Article
Biochemistry & Molecular Biology
Giulia Brunello, Kathrin Becker, Luisa Scotti, Dieter Drescher, Juergen Becker, Gordon John
Summary: The study aimed to examine the impact of three CHX-based mouthwashes on osteoblast-like cells in vitro. Results indicate that 0.2% CHX presented the highest cytotoxic effect, suggesting that its intraoperative use should be carefully considered.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Medicine, General & Internal
Fernando Luengo, Myroslav Solonko, Javier Sanz-Esporrin, Ignacio Sanz-Sanchez, David Herrera, Mariano Sanz
Summary: The surgical treatment of peri-implantitis showed significant clinical improvements, but had limited impact on microbiological and biochemical parameters.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Infectious Diseases
Michele Antonio Lopez, Pier Carmine Passarelli, Emmanuele Godino, Nicolo Lombardo, Francesca Romana Altamura, Alessandro Speranza, Andrea Lopez, Piero Papi, Giorgio Pompa, Antonio D'Addona
Summary: The study demonstrated the efficacy of HYBENX(R) in treating peri-implantitis and suggested that using HYBENX(R) along with open-flap debridement may be an effective technique, although further studies are needed to understand its potential benefits fully.
Review
Dentistry, Oral Surgery & Medicine
Ausra Ramanauskaite, Frank Schwarz, Emilio Alfredo Cafferata, Philipp Sahrmann
Summary: The aim of this study was to evaluate the efficacy of adjunctive/alternative photo/mechanical and physical implant-surface decontamination approaches compared to standard instrumentation in conjunction with surgical peri-implantitis treatment. The results showed that the use of air polishing or titanium brushes may be beneficial in reducing signs of inflammation.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Eun-Hyuk Lee, Sang-Woo Lee, Yongbeom Seo, Yu-Heng Deng, Young-Jun Lim, Ho-Beom Kwon, Kyungpyo Park, Hyunjoon Kong, Myung-Joo Kim
Summary: This article introduces a new method for treating peri-implantitis, which involves using oxygen bubbles to remove biofilm from implants and promote osseointegration without causing harm to surrounding tissues or implant surfaces.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yuki Ichioka, Jan Derks, Lena Larsson, Tord Berglundh
Summary: The aim of this study was to evaluate the effect of air-polishing (AP) and a combination of AP and alkaline electrolysed water (AEW) in surface decontamination of peri-implantitis-affected implants. The results showed that both treatment protocols were effective in biofilm removal, with only small proportions of residual bacteria or mineralized deposits observed. Furthermore, factors such as implant thread, implant zone, implant surface characteristics, and gender influenced the results.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
E. L. Bonn, A. Rohrhofer, F. X. Audebert, H. Lang, D. L. Auer, K. J. Scholz, P. Schuster, J. J. Wenzel, K. -A. Hiller, W. Buchalla, J. M. Gottsauner, V. Vielsmeier, B. Schmidt, F. Cieplik
Summary: Soon after the outbreak of COVID-19, preprocedural mouthwashes containing CPC and CHX were recommended for reducing viral load and infectivity in individuals potentially infected with SARS-CoV-2. This clinical trial found that the mouthwash significantly reduced viral load and infectivity in SARS-CoV-2-positive patients.
JOURNAL OF DENTAL RESEARCH
(2023)
Article
Infectious Diseases
David L. Auer, Xiaojun Mao, Annette Carola Anderson, Denise Muehler, Annette Wittmer, Christiane von Ohle, Diana Wolff, Cornelia Frese, Karl-Anton Hiller, Tim Maisch, Wolfgang Buchalla, Elmar Hellwig, Ali Al-Ahmad, Fabian Cieplik
Summary: This study reveals that clinical isolates of early colonizers of dental plaque can phenotypically adapt to antiseptics such as chlorhexidine digluconate (CHX) upon repeated exposure. Some strains showed increased biofilm formation capacity and exhibited antibiotic resistance to tetracycline and erythromycin.
Article
Materials Science, Multidisciplinary
Ruitao Zhang, Ting Yang, Suru Liu, Hao Wu, Jie Long, Li Xie
Summary: Due to the inefficiency of current treatment methods for peri-implantitis, a new electrochemical oxidation method was proposed to achieve complete plaque removal. The method involved anodizing the samples in fluoride electrolyte to form titanium dioxide nanotubes (TNT) at the biofilm-substrate interface, followed by abrasive blasting using glycine powder to remove both the nanotubes and biofilms. The TNT + AA method showed better cleaning potential and biocompatibility compared to the air-abrasion treatment, making it a promising approach for peri-implantitis treatment.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Claudio Pasquale, Nicola De Angelis, Elena Dellacasa, Roberto Raiteri, Fabrizio Barberis, Alberto Lagazzo, Stefano Benedicenti, Andrea Amaroli
Summary: This study investigates the effects of laser irradiation on titanium against peri-implant infection and suggests choosing a laser that causes less damage to titanium implants. In the past decade, there has been a significant increase in dental implants, leading to a rise in peri-implantitis cases. Laser therapy has become one of the preferred treatments for peri-implantitis. However, the type of laser used can impact the success of the therapy. The aim of this comparative experimental work was to compare the effects of the most commonly used lasers on grade 4 titanium surfaces, considering any structural damage they may cause. The results show that the 1064-nm Q-switch Nd:YAG nanosecond pulsed laser is more suitable for preserving implant morphology without inducing metal damage.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Stefano Storelli, Giulia Palandrani, Barbara Manfredi, Eugenio Romeo, Dario De Martis, Claudia Todaro, Ruggero Baena, Saturnino Marco Lupi
Summary: The aim of this study was to analyze and compare the effectiveness of two antibacterial gels in treating mucositis. Twenty-one patients were included in the study and divided into two groups. The results showed that both groups had improvements in periodontal indices, with the only complication being pigmentations in the control group. In conclusion, the antibacterial power and effectiveness of the two gels were similar, but further studies are needed to validate the results due to the small sample size.
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Motohiro Munakata, Akihiro Suzuki, Kikue Yamaguchi, Yu Kataoka, Minoru Sanda
Summary: This study aimed to investigate the effects of different mechanical debridement techniques on the removal of hard calcified materials on implant surfaces and the influence of defect morphology. The results showed that titanium and ultrasonic scaler were more effective for shallow defects, while ultrasonic scaler was more effective for deeper defects.
JOURNAL OF DENTAL SCIENCES
(2022)
Review
Dentistry, Oral Surgery & Medicine
Yvonne C. M. de Waal, Lewis Winning, Andreas Stavropoulos, Ioannis Polyzois
Summary: Adjunctive chemical approaches for implant surface decontamination may offer an advantage over sub-marginal instrumentation alone, in terms of improved probing depth. However, the effects on other outcome variables were inconsistent or showed no differences.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Infectious Diseases
Kathrin Becker, Giulia Brunello, Luisa Scotti, Dieter Drescher, Gordon John
Summary: The study demonstrates that mouthwashes containing a reduced concentration of CHX combined with CPC show high antibacterial properties and can effectively reduce the viability of bacteria in oral biofilms. These mouthwashes have the potential to be used as long-term antibacterial agents with reduced side effects.
Article
Dentistry, Oral Surgery & Medicine
Nicola Pranno, Maria Paola Cristalli, Fabio Mengoni, Ilaria Sauzullo, Susanna Annibali, Antonella Polimeni, Gerardo La Monaca
Summary: In an ex vivo model, mechanical debridement was found to be significantly more effective than chemical decontamination in removing bacterial biofilms from infected implant surfaces.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yvonne C. M. de Waal, Gerry M. Raghoebar, Henny J. A. Meijer, Edwin G. Winkel, Arie Jan van Winkelhoff
CLINICAL ORAL IMPLANTS RESEARCH
(2016)
Article
Dentistry, Oral Surgery & Medicine
Y. C. de Waal, H. V. Eijsbouts, E. G. Winkel, A. J. van Winkelhoff
JOURNAL OF PERIODONTOLOGY
(2017)
Article
Dentistry, Oral Surgery & Medicine
Y. C. M. de Waal, G. M. Raghoebar, H. J. A. Meijer, E. G. Winkel, A. J. van Winkelhoff
CLINICAL ORAL IMPLANTS RESEARCH
(2015)
Article
Dentistry, Oral Surgery & Medicine
Yvonne C. M. y de Waal, Edwin G. Winkel, Gerwin C. Raangs, Marleen L. van der Vusse, John W. A. Rossen, Arie Jan van Winkelhoff
JOURNAL OF CLINICAL PERIODONTOLOGY
(2014)
Article
Dentistry, Oral Surgery & Medicine
Henny J. A. Meijer, Gerry M. Raghoebar, Yvonne C. M. de Waal, Arjan Vissink
JOURNAL OF CLINICAL PERIODONTOLOGY
(2014)
Review
Dentistry, Oral Surgery & Medicine
Yvonne C. de Waal, Edwin G. Winkel, Henny J. Meijer, Gerry M. Raghoebar, Arie J. van Winkelhoff
JOURNAL OF PERIODONTOLOGY
(2014)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Arie Jan Van Winkelhoff, Gerry M. Raghoebar, Henny J. A. Meijer
INTERNATIONAL JOURNAL OF PROSTHODONTICS
(2020)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Arie Jan Van Winkelhoff, Henny J. A. Meijer, Gerry M. Raghoebar
INTERNATIONAL JOURNAL OF DENTAL HYGIENE
(2020)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Arjan Vissink, Arie Jan Van Winkelhoff, Henny J. A. Meijer, Sylvia C. Liefers, Frans G. M. Kroese, Gerry M. Raghoebar
Summary: Implants with peri-implantitis have higher levels of IL-1beta and MMP-8 in peri-implant crevicular fluid compared to healthy implants. Non-surgical treatment did not improve biomarker levels, with IL-1beta and MMP-8 remaining high post-treatment. No differences were found in levels of other biomarkers between healthy and diseased implants.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Roy E. Stewart, Arie Jan Van Winkelhoff, Henny J. A. Meijer, Gerry M. Raghoebar
Summary: The study compared the effect of erythritol air polishing and piezoelectric ultrasonic scaling in the non-surgical treatment of peri-implantitis. Results showed no significant difference in treatment outcomes at 3 months, but a majority of patients still required further surgical treatment.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yvonne C. M. De Waal, Tine E. Vangsted, Arie Jan Van Winkelhoff
Summary: The study found that the adjunctive use of AMX and MTZ antibiotics did not significantly improve the clinical and microbiological outcomes of non-surgical treatment for peri-implantitis. Meticulously performed full-mouth non-surgical treatment and maintaining high levels of oral hygiene are crucial for the initial phase of subsequent peri-implantitis treatment.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Roy E. Stewart, Arie Jan Van Winkelhoff, Henny J. A. Meijer, Gerry M. Raghoebar
Summary: This study compared erythritol air polishing with saline cleansing of implant surfaces during surgical treatment of peri-implantitis. The results showed no significant differences between the two methods in terms of bleeding on probing, plaque score, probing pocket depth, and marginal bone loss, but a significant difference was found in suppuration on probing. Both methods resulted in low treatment success rates.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Hans Strooker, Yvonne Catharina Maria de Waal, Miriam Margot Bildt
Summary: The aim of this study was to evaluate the association between peri-implantitis and psychological distress, as well as potential related/mediating factors. The results showed that depressive symptoms were significantly associated with peri-implantitis.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Yvonne C. M. de Waal, Lewis Winning, Andreas Stavropoulos, Ioannis Polyzois
Summary: Adjunctive chemical approaches for implant surface decontamination may offer an advantage over sub-marginal instrumentation alone, in terms of improved probing depth. However, the effects on other outcome variables were inconsistent or showed no differences.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Diederik F. M. Hentenaar, Yvonne C. M. De Waal, Hans Strooker, Henny J. A. Meijer, Arie-Jan Van Winkelhoff, Gerry M. Raghoebar
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
(2017)