Non-alcoholic fatty liver disease: non-invasive investigation and risk stratification

Are simple noninvasive scoring systems for fibrosis reliable in patients with NAFLD and normal ALT levels?

(2013) Stuart McPherson et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers

(2012) J. Shen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Cholesterol and nonalcoholic fatty liver disease: Renewed focus on an old villain

(2012) Thomas A. Kerr et al.   HEPATOLOGY

Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

(2012) Pierre Bedossa et al.   HEPATOLOGY

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease

(2012) Sudeep Tanwar et al.   HEPATOLOGY

Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography

(2012) Robert P. Myers et al.   LIVER INTERNATIONAL

Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD

(2012) Stefano Ballestri et al.   LIVER INTERNATIONAL

Performance of Biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in Patients with Severe Obesity: Meta Analysis of Individual Patient Data

(2012) Thierry Poynard et al.   PLoS One

Genetic modifiers of non-alcoholic fatty liver disease progression

(2011) Quentin M. Anstee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Prevalence of and Risk Factors for Hepatic Steatosis and Nonalcoholic Fatty Liver Disease in People With Type 2 Diabetes: the Edinburgh Type 2 Diabetes Study

(2011) R. M. Williamson et al.   DIABETES CARE

Validation of noninvasive biomarkers (FibroTest, SteatoTest, and NashTest) for prediction of liver injury in patients with morbid obesity

(2011) Guillaume Lassailly et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Mortality in nonalcoholic fatty liver disease: Clues from the cremona study

(2011) Leon A. Adams   HEPATOLOGY

Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients

(2011) Robert P. Myers et al.   HEPATOLOGY

Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease

(2011) Kris V. Kowdley et al.   HEPATOLOGY

A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis

(2011) Vlad Ratziu et al.   HEPATOLOGY

Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis

(2011) Diana Joka et al.   HEPATOLOGY

Pathologic criteria for nonalcoholic steatohepatitis: Interprotocol agreement and ability to predict liver-related mortality

(2011) Zobair M. Younossi et al.   HEPATOLOGY

Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network

(2011) Raj Vuppalanchi et al.   Hepatology International

Noninvasive evaluation of hepatic fibrosis using acoustic radiation force-based shear stiffness in patients with nonalcoholic fatty liver disease

(2011) Mark L. Palmeri et al.   JOURNAL OF HEPATOLOGY

Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe

(2011) Robert P. Myers et al.   JOURNAL OF HEPATOLOGY

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies

(2011) Ahmad Al-Serri et al.   JOURNAL OF HEPATOLOGY

Novel controlled attenuation parameter for noninvasive assessment of steatosis using Fibroscan®: validation in chronic hepatitis C

(2011) M. Sasso et al.   JOURNAL OF VIRAL HEPATITIS

Serum ferritin is a discriminant marker for both fibrosis and inflammation in histologically proven non-alcoholic fatty liver disease patients

(2011) Pinelopi Manousou et al.   LIVER INTERNATIONAL

Early Detection of Nonalcoholic Steatohepatitis in Patients with Nonalcoholic Fatty Liver Disease by Using MR Elastography

(2011) Jun Chen et al.   RADIOLOGY

Low clinical relevance of the nonalcoholic fatty liver disease activity score (NAS) in predicting fibrosis progression

(2011) Mattias Ekstedt et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin-18 for the diagnosis of non-alcoholic steatohepatitis in morbidly obese patients

(2010) R. Anty et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity

(2010) Giovanni Musso et al.   ANNALS OF MEDICINE

A simple index of lipid overaccumulation is a good marker of liver steatosis

(2010) Giorgio Bedogni et al.   BMC GASTROENTEROLOGY

Noninvasive liver steatosis quantification using MRI techniques combined with blood markers

(2010) Elodie Cesbron-Métivier et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study

(2010) Christopher D. Williams et al.   GASTROENTEROLOGY

Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease

(2010) S. McPherson et al.   GUT

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

Is oil red-O staining and digital image analysis the gold standard for quantifying steatosis in the liver?

(2010) Adam P. Levene et al.   HEPATOLOGY

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

Which Clinical and Sonographic Parameters May Be Useful to Discriminate NASH from Steatosis?

(2010) Enrico Maria Zardi et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Non-invasive diagnosis of nonalcoholic fatty liver and nonalcoholic steatohepatitis

(2010) Leon A ADAMS et al.   Journal of Digestive Diseases

Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis

(2010) Quentin M. Anstee et al.   JOURNAL OF HEPATOLOGY

A position statement on NAFLD/NASH based on the EASL 2009 special conference

(2010) Vlad Ratziu et al.   JOURNAL OF HEPATOLOGY

EASL clinical practice guidelines for HFE hemochromatosis

(2010)   JOURNAL OF HEPATOLOGY

An apoptosis panel for nonalcoholic steatohepatitis diagnosis

(2010) Tarek I. Abu-Rajab Tamimi et al.   JOURNAL OF HEPATOLOGY

A Biomarker Panel for Non-alcoholic Steatohepatitis (NASH) and NASH-Related Fibrosis

(2010) Zobair M. Younossi et al.   OBESITY SURGERY

Nonalcoholic Fatty Liver Disease: US-based Acoustic Radiation Force Impulse Elastography

(2010) Masato Yoneda et al.   RADIOLOGY

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Comparison of Noninvasive Markers of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

(2009) Amy G. Shah et al.   Clinical Gastroenterology and Hepatology

Epidemiology and Natural History of Non-Alcoholic Steatohepatitis

(2009) Curtis K. Argo et al.   Clinics in Liver Disease

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

(2009) K. Kantartzis et al.   DIABETES

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Prediction of Non-Alcoholic Fatty Liver Disease and Liver Fat Using Metabolic and Genetic Factors

(2009) Anna Kotronen et al.   GASTROENTEROLOGY

Noninvasive assessment of liver disease severity with liver fat score and CK-18 in NAFLD: Prognostic value of liver fat equation goes beyond hepatic fat estimation

(2009) Giovanni Musso et al.   HEPATOLOGY

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: A multicenter validation study

(2009) Ariel E. Feldstein et al.   HEPATOLOGY

Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease

(2009) Vincent Wai-Sun Wong et al.   HEPATOLOGY

Diagnostic value of a group of biochemical markers of liver fibrosis in patients with non-alcoholic steatohepatitis

(2009) C. Rinaldi A. LESMANA et al.   Journal of Digestive Diseases

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression

(2009) Geoffrey C Farrell et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Magnetic resonance imaging and spectroscopy accurately estimate the severity of steatosis provided the stage of fibrosis is considered

(2009) Stuart McPherson et al.   JOURNAL OF HEPATOLOGY

Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance

(2009) Nina F. Schwenzer et al.   JOURNAL OF HEPATOLOGY

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

(2009) Silvia Sookoian et al.   JOURNAL OF LIPID RESEARCH

Serum adipokine levels predictive of liver injury in non-alcoholic fatty liver disease

(2009) Maud Lemoine et al.   LIVER INTERNATIONAL

The Kruppel-Like Factor 6 Genotype Is Associated With Fibrosis in Nonalcoholic Fatty Liver Disease

(2008) Luca Miele et al.   GASTROENTEROLOGY

Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease

(2008) S A Harrison et al.   GUT

Comparison of blood tests for liver fibrosis specific or not to NAFLD

(2008) Paul Calès et al.   JOURNAL OF HEPATOLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

A “Biomarker Biopsy” for the Diagnosis of NASH: Promises from CK-18 Fragments

(2008) Yusuf Yilmaz et al.   OBESITY SURGERY

The Utility of the “NAFLD Fibrosis Score” in Morbidly Obese Subjects with NAFLD

(2008) Kamran Qureshi et al.   OBESITY SURGERY

A Novel Diagnostic Biomarker Panel for Obesity-related Nonalcoholic Steatohepatitis (NASH)

(2008) Zobair M. Younossi et al.   OBESITY SURGERY

High Prevalence of Small Intestinal Bacterial Overgrowth in Patients with Morbid Obesity: A Contributor to Severe Hepatic Steatosis

(2008) Jean-Marc Sabaté et al.   OBESITY SURGERY

Quantification of Liver Fat Content: Comparison of Triple-Echo Chemical Shift Gradient-Echo Imaging and in Vivo Proton MR Spectroscopy

(2008) Boris Guiu et al.   RADIOLOGY

Alcohol consumption is associated with progression of hepatic fibrosis in non-alcoholic fatty liver disease

(2008) Mattias Ekstedt et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY