A strategic approach to the synthesis of functionalized spirooxindole pyrrolidine derivatives: in vitro antibacterial, antifungal, antimalarial and antitubercular studies

Synthesis and discovery of novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors

(2013) Yalda Kia et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line

(2013) Y. Arun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and QSAR studies of dispiroindole derivatives as new antiproliferative agents

(2013) Riham F. George et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An eco-compatible synthesis of medicinally important novel class of trispiroheterocyclic framework using 2,2,2-trifluoroethanol as a reusable medium

(2013) Anshu Dandia et al.   JOURNAL OF FLUORINE CHEMISTRY

Synthesis of Pyrrolo(spiro-[2.3′]-oxindole)-spiro-[4.3″]-oxindole via 1,3-Dipolar Cycloaddition of Azomethine Ylides with 3-Acetonylideneoxindole

(2013) Jun-An Xiao et al.   JOURNAL OF ORGANIC CHEMISTRY

A one-pot, three-component regiospecific synthesis of dispiropyrrolidines containing a thiophenone ring via 1,3-dipolar cycloaddition reactions of azomethine ylides

(2013) Firouz Matloubi Moghaddam et al.   TETRAHEDRON LETTERS

A strategic approach to the synthesis of novel class of dispiroheterocyclic derivatives through 1,3 dipolar cycloaddition of azomethine ylide with (E)-3-arylidene-2,3-dihydro-8-nitro-4-quinolone

(2013) Kumarasamy Chandraprakash et al.   TETRAHEDRON LETTERS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Recent developments in asymmetric multicomponent reactions

(2012) Corien de Graaff et al.   CHEMICAL SOCIETY REVIEWS

1,3-Dipolar Cycloaddition of Ethyl Diazoacetate with (E)-3-Arylidenechroman-4-ones. A New Access to Spirocyclopropane Derivatives

(2012) Kabula Ciamala et al.   HETEROCYCLES

Direct construction of novel exo′-selective spiropyrrolidine bisoxindoles via a three-component 1,3-dipolar cycloaddition reaction

(2012) Jie Liu et al.   TETRAHEDRON LETTERS

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The importance of Green Chemistry in Process Research and Development

(2011) Peter J. Dunn   CHEMICAL SOCIETY REVIEWS

A One-pot Green Synthesis of Alkylidenesuccinimides

(2011) Lin Yan et al.   CHINESE JOURNAL OF CHEMISTRY

An Efficient One Pot Synthesis of New Indanopyrazoline and Indanopyrazole Derivatives

(2011) Hanene Jelizi et al.   LETTERS IN ORGANIC CHEMISTRY

Characterization of the telomerization reaction path for vinylidene fluoride with ĊCl3radicals

(2011) Patrick Laflamme et al.   Polymer Chemistry

A facile and efficient ultrasound-assisted synthesis of novel dispiroheterocycles through 1,3-dipolar cycloaddition reactions

(2011) Yu Hu et al.   ULTRASONICS SONOCHEMISTRY

Substituted spiro [2.3′] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase

(2010) Mohamed Ashraf Ali et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A facile 1,3-dipolar cycloaddition of azomethine ylides to 2-arylidene-1,3-indanediones: Synthesis of dispiro-oxindolylpyrrolothiazoles and their antimycobacterial evaluation

(2010) Shanmugavel Uma Maheswari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide

(2010) Arumugam Thangamani   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regio- and Stereoselective 1,3-Dipolar Cycloaddition of C-Aryl-N-phenylnitrones over (E)-Arylidene-(2H)-indan-1-ones: Synthesis of Highly Substituted Novel Spiro-isoxazolidines

(2010) Mohamed El Baker Rammah et al.   HETEROCYCLES

A facile synthesis of chromeno[3,4-c]spiropyrrolidine-oxindoles via 1,3-dipolar cycloadditions

(2010) Mehdi Ghandi et al.   TETRAHEDRON

An experimental and theoretical investigation of the regio- and stereoselectivity of the polar [3+2] cycloaddition of azomethine ylides to nitrostyrenes

(2010) Kamal Alimohammadi et al.   TETRAHEDRON

Regio- and stereoselective synthesis of novel tetraspiro-bispyrrolidine and bisoxindolopyrrolidine derivatives through 1,3-dipolar cycloaddition reaction

(2010) R. Rajesh et al.   TETRAHEDRON LETTERS

Strategies for Innovation in Multicomponent Reaction Design

(2009) Bruce Ganem   ACCOUNTS OF CHEMICAL RESEARCH

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

A facile synthesis and antimycobacterial evaluation of novel spiro-pyrido-pyrrolizines and pyrrolidines

(2009) Raju Ranjith Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel three-component domino reactions of ketones, isatin and amino acids: Synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines

(2009) Raju Suresh Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens

(2008) Govindasami Periyasami et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regioselective synthesis of dispiro[1H-indene-2,3′-pyrrolidine-2′,3″-[3H]indole]-1,2″(1″H)-diones of potential anti-tumor properties

(2008) Adel S. Girgis   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological Intervention

(2008) Raju Ranjith Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY