Clinical Pharmacokinetics and Drug-Drug Interactions of Endothelin Receptor Antagonists in Pulmonary Arterial Hypertension

Addition of Sildenafil to Long-Term Intravenous Epoprostenol Therapy in Patients with Pulmonary Arterial Hypertension

(2013) Gérald Simonneau   ANNALS OF INTERNAL MEDICINE

Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension

(2011) Robyn J. Barst et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Mutual pharmacokinetic interactions between bosentan and lopinavir/ritonavir in healthy participants

(2010) Jasper Dingemanse et al.   ANTIVIRAL THERAPY

Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytesThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.

(2010) J. Craig Hartman et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Effect of Steady-State Ambrisentan on the Pharmacokinetics of a Single Dose of the Oral Contraceptive Norethindrone (Norethisterone) 1 mg/Ethinylestradiol 35 μg in Healthy Subjects

(2010) Rebecca Spence et al.   CLINICAL DRUG INVESTIGATION

Effects of Rifampicin (Rifampin) on the Pharmacokinetics and Safety of Ambrisentan in Healthy Subjects

(2010) Brooke Harrison et al.   CLINICAL DRUG INVESTIGATION

Potential for Pharmacokinetic Interactions Between Ambrisentan and Cyclosporine

(2010) R Spence et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effects of Multiple Doses of Ambrisentan on the Pharmacokinetics of a Single Dose of Digoxin in Healthy Volunteers

(2010) Duncan B. Richards et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers

(2009) Gennyne Walker et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Metabolic Syndrome and Pulmonary Vascular Disease

(2009) Elizabeth A. Jackson et al.   CHEST

Effect of Ketoconazole on the Pharmacokinetic Profile of Ambrisentan

(2009) Duncan B. Richards et al.   JOURNAL OF CLINICAL PHARMACOLOGY

No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers

(2009) Rebecca Spence et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Long-Term Ambrisentan Therapy for the Treatment of Pulmonary Arterial Hypertension

(2009) Ronald J. Oudiz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Development and Pathology of Pulmonary Hypertension

(2009) Rubin M. Tuder et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension

(2009) Robyn J. Barst et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diagnosis and Assessment of Pulmonary Arterial Hypertension

(2009) David B. Badesch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ambrisentan Therapy in Patients With Pulmonary Arterial Hypertension Who Discontinued Bosentan or Sitaxsentan Due to Liver Function Test Abnormalities

(2008) Michael D. McGoon et al.   CHEST

Ambrisentan for the Treatment of Pulmonary Arterial Hypertension

(2008) Nazzareno Galiè et al.   CIRCULATION

Pharmacokinetics and Safety of Ambrisentan in Combination With Sildenafil in Healthy Volunteers

(2008) Rebecca Spence et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetic Interaction Between Tadalafil and Bosentan in Healthy Male Subjects

(2008) Rebecca E. Wrishko et al.   JOURNAL OF CLINICAL PHARMACOLOGY