A novel phenotype for the dynein heavy chain mutation Loa: Altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons

Cytoplasmic dynein in neurodegeneration

(2011) Judith Eschbach et al.   PHARMACOLOGY & THERAPEUTICS

Misfolded SOD1 Associated with Motor Neuron Mitochondria Alters Mitochondrial Shape and Distribution Prior to Clinical Onset

(2011) Christine Vande Velde et al.   PLoS One

Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites

(2010) Lukas C. Kapitein et al.   CURRENT BIOLOGY

A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons

(2010) Kerstin E. Braunstein et al.   HUMAN MOLECULAR GENETICS

TheLegs at odd angles(Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1G93AMouse Model for Motor Neuron Disease

(2010) Ali Morsi El-Kadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurodegenerative Mutation in Cytoplasmic Dynein Alters Its Organization and Dynein-Dynactin and Dynein-Kinesin Interactions

(2010) Wenhan Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cytoplasmic dynein tail mutation impairs motor processivity

(2010) Kassandra M. Ori-McKenney et al.   NATURE CELL BIOLOGY

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Mitochondrial Function, Morphology, and Axonal Transport in Amyotrophic Lateral Sclerosis

(2009) Jordi Magrané et al.   ANTIOXIDANTS & REDOX SIGNALING

A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

(2009) E. Perlson et al.   JOURNAL OF NEUROSCIENCE

Dynein motor contributes to stress granule dynamics in primary neurons

(2009) N.-P. Tsai et al.   NEUROSCIENCE

A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse

(2009) Z.C. Baquet et al.   NEUROSCIENCE

Neurotrophic Modulation of Motor Neuron Development

(2009) Thomas W. Gould et al.   NEUROSCIENTIST

Mice with a mutation in the dynein heavy chain 1 gene display sensory neuropathy but lack motor neuron disease

(2008) Luc Dupuis et al.   EXPERIMENTAL NEUROLOGY

A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes

(2008) Junghoon Ha et al.   JOURNAL OF CELL BIOLOGY

Retrograde axonal transport and motor neuron disease

(2008) Anna-Lena Strm et al.   JOURNAL OF NEUROCHEMISTRY

The Neurotrophic Effects of Glial Cell Line-Derived Neurotrophic Factor on Spinal Motoneurons Are Restricted to Fusimotor Subtypes

(2008) T. W. Gould et al.   JOURNAL OF NEUROSCIENCE

Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons

(2008) Yi Zheng et al.   NATURE CELL BIOLOGY

Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death

(2008) H. S. Ilieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic dynein could be key to understanding neurodegeneration

(2008) Gareth T Banks et al.   GENOME BIOLOGY