Article
Medicine, General & Internal
Hyun Jin Lee, A. Reum Choe, HaeJu Lee, Dong Ryeol Ryu, Ea Wha Kang, Jung Tak Park, Su Hwan Lee, Junbeom Park
Summary: The rate of sudden cardiac death is significantly higher in hemodialysis patients, with QTpe interval and ECG parameters being potential predictors for predicting SCD risk in this population.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Behnam Noorani, Rajeev M. Menon, Xin Chen, Kennan C. Marsh, Weize Huang, Shelly Gupta, Edyta Dobkowska, Thomas Marbury, Ahmed Hamed Salem
Summary: This study demonstrates that end-stage renal disease (ESRD) and dialysis do not impact the pharmacokinetics of venetoclax, a Bcl-2 inhibitor. Therefore, no dose adjustment is needed for patients with renal insufficiency.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Infectious Diseases
Jose Molto, Fredzzia Graterol, Adrian Curran, Natalia Ramos, Arkaitz Imaz, Diego Sandoval, Francisco Perez, Lucia Bailon, Saye Khoo, Laura Else, Roger Paredes
Summary: This study evaluated the effect of haemodialysis on doravirine concentrations in people living with HIV (PLWH) undergoing routine haemodialysis. The results showed that despite moderate removal of doravirine by haemodialysis, trough doravirine concentrations in plasma after the haemodialysis sessions remained in excess of the protein-binding-adjusted EC50 (5 ng/mL). Therefore, doravirine dosage adjustments are unnecessary in PLWH undergoing intermittent haemodialysis.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Multidisciplinary Sciences
Chalani Lasanthika, Kamani Wanigasuriya, Usha Hettiaratchi, Thamara Dilhani Amarasekara, Christine Sampatha Evangeline Goonewardena, Surangi Jayakody
Summary: This study aimed to evaluate the psychometric properties of the Sinhalese version of the End Stage Renal Disease-Adherence Questionnaire (SINESRD-AQ) and assess treatment adherence behavior among hemodialysis patients in a Sri Lankan hospital. The study found that the SINESRD-AQ had excellent face and content validity, and demonstrated construct validity through confirmatory factor analysis. Test-retest reliability was also confirmed. The study concluded that the SINESRD-AQ is a valid and reliable measure for evaluating treatment adherence behavior among hemodialysis patients in Sri Lanka.
Article
Multidisciplinary Sciences
Kyung-Do Han, YouMi Hwang, Sang Hyun Park
Summary: This study evaluated the effect of differential blood pressure control on the prevalence of atrial fibrillation (AF) in patients with diabetic end-stage renal disease (ESRD). The results showed that the new onset hypertension, controlled hypertension, and uncontrolled hypertension groups had a higher risk of AF.
Article
Urology & Nephrology
Hannah M. L. Young, Nicki Ruddock, Mary Harrison, Samantha Goodliffe, Courtney J. Lightfoot, Juliette Mayes, Andrew C. Nixon, Sharlene A. Greenwood, Simon Conroy, Sally J. Singh, James O. Burton, Alice C. Smith, Helen Eborall
Summary: This study explores the lived experiences of frail adults receiving haemodialysis, finding that they face challenges at multiple levels, including individual, interpersonal, organizational, and societal levels. The findings suggest that implementing a holistic needs assessment, person-centred health and social care systems, greater family support, and enhancing opportunities for community participation may improve outcomes and experiences for these patients.
Article
Multidisciplinary Sciences
Min-Ling Lin, Kuei-Hui Chu
Summary: This study aimed to explore the experiences of urgent dialysis patients with end-stage renal disease. The results revealed that patients who delayed their treatment suffered severe complications. Health professionals play an important role in communication and coordination, and should assist patients in making decisions regarding dialysis treatment.
Article
Urology & Nephrology
Susana Coimbra, Susana Rocha, Henrique Nascimento, Maria Joao Valente, Cristina Catarino, Petronila Rocha-Pereira, Maria Sameiro-Faria, Jose Gerardo Oliveira, Jose Madureira, Joao Carlos Fernandes, Vasco Miranda, Luis Belo, Elsa Bronze-da-Rocha, Alice Santos-Silva
Summary: In ESRD patients on dialysis, high levels of cfDNA were associated with inflammation, anaemia, oxidative stress, and haemostatic disturbances. Deceased patients had significantly higher levels of cfDNA, which was identified as the best predictor of prognosis in ESRD patients.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Gastroenterology & Hepatology
Sunil Taneja, Ajay Duseja, Manu Mehta, Arka De, Nipun Verma, Madhumita Premkumar, Radha K. Dhiman, Virendra Singh, Mini P. Singh, Radha K. Ratho, Raja Ramachandran, Vivek Kumar, Harbir S. Kohli
Summary: The study evaluated the safety and efficacy of Sofosbuvir plus Velpatasvir fixed-dose combination in treating CHC patients with ESRD on MHD. Results showed 100% of patients achieved ETR and 96% achieved SVR 12. All patients tolerated the combination without any serious adverse events.
LIVER INTERNATIONAL
(2021)
Article
Infectious Diseases
Trodia Zitha, Chien-Yu Chen, Hatim Mudawi, Waleed Hussein, Maowia Mukhtar, Mazin Shigidi, Mohamed Elamin Awad Yousif, Mohammed Ahmed Ali, Dieter Glebe, Anna Kramvis
Summary: This study genotyped and molecularly characterized HCV isolated from end-stage renal disease haemodialysis patients in Sudan. The results showed a high prevalence of HCV infection in this population, with evidence of nosocomial transmission. The findings are important for locating potential transmission chains and guiding individualized treatment.
BMC INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Annelieke Driessen, Erica Borgstrom, Simon Cohn
Summary: In recent years, policies have encouraged patients to choose their place of death, with a focus on dying at home. However, there is a tendency to simplify the concept of preferred place of death as a static geographical location, overlooking the continuous efforts of palliative care teams to create suitable environments for the dying process.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Andrology
Bulent Kaya, Mutlu Deger, Saime Paydas, Nebil Akdogan, Eda Altun, Erkan Kayar, Sevinc Puren Yucel, Mustafa Balal
Summary: Erectile dysfunction is more common in hemodialysis patients than in kidney transplantation recipients, with kidney transplantation shown to decrease the risk of ED.
Article
Urology & Nephrology
Shamira Shahar, Durga A. Arimuthu, Sadanah Aqashiah Mazlan
Summary: Carbapenem-induced neurotoxicity, especially with ertapenem, can lead to serious central nervous system toxicity in patients with chronic kidney disease. Proper dosing adjustment and clinical studies are needed to ensure antibiotic safety in these patients.
Article
Biochemistry & Molecular Biology
Ziad M. El-Zaatari, Luan D. Truong
Summary: Renal cell carcinoma (RCC) occurring in the setting of end-stage renal disease (ESRD) shows unique clinicopathological characteristics, with acquired cystic kidney disease-associated renal cell carcinoma (ACKD-RCC) and clear-cell papillary renal cell carcinoma (ccpRCC) being the most frequent types. Other types of RCC also occur in ESRD, albeit with different frequencies from the non-ESRD general population. While the histological features of RCC do not vary in the setting of ESRD vs. non-ESRD, other findings, such as multifocality and multiple tumor types, are more frequent in ESRD. Studies have generated novel and important knowledge of the etiology, epidemiology, diagnosis, treatment, immunophenotype, and molecular characteristics of ESRD-associated RCC.
Article
Urology & Nephrology
Timothy Moreels, Dominique van de Velde, Stephanie Van Duyse, Karsten Vanden Wyngaert, Tamara Leune, Wim Van Biesen, Patricia De Vriendt
Summary: This study aimed to explore the impact of in-centre haemodialysis on daily activities for older adults and identify potential areas for support. It found that older adults experienced a decline in daily activities since starting dialysis, particularly affecting their most meaningful activities. Early and continued support of these meaningful activities may be beneficial in improving their physical activity levels and coping abilities.
CLINICAL KIDNEY JOURNAL
(2023)
Article
Health Care Sciences & Services
Lena Axelsson, Anette Alvariza, Jenny Lindberg, Joakim Ohlen, Cecilia Hakanson, Helene Reimertz, Carl-Johan Furst, Kristofer Arestedt
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2018)
Article
Nursing
Lena Axelsson, Birgitta Klang, Carina Lundh Hagelin, Stefan H. Jacobson, Sissel Andreassen Gleissman
JOURNAL OF CLINICAL NURSING
(2015)
Article
Ethics
Lena Axelsson, Eva Benzein, Jenny Lindberg, Carina Persson
Article
Health Care Sciences & Services
Lena Axelsson, Eva Benzein, Jenny Lindberg, Carina Persson
BMC PALLIATIVE CARE
(2019)
Article
Health Care Sciences & Services
Lena Axelsson, Anette Alvariza, Nina Carlsson, S. Robin Cohen, Richard Sawatzky, Kristofer Arestedt
BMC PALLIATIVE CARE
(2020)
Article
Psychology, Multidisciplinary
Nina Carlsson, Anette Alvariza, Anders Bremer, Lena Axelsson, Kristofer Arestedt
Summary: This study describes symptoms of prolonged grief and self-reported health among bereaved family members of those who died from sudden cardiac arrest, with a focus on comparing spouses and non-spouses. The results show that spouses are more likely to experience prolonged grief and self-reported health problems compared to non-spouses.
OMEGA-JOURNAL OF DEATH AND DYING
(2023)
Article
Nursing
Anna Sandgren, Lena Axelsson, Tove Bylund-Grenklo, Eva Benzein
Summary: Family members' expressions of dignity in palliative care are multifaceted and complex, involving living as a respected human being, maintaining identity, feeling connected to others, and adapting to new situations. Two contextual factors, the two-headed paradox and reciprocal impact, influence family members' dignity in palliative care.
SCANDINAVIAN JOURNAL OF CARING SCIENCES
(2021)
Article
Health Care Sciences & Services
Lena Axelsson, Anette Alvariza, Maja Holm, Kristofer Arestedt
PALLIATIVE MEDICINE REPORTS
(2020)
Article
Nursing
Lena Axelsson, Birgitta Klang, Carina Lundh Hagelin, Stefan H. Jacobson, Sissel Andreassen Gleissman
SCANDINAVIAN JOURNAL OF CARING SCIENCES
(2015)
Article
Nursing
Lena Axelsson, Ingrid Randers, Stefan H. Jacobson, Birgitta Klang
SCANDINAVIAN JOURNAL OF CARING SCIENCES
(2012)
Article
Nursing
Lena Axelsson, Catrin Bjorvell, Anne-Cathrine Mattiasson, Ingrid Randers
JOURNAL OF CLINICAL NURSING
(2006)