Article
Chemistry, Applied
A. Prasanna de Silva
Summary: The article provides an overview of the author's journey from the initial discoveries of fluorescent PET sensors and logic gates to their application in solid-based devices. Functional molecules are immobilized on various materials to serve various purposes such as analysis, identification, and emulation of animal and computer behavior.
Review
Chemistry, Inorganic & Nuclear
David C. Magri
Summary: This article critically reviews the evolution of fluorescence sensing at the University of Malta in the context of molecular logic-based computation. It showcases the design principle of photoinduced electron transfer (PET) and discusses redox-driven switching alongside traditional acid-base and ion-binding phenomena. The cross-pollination with internal charge transfer (ICT) further provides intelligent molecules with interesting and enhanced properties.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Matthew E. S. West, Chao-Yi Yao, Gavin Melaugh, Kyoko Kawamoto, Seiichi Uchiyama, A. Prasanna de Silva
Summary: Temperature-driven fluorescent NOT logic and proton-driven YES and NOT logic gates are demonstrated using different compounds and materials, along with additional logic gates. A polymeric molecular thermometer based on a copolymer is also showcased in the study.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Chao-Yi Yao, A. Prasanna de Silva
Summary: The general tool of fluorescent PET sensors/switches, based on molecular design principle with engineering features, is explained using frontier orbital energy diagrams. Fluorophores such as anthracene, 1,3-diaryl-Delta(2)-pyrazolines and 4-amino-1,8-naphthalimides are used along with receptors like amines, carboxylates, crown ethers and amino acids. This tool was widely adopted by a multinational corporation to develop a medical analyzer for electrolytes and gases, achieving commercial success. Moreover, it served as a springboard for the integration of chemistry and computer science through the field of molecular logic, which explores how molecules process information within our body. Molecular examples of simple logic gates and human-level computation of visual edge detection are also discussed.
Article
Spectroscopy
Abobakr A. Mohamed, Mahmoud A. Omar, Sayed M. Derayea, Mohamed Ahmed Elsayed, Islam M. Mostafa
Summary: A new fluorimetric method for the selective and sensitive quantification of nadifloxacin has been established by blocking the photoinduced electron transfer effect through pH adjustment. This method allows for the detection of nadifloxacin in its pure state and cream pharmaceutical formulation without interference from common excipients.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Multidisciplinary Sciences
Stanislav Zalis, Jan Heyda, Filip Sebesta, Jay R. Winkler, Harry B. Gray, Antonin Vlcek
Summary: The study elucidates the mechanism of charge transport over long distances through hole hopping via tryptophan/tyrosine chains, with experimental and theoretical analyses revealing key factors influencing the process. Experimental kinetics investigations demonstrated the acceleration effect of closely spaced tryptophans on long-range electron transfer, while theoretical calculations identified crossings between sensitizer-localized and charge-separated states in excited-state trajectories.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Multidisciplinary
Mateusz Reczynski, Dawid Pinkowicz, Koji Nakabayashi, Christian Nather, Jan Stanek, Marcin Koziel, Justyna Kalinowska-Tluscik, Barbara Sieklucka, Shin-ichi Ohkoshi, Beata Nowicka
Summary: The molecule chain exhibits a unique multiresponsive behavior to stimuli such as temperature, pressure, light, and humidity, leading to significant changes in magnetic susceptibility and color. This stimuli-responsive material can switch between two valence states and show thermal hysteresis at room temperature, as well as sensitivity to pressure and irradiation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Yiran Zhao, Julie Descamps, Brieg Le Corre, Yoan Leger, Alexander Kuhn, Neso Sojic, Gabriel Loget
Summary: This study investigates the application of photoinduced electrochemiluminescence (PECL) in designing anti-Stokes systems that convert infrared (IR) into visible light without direct electrical contact. By studying different types of Si-based closed bipolar electrodes (BPEs), it was found that bright and long-lasting emission can be triggered by external bias and IR illumination. The study also demonstrates the control of onset bias and anti-Stokes shift by the employed electrochemiluminescent (ECL) system.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Physical
Mingyue Liao, Jiaqing Cui, Mingxue Yang, Zhuangzhuang Wei, Yiming Xie, Canzhong Lu
Summary: Metalloporphyrin is an important macromolecular heterocyclic compound with potential applications in energy, environment, catalysis, and especially biological processes and biomedical applications. In this study, a series of butterfly-shaped and distorted tetrahedral geometry tetracobalt complexes were synthesized and coordinated with zinc meso-tetraphenylporphyrin (ZnTPP). The electron transfer from photo-excited ZnTPP to cobalt atoms was found to rely on the zinc-nitrogen coordination bond, resulting in the quenching of fluorescence intensity. These characteristics have important potential in inhibiting photodynamic therapy (PDT) side effects and can be further developed and researched for photonics, imaging, acoustics, photocatalysis, and related biomedicine, energy, and environment applications.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Physics, Fluids & Plasmas
Ian Seet, Thomas E. Ouldridge, Jonathan P. K. Doye
Summary: Landauer's principle sets a lower limit on the work required for logically irreversible operations, which can be overcome by using logically reversible gates. This paper presents the design and simulation of molecular mechanical logic gates that approach the limits of thermodynamic reversibility, even in the presence of thermal noise. The study demonstrates the feasibility of constructing and simulating arbitrary combinatorial reversible circuits with these gates.
Article
Chemistry, Physical
Mohit Kumar, Jaeseong Lim, Hyunwoo Kang, Sangwan Kim, Hyungtak Seo
Summary: This study demonstrates the development of photon-triggered, self-biased graphene-based electronic circuits that can operate in a wide spectral range. The proposed devices, including various transistors and logic gates, exhibit fast temporal processing and have potential applications in high-speed neuromorphic sensing.
Article
Nanoscience & Nanotechnology
Haobo Sun, Jingliang Liu, Jinming Kong, Jian Zhang, Xueji Zhang
Summary: In this study, a logic gate recognition biosensing platform based on the trinity molecular recognition mode was developed for quantitative measurement of microRNAs (miRNAs), particularly in cancer diagnosis. The platform exhibited high sensitivity and a linear range from 0.1 nM to 10 aM, with a detection limit of 4.48 aM under optimal experimental conditions. A Zn(TCPP) photocatalytic electron transfer reversible tion signal amplification strategy was adopted to achieve excellent detection performance. This study is the first to report the preparation of signal amplification biosensors using PET-RAFT for tumor marker detection. With its outstanding detection performance, the sensor system can be applied to early screening of lung cancer patients.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Ran Liu, Yingmei Han, Feng Sun, Gyan Khatri, Jaesuk Kwon, Cameron Nickle, Lejia Wang, Chuan-Kui Wang, Damien Thompson, Zong-Liang Li, Christian A. Nijhuis, Enrique del Barco
Summary: This study presents a controllable ultra-minimalistic circuit element using single-molecule logic operations, which requires stable currents from multiple orthogonal inputs. By modulating the output current in real-time based on orthogonal input bias and gate voltages, reliable and low-voltage operations are achieved. Various logic gates are successfully implemented, demonstrating stable multilogic operations.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Wenxing Yang, Yawei Liu, Tomas Edvinsson, Ashleigh Castner, Shihuai Wang, Sheng He, Sascha Ott, Leif Hammarstrom, Tianquan Lian
Summary: The interaction between surface adsorbate vibration and intraband electron absorption in nanocrystals affects the photophysical properties of both nanocrystals and surface adsorbates, impacting the performance of hybrid photocatalysts composed of semiconductor nanocrystals and molecular catalysts. The observation of Fano resonances between the intraband transition of photogenerated electrons in CdS and CdSe nanocrystals and CO stretching vibrational modes of adsorbed molecular catalysts provides new insights into fundamental interactions in these hybrid assemblies for artificial photosynthesis.
Article
Chemistry, Multidisciplinary
Soosang Chae, Won Jin Choi, Ivan Fotev, Eva Bittrich, Petra Uhlmann, Mathias Schubert, Denys Makarov, Jens Wagner, Alexej Pashkin, Andreas Fery
Summary: This study demonstrates mechanical-strain-gated electric switches based on a thin-film architecture that successfully achieves an insulator-to-conductor transition and a nine-order magnitude change in conductivity within a tunable working strain range. By realizing strain-controlled basic and universal logic gates, mechanical-force-controlled electric logic circuits are achieved.
ADVANCED MATERIALS
(2021)
