
Review
Chemistry, Medicinal
Muhammad Syafiq Bin Shahari, Anton V. Dolzhenko
Summary: N-2,6-substituted 1,3,5-triazine-2,4-diamines (N-2-substituted guanamines) are a diverse scaffold with potential in the development of bioactive molecules. They can be used to construct compounds targeting various enzymes, receptors, transporters, and nucleic acids, with therapeutic applications in cancer, inflammation, and CNS disorders.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Crystallography
Zhi-Yong Wang, Peng-Xin Qian, Xian-Jiong Yang, Qi-Long Zhang, Hong Xu, Ya-Li Huang
Summary: This compound is C8H8N6 center dot C5H9O2, monoclinic I2/alpha (no. 15) with lattice parameters a = 13.2666(17) angstrom, b = 11.0435(15) angstrom, c = 19.778(3) angstrom, beta = 92.707(10)degrees. The unit cell volume is V = 2894.4(7) angstrom(3), and it contains 8 molecules. The R-factor and weighted R-factor are R-gt(F) = 0.0528 and wR(ref)(F-2) = 0.1511, respectively.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Chemistry, Multidisciplinary
Zhi-Hao Zhang, Shaoqing Li, Yizhe Yan, Jianbo Qu, Jian-Yong Wang
Summary: The novel fast-responsive fluorescent probe TzAr-H2S can quickly detect H2S with good selectivity, large Stokes shift, and low cytotoxicity within 20 seconds, providing a powerful tool for understanding the regulation mechanism of hydrogen sulfide in cells.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Organic
Wei Guo, Zhen Xie, Liuhuan Cai, Gongping Liu, Ling Deng, Weijie Mei, Xiaoying Zou, Yumei Zhong, Xiaoya Zhuo, Lvyin Zheng, Xiaolin Fan
Summary: A new photocatalyst-free visible-light-enhanced strategy for the synthesis of pyrazolo[1,5-a][1,3,5]triazine-2,4-diamines via the formation of electron donor-acceptor (EDA) complexes has been reported. The reaction involves three C-N bond formations in a one-pot protocol without the need for external transition metals, oxidants, bases, or ligands. This efficient methodology provides potential synthetic applications in drug research and development.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Rajesh Sahu, Saurav Yadav, Krishna Chaitanya Gunturu, Anant R. Kapdi
Summary: Sensing important metals in different environments is vital, and the use of fluorescent sensors in metal sensing is a widely applied method. This study introduces a phenothiazine-based fluorescent sensor for Cu(II) ions, which shows high selectivity compared to other transition metal salts. The Lewis acidity of the Cu(II) salt and a 1:1 ratio were found to enhance the sensing response in MeOH solvent.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Analytical
Wenjing Chen, Dongbao Hu, Meng Yang, Yi Zhu, Yunying Wu, Xi Li, Juntong Zhang, Jiqiu Yang, Yan Huang, Jianxin Xie
Summary: A highly sensitive and rapid fluorescent nanoprobe based on Cu/Ag nanoclusters was developed for the detection of 6-TG. The method showed simple operation, high sensitivity, and good selectivity, making it a promising candidate for the detection of 6-TG in biological samples.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Marta Koscak, Ivona Krosl, Biserka Zinic, Ivo Piantanida
Summary: In this study, novel peptidoids were synthesized by replacing and extending amino acids in a peptide sequence, and these peptidoids demonstrated similar metal ion binding properties as the parent peptide. Some of the peptidoids showed high affinity to Cu2+ ions and exhibited fluorescent and chiral circular dichroism responses upon Cu2+ ion binding. Additionally, these peptidoids were capable of binding to DNA and RNA, and Cu2+ ions were found to enhance the stability of the peptidoid-DNA/RNA complexes. These findings provide important insights for further investigations on the interaction between peptides and metal ions.
Article
Chemistry, Physical
Gamze Bakir Guven, Murat Cinarli, Emine Babur Sas, Onder Idil, Nermin Kahveci Yagci
Summary: A new Zn(II) complex of 2,4,6-tri(2-pyridyl)-1,3,5-triazine was prepared and characterized. The complex showed significant antimicrobial effects and DNA binding interactions. Various tests and studies were conducted to analyze its properties and behaviors in detail.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
