Transcription Factor STAT3 As a Prognostic Marker and Therapeutic Target in Cancer

Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma

(2013) C Gordziel et al.   BRITISH JOURNAL OF CANCER

STAT3 expression correlates with prognosis of thymic epithelial tumors

(2013) Chao Li et al.   Journal of Cardiothoracic Surgery

Activation of the STAT3 Signaling Pathway Is Associated With Poor Survival in Diffuse Large B-Cell Lymphoma Treated With R-CHOP

(2013) Xin Huang et al.   JOURNAL OF CLINICAL ONCOLOGY

Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis

(2012) Amir Sonnenblick et al.   Clinical & Translational Oncology

Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer

(2012) Hua Xiong et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

STAT3 negatively regulates thyroid tumorigenesis

(2012) J. P. Couto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy

(2012) Malabika Sen et al.   Cancer Discovery

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Reciprocal Effects of STAT5 and STAT3 in Breast Cancer

(2009) S. R. Walker et al.   MOLECULAR CANCER RESEARCH

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

(2008) N. de la Iglesia et al.   GENES & DEVELOPMENT