Cancer ‘survivor-care’: I. the α7 nAChR as potential target for chemotherapy-related cognitive impairment

Effects on the visual system might contribute to some of the cognitive deficits of cancer chemotherapy-induced ‘chemo-fog’

(2010) R. B. Raffa et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models

(2010) Christopher J. O’Donnell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nicotinic actions on neuronal networks for cognition: General principles and long-term consequences

(2009) Rogier B. Poorthuis et al.   BIOCHEMICAL PHARMACOLOGY

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

(2009) Christopher J. O’Donnell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

(2009) Morten Thomsen et al.   CURRENT PHARMACEUTICAL DESIGN

Is a picture worth a thousand (forgotten) words?: neuroimaging evidence for the cognitive deficits in ‘chemo-fog’/’chemo-brain’

(2009) R. B. Raffa   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Deletion of the  7 Nicotinic Acetylcholine Receptor Gene Improves Cognitive Deficits and Synaptic Pathology in a Mouse Model of Alzheimer's Disease

(2009) G. Dziewczapolski et al.   JOURNAL OF NEUROSCIENCE

Pro-Cognitive and Antipsychotic Efficacy of the α7 Nicotinic Partial Agonist SSR180711 in Pharmacological and Neurodevelopmental Latent Inhibition Models of Schizophrenia

(2009) Segev Barak et al.   NEUROPSYCHOPHARMACOLOGY

Spatial and intracellular relationships between the α7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse

(2009) A.M. Duffy et al.   NEUROSCIENCE

A cog in cognition: How the α7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits

(2009) Steven C. Leiser et al.   PHARMACOLOGY & THERAPEUTICS

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Initial Phase 2 Trial of a Nicotinic Agonist in Schizophrenia

(2008) Robert Freedman et al.   AMERICAN JOURNAL OF PSYCHIATRY

Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity

(2008) Brad A. Acker et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Preclinical Characterization of A-582941: A Novel α7 Neuronal Nicotinic Receptor Agonist with Broad Spectrum Cognition-Enhancing Properties

(2008) Karin R. Tietje et al.   CNS Neuroscience & Therapeutics

Smoking, dementia and cognitive decline in the elderly, a systematic review

(2008) Ruth Peters et al.   BMC Geriatrics

Aromatic residues at position 55 of rat α7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization

(2007) Elaine A. Gay et al.   JOURNAL OF PHYSIOLOGY-LONDON