Opiate Pharmacology and Relief of Pain

Efficacy and ligand bias at the μ-opioid receptor

(2013) E Kelly   BRITISH JOURNAL OF PHARMACOLOGY

Methadone-Induced Hypoglycemia

(2013) Andrew J. Faskowitz et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Stabilization of the μ-Opioid Receptor by Truncated Single Transmembrane Splice Variants through a Chaperone-like Action

(2013) Jin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and Evaluation of Aryl-Naloxamide Opiate Analgesics Targeting Truncated Exon 11-Associated μ Opioid Receptor (MOR-1) Splice Variants

(2012) Susruta Majumdar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

(2011) Eric Reiter et al.   Annual Review of Pharmacology and Toxicology

Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation

(2011) Chad E. Groer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Selectivity at the  -Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance

(2011) K. M. Raehal et al.   PHARMACOLOGICAL REVIEWS

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

(2011) S. Majumdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishing “Best Practices” for Opioid Rotation: Conclusions of an Expert Panel

(2009) Perry G. Fine et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

(2009) Y.-X. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herkinorin Analogues with Differential β-Arrestin-2 Interactions

(2008) Kevin Tidgewell et al.   JOURNAL OF MEDICINAL CHEMISTRY

(244) Symptomatic hypoglycemia due to escalating doses of intravenous methadone

(2008) S. Maingi et al.   JOURNAL OF PAIN