Article
Nutrition & Dietetics
Maria Minter, Hanna Augustin, Jenny van Odijk, Lowie E. G. W. Vanfleteren
Summary: This study aimed to assess vitamin D status and determinants of vitamin D insufficiency in patients with COPD in Southwestern Sweden. The results showed that vitamin D insufficiency is common in patients with COPD and is related to male gender, smoking habits, lack of supplements containing vitamin D, and the winter season for blood sampling.
Article
Endocrinology & Metabolism
Hanyuan Xu, Guiyan Han, Linjie Wang, Huihua Ding, Chunyan Wang, Xiaochuan Ping, Caixia Dong, Dianxi Zhang, Yufei Dai, Naishi Li, Yufeng Li, Hongbo Yang, Huijuan Zhu, Hui Pan, Fengying Gong, Jichun Chen, Xiaoping Xing
Summary: This study investigated the relationship between serum 25(OH)D levels and MetS risk in a cohort of middle-aged Chinese subjects. The results showed that MetS patients had lower 25(OH)D levels, which were inversely associated with metabolic dysfunctions. With 1-year diet and exercise counselling, the metabolic status of MetS patients significantly improved along with elevated 25(OH)D levels.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Hansjorg Baurecht, Michael Nolde, Thomas Kocher, Birte Holtfreter, Benjamin Ehmke, Anke Hannemann
Summary: Using Mendelian randomization, this study found no significant association between genetically proxied 25OHD and periodontitis risk. Although there was a correlation at the genetic level, the effect of 25OHD levels on the risk of periodontitis appears to be minimal.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fangjing Zhou, Ning Ma, Ruiting Su, Xiaoyu He, Xiaona Wang, Yang Zhou, Jing Shi
Summary: This study explored the relationship between serum 25 (OH)D and severe periodontitis using data from 2928 participants. The results revealed a nonlinear association between serum 25 (OH)D and severe periodontitis, with a negative correlation observed when serum 25 (OH)D levels were less than 102 nmol/L. Subgroup analysis showed significant changes in non-Hispanic white, alcohol consumption, diabetes, and health insurance.
Article
Pediatrics
Simei Wang, Quanmei Xu, Anqi Wang, Fang Yuan, Xiaona Luo, Yilin Wang, Miao Guo, Yuanfeng Zhang, Wenjing Zhang, Xiaobing Ji, Yun Ren, Yucai Chen
Summary: This study found a correlation between 25-hydroxyvitamin D deficiency and tic disorders (TD) in Chinese children, but no correlation between 25-hydroxyvitamin D deficiency and the severity of TD. Additionally, the deficiency of 25-hydroxyvitamin D was most pronounced in children over the age of 9.
FRONTIERS IN PEDIATRICS
(2022)
Article
Chemistry, Multidisciplinary
Anna Carrera-Cortes, Yuliana Pascual-Gonzalez, Salud Santos, Jenifer Martin-Gonzalez, Juan Jose Segura-Egea, Jose Lopez-Lopez
Summary: This case-control study aimed to investigate the association between COPD and Apical Periodontitis (AP). The results showed no significant difference in PAI>=3 between COPD patients and non-COPD patients, but COPD patients tend to have more teeth with PAI>=3, require more endodontic treatments, and have higher accumulation of caries in their periodontitis.
APPLIED SCIENCES-BASEL
(2022)
Review
Medicine, General & Internal
Stephanie A. Christenson, Benjamin M. Smith, Mona Bafadhel, Nirupama Putcha
Summary: Chronic obstructive pulmonary disease (COPD) is a global health problem that leads to high morbidity, mortality, and healthcare utilization. Its main causes are exposure to harmful particles, such as tobacco smoke and pollutants. Recent research has shown that various factors throughout the life course increase the risk of developing COPD. Innovations in omics and imaging techniques have provided greater understanding of the disease's pathophysiology, potentially leading to advancements in its prevention, diagnosis, and treatment. This review focuses on recent advances in the epidemiology, pathophysiology, imaging, diagnosis, and treatment of COPD.
Article
Biochemistry & Molecular Biology
Shufei Zeng, Chang Chu, Cornelia Doebis, Volker von Baehr, Berthold Hocher
Summary: There is a strong positive linear correlation between free 25(OH)D (f25(OH)D) and total 25(OH)D, making them useful for assessing vitamin D levels. The recommended threshold level for f25(OH)D is 8.499 pg/mL, corresponding to a target concentration of at least 30 ng/mL for t25(OH)D. The upper limit for vitamin D is still unclear, with most experts favoring a upper limit of 100 ng/mL for t25(OH)D.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Genetics & Heredity
Shuqin Liu, Yun Fu, Dirk Ziebolz, Simin Li, Gerhard Schmalz, Fan Li
Summary: This study identified EPB41L4A-AS1, INSR, and R3HDM1 as potential crosstalk genes between COPD and periodontitis. R3HDM was positively correlated with Th1 cells in both diseases, while INSR was positively correlated with Hepatocytes in periodontitis and COPD, supporting a potential pathophysiological relationship between periodontitis and COPD.
BMC MEDICAL GENOMICS
(2022)
Article
Nutrition & Dietetics
Jun-Hyuk Lee, Yu-Jin Kwon, Hye Sun Lee, Jee Hye Han, Boyoung Joung, Sung Jin Kim
Summary: This study confirms an inverse dose-dependent association between serum 25-hydroxyvitamin D levels and elevated intraocular pressure (EIOP) in a large sample of 15,338 individuals. Each unit increase in serum 25-hydroxyvitamin D is associated with a 3% decrease in the odds of having EIOP. Compared to individuals deficient in 25-hydroxyvitamin D, those with insufficiency and sufficiency have a 28% and 49% lower odds of EIOP, respectively. Therefore, clinical assessment of intraocular pressure may be helpful in the treatment and prevention of glaucoma in patients with insufficient 25-hydroxyvitamin D.
Article
Multidisciplinary Sciences
Einar M. H. Martinsen, Tomas M. L. Eagan, Elise O. Leiten, Ingvild Haaland, Gunnar R. Husebo, Kristel S. Knudsen, Christine Drengenes, Walter Sanseverino, Andreu Paytuvi-Gallart, Rune Nielsen
Summary: The study revealed differences in taxonomic composition and diversity between oral and pulmonary mycobiomes in participants with COPD and controls, with more Candida found in oral samples. Malassezia and Sarocladium were frequently found in pulmonary samples. There were no consistent differences in terms of differential abundance/distribution between study groups, but sample type affected beta diversity.
Article
Nutrition & Dietetics
RuTong Wang, Weijing Wang, Ping Hu, Ronghui Zhang, Xue Dong, Dongfeng Zhang
Summary: This study aimed to evaluate the association between dietary vitamin D intake and serum vitamin D concentrations with cognitive performance in older Americans. The results showed a positive association between dietary vitamin D intake, serum total 25-hydroxyvitamin D, and cognitive performance, with no significant gender differences in the associations. Further research is needed to clarify the effects of dietary vitamin D intake and specific serum D concentrations on cognitive performance.
Article
Nutrition & Dietetics
Berenice Rivera-Paredez, Alberto Hidalgo-Bravo, Guadalupe Leon-Reyes, Leith S. Leon-Maldonado, Arnoldo Aquino-Galvez, Manuel Castillejos-Lopez, Edgar Denova-Gutierrez, Yvonne N. Flores, Jorge Salmeron, Rafael Velazquez-Cruz
Summary: This study evaluated the association between 25(OH)D (total, free, and bioavailable) with adiposity and metabolic traits. The findings suggest that free and bioavailable 25(OH)D do not offer additional advantages over total 25(OH)D regarding its association with adiposity and several metabolic traits in Mexican adults.
Article
Nutrition & Dietetics
Xiaoyun Shan, Yang Cao, Huidi Zhang, Xiayu Zhao, Siran Li, Yichun Hu, Lichen Yang
Summary: The study found that free and bioavailable 25(OH)D correlated well with total 25(OH)D, but only had a threshold effect on P1NP. A total 25(OH)D of < 15.14 ng/mL was marginally associated with a higher risk of reduced HDL-C. Higher levels of free and bioavailable 25(OH)D were associated with a lower risk of reduced HDL-C. PTH and BTMs responded more sensitively to changes in total 25(OH)D than to free or bioavailable 25(OH)D after vitamin D supplementation in Chinese women of childbearing age.
FRONTIERS IN NUTRITION
(2023)
Article
Endocrinology & Metabolism
Suyan Duan, Fang Lu, Buyun Wu, Chengning Zhang, Guangyan Nie, Lianqin Sun, Zhimin Huang, Honglei Guo, Bo Zhang, Changying Xing, Yanggang Yuan
Summary: This study found that decreased levels of 25-hydroxyvitamin D (25(OH)D) in patients with type 2 diabetes mellitus (T2DM) were associated with deteriorated renal function and increased risk of chronic kidney disease (CKD) progression.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yu Yang, Jinsong Guo, Xuan Zhou, Zhiqiang Liu, Chenbao Wang, Kaile Wang, Jue Zhang, Zuomin Wang
DENTAL MATERIALS JOURNAL
(2018)
Article
Dentistry, Oral Surgery & Medicine
Zhiqiang Liu, Wei Zhang, Jing Zhang, Xuan Zhou, Liangqiong Zhang, Yiqing Song, Zuomin Wang
JOURNAL OF CLINICAL PERIODONTOLOGY
(2012)
Article
Dentistry, Oral Surgery & Medicine
Xuan Zhou, Jing Han, Zhiqiang Liu, Yiqing Song, Zuomin Wang, Zheng Sun
JOURNAL OF CLINICAL PERIODONTOLOGY
(2014)
Article
Dentistry, Oral Surgery & Medicine
Yan Si, Hong Fan, Yiqing Song, Xuan Zhou, Jing Zhang, Zuomin Wang
JOURNAL OF PERIODONTOLOGY
(2012)
Article
Dentistry, Oral Surgery & Medicine
Qian Zhao, Shi-Bin Wang, Guodong Xu, Yiqing Song, Xiaozhe Han, Zhiqiang Liu, Xuan Zhou, Tianyi Zhang, Kewu Huang, Ting Yang, Yingxiang Lin, Sinan Wu, Zuomin Wang, Chen Wang
JOURNAL OF CLINICAL PERIODONTOLOGY
(2019)
Article
Endocrinology & Metabolism
Dongxue Zhang, Wenyan Liu, Ran Miao, Lei Wang, Xuan Zhou, Haiyan Wang, Yufeng Li, Zuomin Wang
Summary: This study found that patients with periodontitis in type 2 diabetes mellitus may be more susceptible to decreased kidney function. Those with severe periodontitis had higher levels of HbA1c. Patients with renal dysfunction had worse periodontal conditions and higher pocket probing depth.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
(2021)
Article
Dentistry, Oral Surgery & Medicine
Xuan Zhou, Mei Lin, Dongxue Zhang, Yiqing Song, Zuomin Wang
JOURNAL OF CLINICAL PERIODONTOLOGY
(2019)
Article
Dentistry, Oral Surgery & Medicine
Weimin Gao, Huilin Tang, Danyang Wang, Xuan Zhou, Yiqing Song, Zuomin Wang
JOURNAL OF PERIODONTAL RESEARCH
(2020)
Article
Respiratory System
Xuan Zhou, Jitian Wang, Wenyan Liu, Xuan Huang, Yiqing Song, Zuomin Wang, Xingyuan Jia
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2020)
Article
Immunology
Zhiqiang Liu, Xiaoli Gao, Lirong Liang, Xuan Zhou, Xiaozhe Han, Ting Yang, Kewu Huang, Yingxiang Lin, Shu Deng, Zuomin Wang, Chen Wang
Summary: The purpose of this study was to assess the prevalence and identify the risk factors of gastroesophageal reflux disease (GERD) in the Chinese adult population. Data from a nationally representative sample of Chinese adults were collected, and the overall prevalence of GERD was found to be 5.6%. Women, smokers, older individuals, those with higher BMI, urban residents, individuals with lower education level or comorbidities were more likely to have GERD. Symptoms of severe periodontitis and lower frequency of tooth brushing were significantly associated with the risk of GERD.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Article
Respiratory System
Zhiqiang Liu, Xuan Zhou, Lirong Liang, Xiaozhe Han, Ting Yang, Kewu Huang, Yingxiang Lin, Zuomin Wang, Chen Wang
Summary: This study aimed to determine the association between symptoms of severe periodontitis (SSP) and post-bronchodilator lung function in the Chinese population. The results showed that participants with SSP had significantly lower post-bronchodilator lung function values compared to those without SSP. After adjusting for potential confounders, SSP remained negatively associated with post-bronchodilator lung function and significantly associated with a post-bronchodilator lung function value below 0.7.
BMC PULMONARY MEDICINE
(2023)