Article
Psychology, Multidisciplinary
Ragnhild Stokke Lundetrae, Ingvild West Saxvig, Harald Aurlien, Sverre Lehmann, Bjorn Bjorvatn
Summary: The study showed that CPAP treatment significantly reduced insomnia symptoms in patients with OSA, with a greater reduction in adherent patients. The proportion of patients with chronic insomnia also significantly decreased after CPAP treatment.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Yoko Fujino, Yasunori Oka, Tomoko Wakamura
Summary: This study found that seasonal differences can impact the CPAP adherence of patients with obstructive sleep apnea. Patients in the adherent group had lower CPAP use rate and shorter duration in summer, while the non-adherent group showed significant differences between winter and summer.
Article
Health Care Sciences & Services
Angela Fidler Pfammatter, Bonnie Olivia Hughes, Becky Tucker, Harry Whitmore, Bonnie Spring, Esra Tasali
Summary: This study developed a mobile health tool that integrated weight loss features with novel CPAP adherence tracking for patients with OSA. The tool tracked CPAP wear time relative to time spent in bed and included push notifications to foster adherence. Future research is needed to evaluate the effectiveness of this tool in improving OSA treatment adherence.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Critical Care Medicine
Chloe Gerves-Pinquie, Sebastien Bailly, Francois Goupil, Thierry Pigeanne, Sandrine Launois, Laurene Leclair-Visonneau, Philippe Masson, Acya Bizieux-Thaminy, Margaux Blanchard, AbdelKebir Sabil, Dany Jaffuel, Jean-Louis Racineux, Wojciech Trzepizur, Frederic Gagnadoux
Summary: In real-life clinical data, there is a dose-response relationship between positive airway pressure (PAP) therapy and cardiovascular risk in patients with obstructive sleep apnea (OSA). Increasing PAP adherence may help improve cardiovascular outcomes in OSA patients.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Geriatrics & Gerontology
Kathy C. Richards, Alicia J. Lozano, Jennifer Morris, Stephen T. Moelter, Wenyan Ji, Vani Vallabhaneni, Yanyan Wang, Luqi Chi, Eric M. Davis, Cindy Cheng, Vanessa Aguilar, Sneha Khan, Mira Sankhavaram, Alexandra L. Hanlon, David A. Wolk, Nalaka Gooneratne
Summary: This study explores the predictors of CPAP adherence in older adults with amnestic mild cognitive impairment, as well as the need for culturally tailored interventions to improve adherence in Black patients.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Respiratory System
Nantaporn Tiyapun, Kanokkarn Sunkonkit, Warawut Chaiwong, Ratirat Worasuthaneewan, Theerakorn Theerakittikul
Summary: This study explored the factors influencing CPAP adherence in elderly OSA patients. It was found that elderly patients with adverse attitudes towards CPAP use and female patients had lower adherence rates. Therefore, individualized indications and treatment of CPAP should be considered in the elderly, with regular monitoring to address compliance and tolerance issues.
JOURNAL OF THORACIC DISEASE
(2023)
Article
Medicine, General & Internal
Hyunjin Jo, Sujung Choi, Dongyeop Kim, Eunyeon Joo
Summary: Patients with epilepsy have milder characteristics of obstructive sleep apnea (OSA), but because of the high coexistence of OSA and epilepsy, continuous positive airway pressure (CPAP) therapy can reduce the frequency of seizures. Therefore, it is important to evaluate the presence of OSA in patients with epilepsy and provide concurrent treatment.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Jonathan Villa Alvarez, Robert Dales, Tetyana Kendzerska
Summary: In this retrospective observational study, readily available demographics and factors related to obstructive sleep apnea (OSA) were found to be associated with positive airway pressure (PAP) adherence. The study also confirmed previous findings on age and sex disparities in adherence to PAP.
Article
Public, Environmental & Occupational Health
Lizabeth A. Goldstein, Natalie Purcell, Kathleen F. Sarmiento, Thomas C. Neylan, Shira Maguen
Summary: The study investigated barriers to optimal use of PAP therapy for sleep apnea, finding that physical and psychological barriers were the most commonly reported by patients. However, these barriers were not associated with therapy hours. Providers mainly recommended solutions for physical barriers and rarely addressed psychological barriers.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2022)
Article
Medicine, General & Internal
Jae Hyuk Choi, Eunkyu Lee, Sang Duk Hong, Seung Kyu Chung, Yong Gi Jung, Hyo Yeol Kim
Summary: A retrospective analysis of OSA patients undergoing CPAP therapy showed significant improvements in laryngopharyngeal reflux symptoms and examination findings, independent of body mass index or OSA severity.CPAP treatment has the potential to reduce laryngeal reflux symptoms and improve laryngeal examination results in OSA patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nursing
Chestharid Borriboon, Jindarat Chaiard, Chiraporn Tachaudomdach, Sue Turale
Summary: This study aimed to investigate the relationship between health belief model factors and CPAP adherence in Thai individuals with obstructive sleep apnoea. Results showed a low rate of CPAP adherence, with perceived seriousness of the conditions being the only significant factor associated with adherence. Healthcare professionals, especially nurses, should provide support and education to encourage regular CPAP use and be aware of psychological factors affecting patients' perception of sleep apnoea and CPAP treatment. Intervention strategies targeting these factors should be developed and implemented in clinical practice.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Respiratory System
Min Qiao, Yiyu Xie, Armand Wolff, Jeff Kwon
Summary: Studies have shown that long-term compliance with CPAP treatment is low in patients with mild sleep apnea. Compliance during the first three months of treatment can predict long-term adherence to CPAP.
BMC PULMONARY MEDICINE
(2023)
Article
Clinical Neurology
Elif Torun Parmaksiz
Summary: A short-term daytime CPAP trial before the titration night may lead to longer and more efficient sleep on the titration night, as well as better CPAP adherence at one month follow-up for OSA patients.
SLEEP AND BREATHING
(2021)
Article
Clinical Neurology
Faith S. Luyster, Quan Ni, Kent Lee, Christine Harrison, Vaibhav H. Ramprasad, Ryan J. Soose, Patrick J. Strollo
Summary: This study explored the factors associated with the usage of upper airway stimulation (UAS) in obstructive sleep apnea patients. The study found that low users were more likely to have insomnia and anxiety symptoms, while high users reported more positive experiences with the treatment. This suggests that insomnia and anxiety can influence patients' experiences and adherence to UAS therapy.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2022)
Article
Clinical Neurology
Melissa S. Xanthopoulos, Maria N. Nelson, Whitney Eriksen, Frances K. Barg, Kelly C. Byars, Stacey L. Ishman, Anna J. Esbensen, Jareen Meinzen-Derr, Christine H. Heubi, Neepa S. Gurbani, Ruth Bradford, Suzanna Hicks, Ignacio E. Tapia
Summary: This study conducted qualitative semi-structured phone interviews with 40 caregivers of children with Down syndrome and obstructive sleep apnea syndrome (OSAS) treated with positive airway pressure (PAP). The study found that factors affecting PAP adherence included accessing supplies, interactions with the medical team and equipment company, and the children's unique needs and behaviors. Suggestions for improving PAP adherence included improving communication, emphasizing patience, using visual supports, and providing social support and education for extended family members.
Editorial Material
Clinical Neurology
Douglas M. Wallace, Alexander Sweetman
SLEEP AND BREATHING
(2021)
Article
Clinical Neurology
Christian Agudelo, Wassim Tarraf, Benson Wu, Douglas M. Wallace, Sanjay R. Patel, Susan Redline, Sonya Kaur, Martha Daviglus, Phyllis C. Zee, Guido Simonelli, Yasmin Mossavar-Rahmani, Daniela Sotres-Alvarez, Donglin Zeng, Linda C. Gallo, Hector M. Gonzalez, Alberto R. Ramos
Summary: In a cohort of mostly middle-aged Hispanic/Latinos, longer sleep-onset latency was associated with declines in global cognitive function, verbal learning, and verbal memory and cross-sectionally associated with verbal learning, verbal memory, and word fluency. Sleep fragmentation was not associated with cognitive change.
ALZHEIMERS & DEMENTIA
(2021)
Article
Critical Care Medicine
Jason C. Ong, Megan R. Crawford, Douglas M. Wallace
Summary: This review highlights the clinical challenges and recent advancements in the management of patients with comorbid insomnia and sleep apnea, emphasizing innovative approaches in evaluation and treatment of COMISA and discussing patient-centered care opportunities in integrating characteristics, preferences, and accessibility to optimize patient care.
Article
Clinical Neurology
Kevin A. Gonzalez, Wassim Tarraf, Douglas M. Wallace, Ariana M. Stickel, Neil Schneiderman, Susan Redline, Sanjay R. Patel, Linda C. Gallo, Yasmin Mossavar-Rahmani, Martha L. Daviglus, Phyllis C. Zee, Gregory A. Talavera, Daniela Sotres-Alvarez, Hector M. Gonzalez, Alberto Ramos
Summary: The study aimed to derive sleep phenotypes among diverse Hispanic/Latinos by using obstructive sleep apnea symptoms. It identified three main sleep phenotypes - Minimally Symptomatic, Excessive sleepiness, and Disturbed Sleep. Further research is needed to link derived sleep phenotypes to health comorbidities in diverse populations.
Article
Multidisciplinary Sciences
Douglas M. Wallace, Maria L. Alcaide, William K. Wohlgemuth, Deborah L. Jones Weiss, Claudia Uribe Starita, Sanjay R. Patel, Valentina Stosor, Andrew Levine, Carling Skvarca, Dustin M. Long, Anna Rubtsova, Adaora A. Adimora, Stephen J. Gange, Amanda B. Spence, Kathryn Anastos, Bradley E. Aouizerat, Yaacov Anziska, Naresh M. Punjabi
Summary: The prevalence of RLS was similar in men with and without HIV in the study. Screening for RLS may be considered among people with HIV with insomnia and with long-standing disease.
Review
Clinical Neurology
Alexander Sweetman, Leon Lack, R. Doug McEvoy, Simon Smith, Danny J. Eckert, Amal Osman, Jayne C. Carberry, Douglas Wallace, Phuc D. Nguyen, Peter Catcheside
Summary: Insomnia and obstructive sleep apnea frequently co-occur, with co-morbid insomnia and sleep apnea (COMISA) leading to greater morbidity for patients, complex diagnostic decisions for clinicians, and reduced response to treatment. Understanding the bidirectional relationships between insomnia and OSA is crucial for guiding personalized diagnostic and treatment approaches.
SLEEP MEDICINE REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Christian Agudelo, Alberto R. Ramos, Xiaoyan Sun, Sonya Kaur, Dylan F. Del Papa, Josefina M. Kather, Douglas M. Wallace
Summary: This study aims to identify modifiable risk factors of cognitive disease and finds that comorbid insomnia with sleep-disordered breathing (SDB) may be a modifiable risk factor for mild cognitive impairment (MCI). The results show that high risk of SDB with comorbid insomnia is associated with higher odds of MCI.
APPLIED SCIENCES-BASEL
(2022)
Article
Clinical Neurology
Bastien Lechat, Kelly A. Loffler, Douglas M. Wallace, Amy Reynolds, Sarah L. Appleton, Hannah Scott, Andrew Vakulin, Nicole Lovato, Robert Adams, Danny J. Eckert, Peter G. Catcheside, Alexander Sweetman
Summary: Co-morbid insomnia symptoms and sleep apnea are associated with worse sleep, daytime function, mental health, and quality of life. This study found that the symptoms of co-morbid insomnia and sleep apnea are associated with an increased risk of all-cause mortality.
NATURE AND SCIENCE OF SLEEP
(2022)
Article
Clinical Neurology
Alexander Sweetman, Leon Lack, Megan Crawford, Douglas M. Wallace
SLEEP MEDICINE CLINICS
(2022)
Review
Clinical Neurology
Alexander Sweetman, Seamas Farrell, Douglas M. Wallace, Megan Crawford
Summary: Comorbid insomnia and sleep apnoea (COMISA) is a common and debilitating sleep disorder. Cognitive behavioural therapy for insomnia (CBTi) has shown to be effective in treating COMISA patients, according to a systematic review and meta-analysis of previous studies.
JOURNAL OF SLEEP RESEARCH
(2023)
Review
Respiratory System
Alexander Sweetman, Amal Osman, Leon Lack, Megan Crawford, Douglas Wallace
Summary: Insomnia and sleep apnea often occur together, and people with co-morbid insomnia and sleep apnea experience worse sleep quality, mental health, physical health, quality of life, and longevity. Cognitive behavioral therapy is an effective treatment for patients with both treated and untreated sleep apnea, and it may also improve the management of sleep apnea. Further research is needed to understand the causes of co-morbid insomnia and sleep apnea and develop personalized treatment approaches.
CURRENT OPINION IN PULMONARY MEDICINE
(2023)
Review
Clinical Neurology
Earl Charles Crew, William K. Wohlgemuth, Amy M. Sawyer, Natasha J. Williams, Douglas M. Wallace
SLEEP MEDICINE CLINICS
(2021)
Article
Clinical Neurology
Amy M. Sawyer, Douglas M. Wallace, Luis F. Buenaver, Alexa J. Watach, Amy Blase, Bruno Saconi, Sanjay R. Patel, Samuel T. Kuna, Naresh M. Punjabi
SLEEP MEDICINE CLINICS
(2021)
Article
Clinical Neurology
Zhe He, Douglas M. Wallace, Andrea Barnes, Xiang Tang, Girardin Jean-Louis, Natasha J. Williams
Article
Multidisciplinary Sciences
Douglas M. Wallace, Maria L. Alcaide, William K. Wohlgemuth, Deborah L. Jones Weiss, Claudia Uribe Starita, Sanjay R. Patel, Valentina Stosor, Andrew Levine, Carling Skvarca, Dustin M. Long, Anna Rubtsova, Adaora A. Adimora, Stephen J. Gange, Amanda B. Spence, Kathryn Anastos, Bradley E. Aouizerat, Yaacov Anziska, Naresh M. Punjabi
Summary: The prevalence of restless legs syndrome (RLS) in men with and without HIV was similar, with HIV status not associated with RLS prevalence. White race, anemia, depression, and antidepressant use were independently associated with RLS. Men with HIV and RLS reported poorer sleep quality, greater sleepiness, and worse objective sleep efficiency/fragmentation compared to men without HIV/RLS.