The Need for Modeling and Simulation to Design Clinical Investigations in Children

Fluconazole Dosing for the Prevention or Treatment of Invasive Candidiasis in Young Infants

(2010) Kelly C. Wade et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Dried Blood Spots as a Sample Collection Technique for the Determination of Pharmacokinetics in Clinical Studies: Considerations for the Validation of a Quantitative Bioanalytical Method

(2009) Neil Spooner et al.   ANALYTICAL CHEMISTRY

Proposals for model-based paediatric medicinal development within the current European Union regulatory framework

(2009) Efthymios Manolis et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Drug therapy in pediatrics: a developing field

(2009) Lisa Mathis et al.   Dermatologic Therapy

Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans

(2009) Brian J. Anderson et al.   Drug Metabolism and Pharmacokinetics

Leveraging prior quantitative knowledge in guiding pediatric drug development: a case study

(2009) Pravin R. Jadhav et al.   PHARMACEUTICAL STATISTICS

Efficacy, safety and tolerability of tipranavir coadministered with ritonavir in HIV-1-infected children and adolescents

(2008) Juan C Salazar et al.   AIDS

Candesartan Cilexetil Effectively Reduces Blood Pressure in Hypertensive Children

(2008) Amy M Franks et al.   ANNALS OF PHARMACOTHERAPY

The FDA Critical Path Initiative and Its Influence on New Drug Development

(2008) Janet Woodcock et al.   Annual Review of Medicine

Quantitative Disease, Drug, and Trial Models

(2008) Jogarao V.S. Gobburu et al.   Annual Review of Pharmacology and Toxicology

Population Pharmacokinetics of Fluconazole in Young Infants

(2008) K. C. Wade et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pediatric Antihypertensive Trial Failures

(2008) Daniel K. Benjamin et al.   HYPERTENSION

Efficacy, Safety, and Pharmacokinetics of Candesartan Cilexetil in Hypertensive Children Aged 6 to 17 Years

(2008) Howard Trachtman et al.   Journal of Clinical Hypertension

Leveraging Prior Quantitative Knowledge to Guide Drug Development Decisions and Regulatory Science Recommendations: Impact of FDA Pharmacometrics During 2004-2006

(2008) Yaning Wang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Improving Pediatric Dosing Through Pediatric Initiatives: What We Have Learned

(2008) W. Rodriguez et al.   PEDIATRICS

Pharmacokinetics and pharmacodynamics of fenoldopam mesylate for blood pressure control in pediatric patients

(2008) Gregory B Hammer et al.   BMC Anesthesiology

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure

(2007) Stefanie Albers et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY