Article
Multidisciplinary Sciences
Rockelle S. Guthrie, Davide Ciliberti, Emily A. Mankin, Gina R. Poe
Summary: A study found that the neocortex and hippocampus in the human brain may exhibit asynchronous state transitions during sleep, which questions the assessment of the functions and drivers of sleep states throughout the brain from a whole-brain perspective.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Mariel Muller, Cyriel M. A. Pennartz, Conrado Bosman, Umberto Olcese
Summary: Understanding the neural mechanisms of sensory processing has been a key objective for neuroscientists in the past decades. While many studies have focused on the rodent whisker system as a model for tactile processing, it remains unclear to what extent these findings are applicable to the human somatosensory system. To address this, researchers developed a restrained vibrotactile detection task involving the limb system in mice. The mice were able to learn the task with satisfactory performance and short training times, making this a versatile method for studying tactile processing at the neuron level in a different system.
Article
Neurosciences
Arindam Bhattacharjee, Christoph Braun, Cornelius Schwarz
Summary: The study investigated whether humans implement a temporally local coding scheme for perceptual decisions in the tactile system. The results showed that manipulating local pulse shape significantly affects psychophysical performance, suggesting the existence of temporally local coding in human tactile perception. Different kinematic layouts of pulses resulted in distinct differences in performance, indicating that temporally local coding may not be tuned to a unique kinematic variable.
Article
Neurosciences
Carla Pais-Vieira, Mehrab K. Allahdad, Andre Perrotta, Andre S. Peres, Carolina Kunicki, Mafalda Aguiar, Manuel Oliveira, Miguel Pais-Vieira
Summary: This study used EEG signals to investigate the tactile width discrimination task in humans and found that fronto-parietal electrodes encoded between-subjects' performances while parieto-occipital electrodes encoded within-subjects' performances, supporting the notion that tactile width discrimination processing is associated with a complex asymmetrical network involving fronto-parieto-occipital electrodes.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Biology
Emma Mendelsohn, Noam Ross, Carlos Zambrana-Torrelio, T. P. Van Boeckel, Ramanan Laxminarayan, Peter Daszak
Summary: This study examines the factors related to antimicrobial resistance (AMR) emergence in humans using global data. It finds a positive correlation between AMR emergence and antibiotic consumption in humans. The study also suggests that human travel may contribute to the spread of novel AMR strains.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Article
Neurosciences
Laura E. Meine, Jana Meier, Benjamin Meyer, Michele Wessa
Summary: Animal research has shown that control is crucial in the brain's stress response. This study investigated the effects of controllable vs. uncontrollable aversive stimuli on brain function in humans, finding that being able to control the stressor led to reduced activation in stress-responsive regions and decreased feelings of helplessness. The findings support the role of the ventromedial prefrontal cortex in regulating stress responses dependent on controllability.
Article
Computer Science, Software Engineering
Thomas Howard, Karina Driller, William Frier, Claudio Pacchierotti, Maud Marchal, Jessica Hartcher-O'Brien
Summary: This study investigates the perception of ultrasound mid-air haptic (UMH) devices, focusing on two key aspects: generating continuous or discontinuous tactile shape sensations, and the achievable resolution of UMH interfaces. A user study reveals that a distance of at least 32.3 mm between two focal points is required to perceive a gap, but there is high variability among different participants. Acoustic simulations show a non-linear relationship between actual pressure spacing and nominal focal point spacing. This work provides important insights for the design and perception of UMH shapes.
ACM TRANSACTIONS ON APPLIED PERCEPTION
(2023)
Article
Psychology, Multidisciplinary
Fernando Gutierrez, Josep M. Peri, Eva Bailles, Barbara Sureda, Miguel Garriz, Gemma Vall, Myriam Cavero, Aida Mallorqui, Jose Ruiz Rodriguez
Summary: The fast-slow paradigm of life history focuses on the pace at which individuals grow, mate, and reproduce. This study found different life history axes and their association with sociosexual strategies and personality pathology traits.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Microbiology
Kanika Vanshylla, Veronica Di Cristanziano, Franziska Kleipass, Felix Dewald, Philipp Schommers, Lutz Gieselmann, Henning Gruell, Maike Schlotz, Meryem S. Ercanoglu, Ricarda Stumpf, Petra Mayer, Matthias Zehner, Eva Heger, Wibke Johannis, Carola Horn, Isabelle Suarez, Norma Jung, Susanne Salomon, Kirsten Alexandra Eberhardt, Birgit Gathof, Gerd Faetkenheuer, Nico Pfeifer, Ralf Eggeling, Max Augustin, Clara Lehmann, Florian Klein
Summary: The study reveals a wide spectrum of neutralizing antibody response to SARS-CoV-2, with sustained antibodies in the majority of individuals with mild COVID-19 for up to 10 months after infection.
CELL HOST & MICROBE
(2021)
Article
Biochemistry & Molecular Biology
Masaru Yamaguchi, Yota Tatara, Eka Djatnika Nugraha, Dwi Ramadhani, Yuki Tamakuma, Yoshiaki Sato, Tomisato Miura, Masahiro Hosoda, Shinji Yoshinaga, Mukh Syaifudin, Ikuo Kashiwakura, Shinji Tokonami
Summary: This study conducted proteomic analysis and oxidative modification profiling on blood samples collected from residents in high-level natural background radiation area and normal-level area in Mamuju, Indonesia and found dose-dependent oxidative modifications in human serum albumin. This finding provides a possibility for developing a methodology to evaluate biological responses to low-dose radiation exposure.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Engineering, Biomedical
Aayushi Khajuria, Deepak Joshi
Summary: The integration of vibrotactile sensory feedback (VF) with balancing exercises has been shown to improve postural stability in lower limb amputees. This study investigated the cortical processes involved in balance control and how they are influenced by VF. Data from six transfemoral amputees were collected, and the results showed that VF elicited strong theta and gamma oscillations, leading to improved limit of stability (LOS). The secondary somatosensory cortex-S2 processed the sensory information from VF by reducing theta power, while the fronto-central (FC) region executed the motor response to improve LOS by increasing gamma power. The functional connectivity between S2 and FC was stronger with VF, and the two regions were strongly connected during perception of VF. These findings provide insights into the cortical mechanisms of balance improvement in amputees.
MEDICAL ENGINEERING & PHYSICS
(2022)
Article
Psychology, Biological
Kelley Knapp-Kline, Christopher Ring, David Emmerich, Jasper Brener
Summary: The ability to detect heartbeat sensations plays a crucial role in evaluating individual differences in sensitivity to internal stimuli. The experiment confirmed the involvement of the somatosensory system in cardioception and highlighted the roles of both Pacinian and non-Pacinian somatosensory mechanoreceptors in heartbeat detection.
Article
Multidisciplinary Sciences
Simone Holler, German Kostinger, Kevan A. C. Martin, Gregor F. P. Schuhknecht, Ken J. Stratford
Summary: Researchers reconstructed mammalian brain circuits using high-throughput electron-microscopic techniques, revealing a linear relationship between synapse size and strength, which provides a key missing link in assigning physiological weights to neuronal wiring diagrams. Additionally, their study found that neocortical synapses operate with multivesicular release, suggesting they are more complex computational devices than previously thought.
Article
Psychology, Multidisciplinary
Valentina Cesari, Elena Marinari, Marco Laurino, Angelo Gemignani, Danilo Menicucci
Summary: The study found that sleep deprivation increased both mental and physical workload, without changes in cognitive and physiological indices. Specific physiological correlates of the attentional systems were identified, with changes in head movement amplitude and facial temperature correlating with changes in alertness levels during attention tasks.
BEHAVIORAL SCIENCES
(2021)
Article
Medicine, General & Internal
John D. Scott, Muhammad S. Sajid, Emily L. Pascoe, Janet E. Foley
Summary: A one-day clinic in Ontario, Canada, identified B. odocoilei in two out of 19 participants through PCR testing and DNA sequencing. The DNA amplicons from these individuals closely matched the type strains of B. odocoilei in GenBank. Both patients exhibited hallmark symptoms of human babesiosis. This discovery provides evidence of B. odocoilei's pathogenicity to humans and the potential for serological cross-reactivity.
Review
Neurosciences
Dominique L. Pritchett, Joshua H. Siegle, Christopher A. Deister, Christopher I. Moore
CURRENT OPINION IN NEUROBIOLOGY
(2015)
Article
Neurosciences
Matthew D. Sacchet, Roan A. LaPlante, Qian Wan, Dominique L. Pritchett, Adrian K. C. Lee, Matti Haemaelaeinen, Christopher I. Moore, Catherine E. Kerr, Stephanie R. Jones
JOURNAL OF NEUROSCIENCE
(2015)
Editorial Material
Neurosciences
David Badre, Michael J. Frank, Christopher I. Moore
Article
Multidisciplinary Sciences
Maxwell A. Sherman, Shane Lee, Robert Law, Saskia Haegens, Catherine A. Thorn, Matti S. Hamalainen, Christopher I. Moore, Stephanie R. Jones
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2016)
Review
Neurosciences
Catherine E. Kerr, Matthew D. Sacchet, Saraw W. Lazar, Christopher I. Moore, Stephanie R. Jones
FRONTIERS IN HUMAN NEUROSCIENCE
(2013)
Article
Neurosciences
Joshua H. Siegle, Dominique L. Pritchett, Christopher I. Moore
NATURE NEUROSCIENCE
(2014)
Article
Neurosciences
Elizabeth A. Normand, Shane R. Crandall, Catherine A. Thorn, Emily M. Murphy, Bettina Voelcker, Catherine Browning, Jason T. Machan, Christopher I. Moore, Barry W. Connors, Mark Zervas
Article
Biology
Samuel A. Neymotin, Dylan S. Daniels, Blake Caldwell, Robert A. McDougal, Nicholas T. Carnevale, Mainak Jas, Christopher Moore, Michael L. Hines, Matti Hamalainen, Stephanie R. Jones
Article
Biology
Jakob Voigts, Christopher A. Deister, Christopher Moore
Article
Biochemistry & Molecular Biology
Arif A. Hamid, Michael J. Frank, Christopher Moore
Summary: Evidence suggests that dopamine plays a role in shaping learning by encoding reward prediction errors, with tailored dynamics for striatal targets based on regional specialization. Dopamine activity shows wave-like spatiotemporal patterns in the dorsal striatum, propagating between subregions based on task demands.
Article
Neurosciences
Robert G. Law, Sarah Pugliese, Hyeyoung Shin, Danielle D. Sliva, Shane Lee, Samuel Neymotin, Christopher Moore, Stephanie R. Jones
Summary: Transient neocortical events in the 15-29 Hz beta band are reliable predictors of sensory perception, with prestimulus beta event rates correlating with sensory suppression. Cellular and circuit mechanisms underlying these correlations were investigated, showing that bursts from higher-order thalamus and slow supragranular inhibition play a key role in sensory information suppression. The study also suggests that beta events occurring simultaneously with tactile stimulation may lead to facilitated perception before inhibition is recruited.
Article
Clinical Neurology
Judith D. Schaechter, Casper A. M. M. van Oers, Benjamin N. Groisser, Sara S. Salles, Mark G. Vangel, Christopher I. Moore, Rick M. Dijkhuizen
NEUROREHABILITATION AND NEURAL REPAIR
(2012)
Proceedings Paper
Engineering, Biomedical
Joshua H. Siegle, Marie Carlen, Konstantinos Meletis, Li-Huei Tsai, Christopher I. Moore, Jason Ritt
2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
(2011)
Article
Neurosciences
Jakob Voigts, Joshua H. Siegle, Dominique L. Pritchett, Christopher L. Moore
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2013)