Article
Oncology
Mahmoud Al-Masri, Fade Alawneh, Faiez Daoud, Ali Ebous, Basem Hamdan, Hani Al-Najjar, Rama Al-Masri, Marwan Abu Farah
Summary: The study aimed to assess the effect of Cyanoacrylate on reducing seroma formation in breast cancer patients undergoing axillary dissection. The results showed that Cyanoacrylate did not decrease seroma formation and was not cost-effective. Higher seroma volume was associated with modified radical mastectomy, older age, and higher BMI.
FRONTIERS IN ONCOLOGY
(2021)
Article
Surgery
Filipe Basile, Thais S. Oliveira
Summary: Early exercise after breast augmentation surgery does not increase complications or reoperation rates, and does not cause a reduction in scar quality. In addition, patient-reported outcomes show improvement in the exercise group.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Oncology
Tsae-Jyy Wang, Pei-Pei Chiu, Kuang-Kuo Chen, Lun-Ping Hung
Summary: The study found that the decision support intervention significantly reduced patients' decisional conflict, while improving their knowledge and self-efficacy. However, the intervention did not affect patients' biopsy decision.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2021)
Article
Oncology
Shi-Qian Lin, Chih-Ming Su, Hsueh-Chi Wu, Yun-Yun Chou, Yu-Chun Yen, Ka-Wai Tam
Summary: PDAs did not assist patients with breast cancer in making surgical treatment decisions, highlighting the need for clinicians to focus on evidence-based medicine and help patients consider their individual preferences in shared decision-making.
Article
Chemistry, Medicinal
Mengyue Fu, Shi Chen, Rui Xu, Jie Chen, Xuehan Chen, Wanxia Gan, He Huang, Guangyou Duan
Summary: This study aimed to explore the effects of intravenous analgesia using tramadol on postoperative depression, anxiety, and sleep in women undergoing abdominal endoscopic surgery. The results showed that intravenous analgesia with tramadol can effectively improve postoperative depression and sleep, with no impact on anxiety state.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Oncology
Marie-Anne Durand, Renata W. Yen, A. James O'Malley, Danielle Schubbe, Mary C. Politi, Catherine H. Saunders, Shubhada Dhage, Kari Rosenkranz, Julie Margenthaler, Anna N. A. Tosteson, Eloise Crayton, Sherrill Jackson, Ann Bradley, Linda Walling, Christine M. Marx, Robert J. Volk, Karen Sepucha, Elissa Ozanne, Sanja Percac-Lima, Emily Bergin, Courtney Goodwin, Caity Miller, Camille Harris, Richard J. Barth, Rebecca Aft, Sheldon Feldman, Amy E. Cyr, Christina V. Angeles, Shuai Jiang, Glyn Elwyn
Summary: Women of lower socioeconomic status with early-stage breast cancer may face communication challenges and lower satisfaction with surgery compared to those with higher SES. This study aimed to support women in making breast cancer surgery choices across different socioeconomic strata. Using conversation aids with pictures and text improved knowledge, decision process, shared decision making, and decision regret, especially among disadvantaged patients. Text-only conversation aids also led to improvements in decision process, coordinated care, and shared decision making compared to usual care.
Article
Anesthesiology
Marcus A. Bachhuber, Denis Nash, William N. Southern, Moonseong Heo, Matthew Berger, Mark Schepis, Olivia K. Sugarman, Chinazo O. Cunningham
Summary: The study found that reducing the default dispense quantity can effectively reduce the quantity of opioid analgesics prescribed in dentistry practices. However, caution is needed in choosing the default value.
Article
Public, Environmental & Occupational Health
Pei-Shan Tsai, Chih-Chien Wang, Yi-Hsuan Lan, Han-Wei Tsai, Chin-Yin Hsiao, Jeng-Cheng Wu, Shyr-Ming Sheen-Chen, Wen-Hsuan Hou
Summary: The effectiveness of a question prompt list (QPL) in improving decision self-efficacy, patient-physician communication, and perceived patient-physician interactions among breast cancer patients was evaluated. The QPL intervention showed significant improvements compared to routine care, suggesting its potential value in clinical practice.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Public, Environmental & Occupational Health
Guofang Ye, Bo Qu, Yih-Chung Tham, Yuxin Zhong, Ling Jin, Ecosse Lamoureux, Nathan Congdon, Yingfeng Zheng, Yizhi Liu
Summary: The study found that using a patient decision aid can increase the proportion of patients making informed choices, improve their overall knowledge about cataract surgery, and reduce the intention to undergo surgery.
PATIENT EDUCATION AND COUNSELING
(2021)
Article
Medicine, General & Internal
Mei-Chi Hsu, Wen-Chen Ouyang
Summary: Moral cognition is an important determinant of violence, but it is often overlooked. Few interventions have examined the combined effects of moral reasoning, anger management, and problem-solving on violence. A randomized controlled trial evaluated the sustained effects of an integrated Moral Reasoning Development Intervention (MRDI) on repetitive violence in schizophrenia. MRDI improved moral reasoning and decreased violent behaviors in patients with schizophrenia, suggesting its potential for risk assessment and violence management.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
Arushi Gulati, Hasan Abdulbaki, Jacquelyn K. Callander, Yi Cai, Jolie L. Chang
Summary: Patients with obstructive sleep apnea (OSA) have high levels of decisional conflict (DC) when considering positive airway pressure (PAP) alternatives. The use of video decision aids prior to sleep surgery consultation may improve the treatment decision-making process.
Article
Surgery
Martin Sollie, Navid M. Toyserkani, Camilla Bille, Jorn Bo Thomsen, Jens Ahm Sorensen
Summary: This study compared the effects of fat grafting and a sham operation in treating postmastectomy pain syndrome. The results showed that fat grafting did not demonstrate superior effects over a placebo.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Medicine, General & Internal
Sander S. J. Schop, Juliette E. Hommes, Todor K. Krastev, Danielle Derks, Mikko Larsen, HInne Rakhorst, Ute Schmidbauer, Jan Maerten Smit, Tik Tan, Kim Wehrens, Thijs de Wit, Rene R. W. J. van der Hulst, Andrzej A. Piatkowski de Grzymala
Summary: This study is a multicenter randomized controlled clinical trial investigating the effectiveness of AFT for breast reconstruction, with quality of life measured by the BREAST-Q questionnaire. Approval was obtained from the ethics committee and results will be disseminated through scientific meetings and peer-reviewed journals.
Article
Surgery
Samiullah Bhatti, Yusra Jahangir Malik, Shabbar Hussain Changazi, Usman Ali Rahman, Awais Amjad Malik, Usman Ismat Butt, Muhammad Umar, Muhammad Waris Farooka, Mahmood Ayyaz
Summary: This study conducted a single-blinded, randomized clinical trial to determine the effectiveness of chewing gum in reducing postoperative ileus, showing that chewing gum after the reversal of ileostomy significantly shortens the time to passage of flatus and length of hospital stay.
WORLD JOURNAL OF SURGERY
(2021)
Article
Clinical Neurology
Benjamin D. Wissel, Hansel M. Greiner, Tracy A. Glauser, Francesco T. Mangano, Katherine D. Holland-Bouley, Nanhua Zhang, Rhonda D. Szczesniak, Daniel Santel, John P. Pestian, Judith W. Dexheimer
Summary: A randomized controlled trial using a clinical decision support system embedded in the electronic health record showed that automated electronic alerts increased referrals for epilepsy surgery evaluations.
Review
Oncology
Vivian Man, Wing-Pan Luk, Ling-Hiu Fung, Ava Kwong
Summary: Recent studies have shown that a significant proportion of breast cancer patients who underwent pre-operative axillary ultrasound (AUS) and needle biopsy were over-treated with axillary lymph node dissection (ALND). The role of routine AUS and needle biopsy in early breast cancer has been questioned. This review aims to determine if pre-operative AUS can predict the extent of axillary tumor burden and the need for ALND.
BREAST CANCER RESEARCH AND TREATMENT
(2022)
Review
Oncology
Michael Co, Lucia Lam, Dacita Suen, Ava Kwong
Summary: This article is a systematic review of randomized controlled trials comparing the use of axillary reverse mapping (ARM) with conventional technique for axillary dissection (AD) in breast cancer surgery. The results showed that patients in the ARM group had a lower incidence of post-operative lymphedema, and there was no significant difference in axillary recurrence rate compared to the AD group.
CLINICAL BREAST CANCER
(2022)
Article
Oncology
Youngmee Kim, Amanda Ting, Charles S. Carver, Ozan Bahcivan, Cristiane Decat Bergerot, Degi Csaba, Tania Estape, Daisuke Fujisawa, Savita S. Goswami, Wendy Wing Tak Lam, Andrada Parvu, Eun-Jung Shim, Samantha Serpentini, Emi Takeuchi, Ashley Wang
Summary: This study aimed to evaluate healthcare professionals' assessment of unmet needs of cancer patients and family caregivers globally. The results showed that emotional distress and medical care needs were the most common concerns, yet less than two-thirds of healthcare professionals reported that their institutions provided services or programs to meet these needs.
Article
Oncology
Andreas Karakatsanis, Staffan Eriksson, Lida Pistiolis, Roger Olofsson Bagge, Gyula Nagy, Vivian Man, Ava Kwong, Fredrik Warnberg
Summary: This study demonstrates that marking the SLN with SPIO can avoid overtreatment and allow for accurate d-SLND in patients with DCIS. This is significant for the treatment of patients with DCIS.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Ava Kwong, Michael Co, Eisuke Fukuma
Summary: This study is a prospective single-arm clinical trial on cryosurgery for early breast cancers, evaluating the expanded criteria for tumors larger than 1.5 cm and non-luminal breast cancers. The results showed that residual cancer was found in 46.7% of patients, all of which were located at the periphery of the cryoablation zone. Careful pre-operative planning and intra-operative monitoring are crucial to ensure complete cryoablation.
CLINICAL BREAST CANCER
(2023)
Article
Medicine, General & Internal
Danielle Wing Lam Ng, Richard Fielding, Catherine Tsang, Carmen Ng, Joyce Chan, Amy Or, Izy Wing Man Kong, Julia Wei Chun Tang, Wylie Wai Yee Li, Amy Tien Yee Chang, Chi Choo Foo, Ava Kwong, Simon Siu-Man Ng, Dacita Suen, Miranda Chan, Oi-Kwan Chun, Karen Kar Loen Chan, Phyllis N. Butow, Wendy Wing Tak Lam
Summary: The purpose of this study is to evaluate the effectiveness of the Chinese version of the ConquerFear-HK intervention in improving fear of cancer recurrence. A randomized controlled trial will be conducted with 174 eligible Chinese cancer survivors who will be assigned to either the ConquerFear-HK or BasicCancerCare intervention. Various measures will be used to assess the intervention's effects and psychological impacts.
Editorial Material
Oncology
Vivian Man, Dacita Suen, Ava Kwong
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Vivian Man, Dacita Suen, Ava Kwong
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Vivian Man, Dacita Suen, Ava Kwong
Summary: The study compares the efficacy of superparamagnetic iron oxide (SPIO)-guided and standard techniques for detecting sentinel lymph nodes (SLN) in early breast cancer. Multiple inferiority trials have shown that SPIO is not inferior to conventional techniques in detecting SLNs. The results indicate that single-tracer SPIO-guided SLNB is as effective as the dual technique (radioisotope and blue dye) and can safely replace the gold standard for SLN mapping in early breast cancer.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Clinical Neurology
Julia Chan, Danielle Wing Lam Ng, Qiuyan Liao, Richard Fielding, Inda Soong, Karen Kar Loen Chan, Conrad Lee, Alice Wan Ying Ng, Wing Kin Sze, Wing Lok Chan, Victor Ho Fun Lee, Wendy Wing Tak Lam
Summary: The study aims to examine the trajectories of sleep disturbance in cancer survivors during the first 2 years post-treatment and to investigate whether psychological, cognitive, and physical factors differentiate these trajectories. The findings showed that one in three cancer survivors experienced persistent high sleep disturbance, with higher rates of intrusive thoughts and cancer-related hyperarousal compared to stable good sleepers. Higher depression scores also predicted membership in the persistent high sleep disturbance group.
Article
Oncology
Ava Kwong, Cecilia Y. S. Ho, Wing-Pan Luk, Ling-Hiu Fung, Chun-Hang Au, Edmond S. K. Ma
Summary: A study in the Chinese population found that the updated NCCN guidelines for the testing of breast cancer susceptibility genes had a positive effect on the detection rate of germline mutations. However, there is a need to carefully consider the balance between resources and outcomes.
Article
Oncology
Wendy Wing Tak Lam, Danielle W. L. Ng, Richard Fielding, Vivian Sin, Catherine Tsang, Wendy W. L. Chan, Chi Chung Foo, Ava Kwong, Karen K. L. Chan
Summary: This study evaluated the feasibility of a nurse-led symptom-screening program in routine oncology post-treatment outpatient clinics. The results showed that this program was acceptable and effective in reducing symptom distress, with a high acceptance rate for community-based psychosocial support services.
Meeting Abstract
Oncology
Ava Kwong, David Shao Peng Tan, Jai Min Ryu
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
Sarah Ward, Anya Burton, Rulla M. Tamimi, Ana Pereira, Maria Luisa Garmendia, Marina Pollan, Norman Boyd, Isabel dos-Santos-Silva, Gertraud Maskarinec, Beatriz Perez-Gomez, Celine Vachon, Hui Miao, Martin Lajous, Ruy Lopez-Ridaura, Kimberly Bertrand, Ava Kwong, Giske Ursin, Eunjung Lee, Huiyan Ma, Sarah Vinnicombe, Sue Moss, Steve Allen, Rose Ndumia, Sudhir Vinayak, Soo-Hwang Teo, Shivaani Mariapun, Beata Peplonska, Agnieszka Bukowska-Damska, Chisato Nagata, John Hopper, Graham Giles, Vahit Ozmen, Mustafa Erkin Aribal, Joachim Schuez, Carla H. Van Gils, Johanna O. P. Wanders, Reza Sirous, Mehri Sirous, John Hipwell, Jisun Kim, Jong Won Lee, Caroline Dickens, Mikael Hartman, Kee-Seng Chia, Christopher Scott, Anna M. Chiarelli, Linda Linton, Anath Arzee Flugelman, Dorria Salem, Rasha Kamal, Valerie McCormack, Jennifer Stone
Summary: Late age at menarche is positively associated with higher mammographic density, while taller stature is also related to higher mammographic density. The study reveals a complex relationship between growth and development, mammographic density, and breast cancer risk.
BREAST CANCER RESEARCH
(2022)
Article
Oncology
John Chi-Wang Ho, Jiawei Chen, Isabella Wai-Yin Cheuk, Man-Ting Siu, Vivian Yvonne Shin, Ava Kwong
Summary: In this study, the researchers investigated the effects of miR-199a-3p-mediated BRCA1 dysfunction on triple negative breast cancer (TNBC) progression and chemosensitivity. They found that miR-199a-3p directly targeted BRCA1 in TNBC cells, leading to its downregulation and inhibiting tumor growth. Moreover, miR-199a-3p reversed cisplatin resistance and sensitized TNBC cells to veliparib, potentially by repressing DNA repair ability and inducing cell apoptosis.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)