Review
Clinical Neurology
Cillian McNamara, Kshitij Mankad, Stefanie Thust, Luke Dixon, Clara Limback-Stanic, Felice D'Arco, Thomas S. Jacques, Ulrike Lobel
Summary: The fifth edition of the WHO Classification of Tumours of the Central Nervous System introduces fundamental changes to brain tumor classification, especially in pediatric populations, by incorporating new tumor families and types. It emphasizes organizing tumors by molecular type to better reflect biology and facilitate treatment planning.
Review
Oncology
Francesco Sciancalepore, Francesco Fabozzi, Giulia Albino, Giada Del Baldo, Valentina Di Ruscio, Beatrice Laus, Danilo Menegatti, Roberto Premuselli, Domitilla Elena Secco, Alberto Eugenio Tozzi, Eleonora Lacorte, Nicola Vanacore, Andrea Carai, Angela Mastronuzzi
Summary: This systematic review aims to characterize cognitive deficits in survivors of paediatric Central Nervous System tumours and analyze their frequency. The most common cognitive impairment in this population is attention impairments, occurring in 52.3% of individuals. Other cognitive functions, such as executive functions, language, visuospatial skills, and memory, are also frequently impaired, affecting approximately 40% of survivors. Longitudinal studies show a decline in intellectual functioning over time. Future research should focus on implementing cognitive interventions and less neurotoxic tumor therapies to improve the neurocognitive functioning and quality of life of this population.
FRONTIERS IN ONCOLOGY
(2023)
Article
Clinical Neurology
Thomas Williams, Mohammad Naushahi, Anne Bernard, Robert Campbell
Summary: This study examined the epidemiology of childhood central nervous system tumors at Queensland Children's Hospital, providing insight into the incidence and presenting features in an Australian population. The study demonstrated a shorter symptom interval compared to previous literature, with the most frequent tumors located in the posterior fossa.
JOURNAL OF CLINICAL NEUROSCIENCE
(2021)
Article
Clinical Neurology
Elizabeth Schepke, Maja Lofgren, Torsten Pietsch, Thomas Olsson Bontell, Teresia Kling, Anna Wenger, Sandra Ferreyra Vega, Anna Danielsson, Sandor Dosa, Stefan Holm, Anders Oberg, Per Nyman, Marie Eliasson-Hofvander, Per-Erik Sandstrom, Stefan M. Pfister, Birgitta Lannering, Magnus Sabel, Helena Caren
Summary: DNA methylation analysis is a reliable method for the precise diagnosis of paediatric brain tumours, providing important molecular information for treatment decisions.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
(2022)
Article
Oncology
Kimberly D. Miller, Quinn T. Ostrom, Carol Kruchko, Nirav Patil, Tarik Tihan, Gino Cioffi, Hannah E. Fuchs, Kristin A. Waite, Ahmedin Jemal, Rebecca L. Siegel, Jill S. Barnholtz-Sloan
Summary: Brain and other CNS tumors are highly fatal cancers in the United States, with different incidence rates and survival rates among different races and age groups. Survival disparities, especially in childhood tumors, highlight the importance of providing more resources to advance research and understand the reasons behind differences in brain tumor occurrence, especially among rarer subtypes and understudied populations.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Public, Environmental & Occupational Health
Lindsay A. Williams, Aubrey K. Hubbard, Michael E. Scheurer, Logan G. Spector, Jenny N. Poynter
Summary: The study found that astrocytic tumours had the highest incidence rates globally among childhood central nervous system (CNS) tumours. There was a male excess in incidence for all cancers, with medulloblastoma having a consistently elevated male-to-female incidence rate ratio. Incidence trends varied regionally, and countries moving from lower to higher Human Development Index (HDI) did not drive observed trends in incidence.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Clinical Neurology
Pouya Jamshidi, Daniel J. J. Brat
Summary: The recently published WHO Classification of Tumours, Central Nervous System Tumours, Fifth Edition introduces significant clinical changes based on improved understanding of the molecular basis of brain tumor types. These changes provide neurologists with opportunities for individualized treatment options and the discovery of novel therapeutics.
CURRENT OPINION IN NEUROLOGY
(2022)
Article
Oncology
Sierra Cheng, John R. McLaughlin, M. Catherine Brown, Hamad Al-Sawaihey, James Rutka, Eric Bouffet, Cynthia Hawkins, A. Elizabeth Cairney, Adrianna Ranger, Adam J. Fleming, Donna Johnston, Mark Greenberg, David Malkin, Rayjean J. Hung
Summary: This study did not find a significant association between childhood brain tumors and previous history of head trauma, severity of head trauma, number of head injuries, or head/neck X-rays/CT examinations. Head trauma within the first year of life was significantly associated with brain tumors, but the association weakened when adjusted for X-rays or CT during the same time period.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Oncology
Wuqing Huang, Kristina Sundquist, Jan Sundquist, Jianguang Ji
Summary: Children of survivors with CNS tumor before the age of 20 did not show a significantly higher risk of overall somatic diseases compared to population controls. However, children with a paternal diagnosis of CNS tumor had a significantly increased risk of malignancies, infectious, and parasitic diseases.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Rachael Keating, Sarah Curry, Juliette Hussey
Summary: This study examined cardiorespiratory fitness and health-related quality of life in survivors of childhood central nervous system (CNS) tumors. The results showed that survivors had impaired cardiorespiratory fitness and lower quality of life. Higher levels of cardiorespiratory fitness were associated with higher levels of quality of life.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Oncology
David N. Louis, Arie Perry, Pieter Wesseling, Daniel J. Brat, Ian A. Cree, Dominique Figarella-Branger, Cynthia Hawkins, H. K. Ng, Stefan M. Pfister, Guido Reifenberger, Riccardo Soffietti, Andreas von Deimling, David W. Ellison
Summary: The fifth edition of the WHO Classification of Tumors of the Central Nervous System integrates molecular diagnostics into CNS tumor classification, introduces different approaches to tumor nomenclature and grading, and emphasizes the importance of integrated diagnoses and layered reports.
Article
Oncology
Danny R. Youlden, Chloe Henshaw, Nicholas G. Gottardo, Timothy Hassall, Joanne F. Aitken
Summary: The study found that the incidence rate of childhood CNS tumors increased by 29% between 1983 and 2016, with high-grade tumors on the rise. Among various diagnostic subtypes, astrocytoma and embryonal tumors were the most common. The overall 5-year survival rate was 72%, and although survival rates improved for some tumors over time, patients with high-grade astrocytoma still had poor outcomes.
JOURNAL OF NEURO-ONCOLOGY
(2021)
Review
Clinical Neurology
Craig Horbinski, Tamar Berger, Roger J. Packer, Patrick Y. Wen
Summary: The fifth edition of the WHO classification of CNS tumours, published in 2021, incorporates major changes in the classification system. This new edition includes more molecular alterations in tumor diagnosis and reorganizes the classification of gliomas and ependymomas. Several new tumor entities, especially pediatric tumors, are added to the 2021 classification. This significant revision will have a major impact on the diagnosis and treatment of CNS tumors.
NATURE REVIEWS NEUROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Faiza Basheer, Poshmaal Dhar, Rasika M. Samarasinghe
Summary: Paediatric brain cancer, the second most common childhood cancer, remains a significant challenge despite advancements in treatment. Further understanding of the molecular and heterogeneity of these brain tumors using animal models is crucial for addressing long-term therapy-associated side effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Wuqing Huang, Kristina Sundquist, Jan Sundquist, Jianguang Ji
Summary: Children of survivors with childhood or adolescent central nervous system (CNS) tumors did not have a significantly increased risk of overall psychiatric disorders, except for an elevated risk of mental retardation, particularly mild mental retardation. Boys of survivors had a higher risk of psychiatric disorders.
Article
Nursing
Dylan F. Flaws, Adrian Barnett, John Fraser, Jiville Latu, Mahesh Ramanan, Alexis Tabah, Vivienne Tippett, Oystein Tronstad, Sue Patterson
Summary: This study aims to describe recovery after ICU admission and identify predictors, correlates, and patient-reported outcomes of PICS. By collecting data from 300 patients, the study aims to support the development of screening, diagnostic, and outcome measures to enhance post-ICU recovery.
NURSING IN CRITICAL CARE
(2022)
Article
Anesthesiology
Christopher Thang, Prashanti Marella, Aashish Kumar, Mbakise Matebele, Mahesh Ramanan
Summary: Early use of albumin after cardiac surgery may be associated with reduced mortality, but it increases hospital and ICU lengths of stay.
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2022)
Article
Critical Care Medicine
Rachel L. Bailey, Mahesh Ramanan, Edward Litton, Nathalie Ssi Yan Kai, Fiona M. Coyer, Maite Garrouste-Orgeas, Alexis Tabah
Summary: This study evaluated the perceptions of ICU staff in Australia and New Zealand regarding visiting hours and family access. The results showed that open visiting was perceived as beneficial for relatives, but not as much for patients and staff. Staff identified risks to themselves, including increased workload, a risk of burnout, and a risk of occupational violence.
AUSTRALIAN CRITICAL CARE
(2022)
Article
Critical Care Medicine
Alexis Tabah, Mahesh Ramanan, Rachel L. Bailey, Shaila Chavan, Stuart Baker, Sue Huckson, David Pilcher, Edward Litton
Summary: In 2018, the majority of ANZ ICUs reported liberal visiting policies, with substantial facilities and family support.
AUSTRALIAN CRITICAL CARE
(2022)
Article
Medicine, General & Internal
Kevin B. Laupland, Kiran Shekar, Alexis Tabah, Pierre Clement, Felicity Edwards, Mahesh Ramanan
Summary: Patients with inflammatory bowel disease (IBD) suffer a major burden of critical illness, with an increased risk of mortality.
INTERNAL MEDICINE JOURNAL
(2023)
Article
Critical Care Medicine
Mark P. Plummer, Louise Rait, Mark E. Finnis, Craig J. French, Samantha Bates, James Douglas, Mansi Bhurani, Tessa Broadley, Tony Trapani, Adam M. Deane, Andrew A. Udy, Aidan J. C. Burrell
Summary: This study aimed to determine the prevalence and outcomes of diabetes in Australian ICU patients with severe COVID-19. The study found that diabetes is prevalent in ICU patients with COVID-19 in Australia, and patients with diabetes have longer hospital stays and higher mortality rates.
AUSTRALIAN CRITICAL CARE
(2023)
Article
Medicine, General & Internal
Alisa M. Higgins, Lindsay R. Berry, Elizabeth Lorenzi, Srinivas Murthy, Zoe McQuilten, Paul R. Mouncey, Farah Al-Beidh, Djillali Annane, Yaseen M. Arabi, Abi Beane, Wilma Van Bentum-Puijk, Zahra Bhimani, Marc J. M. Bonten, Charlotte A. Bradbury, Frank M. Brunkhorst, Aiden Burrell, Adrian Buzgau, Meredith Buxton, Walton N. Charles, Matthew Cove, Michelle A. Detry, Lise J. Estcourt, Elizabeth O. Fagbodun, Mark Fitzgerald, Timothy D. Girard, Ewan C. Goligher, Herman Goossens, Rashan Haniffa, Thomas Hills, Christopher M. Horvat, David T. Huang, Nao Ichihara, Francois Lamontagne, John C. Marshall, Daniel F. McAuley, Anna McGlothlin, Shay P. McGuinness, Bryan J. McVerry, Matthew D. Neal, Alistair D. Nichol, Rachael L. Parke, Jane C. Parker, Karen Parry-Billings, Sam E. C. Peters, Luis F. Reyes, Kathryn M. Rowan, Hiroki Saito, Marlene S. Santos, Christina T. Saunders, Ary Serpa-Neto, Christopher W. Seymour, Manu Shankar-Hari, Lucy M. Stronach, Alexis F. Turgeon, Anne M. Turner, Frank L. van de Veerdonk, Ryan Zarychanski, Cameron Green, Roger J. Lewis, Derek C. Angus, Colin J. McArthur, Scott Berry, Lennie P. G. Derde, Anthony C. Gordon, Steve A. Webb, Patrick R. Lawler
Summary: The longer-term effects of therapies for critically ill COVID-19 patients are unknown. In this study, 4869 patients were randomized to receive different interventions, and it was found that treatment with IL-6 receptor antagonists and antiplatelet agents significantly improved survival rates after 180 days. These findings suggest that most therapies have consistent effects over a 6-month period.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Emergency Medicine
Changle Song, Mark Dennis, Brian Burns, Sophie Dyson, Paul Forrest, Mahesh Ramanan, David Levinson, Emily Moylan
Summary: The study aimed to determine the best ECPR delivery strategy for optimal patient access, examine the time-sensitivity of ECPR in predicting survival, and model potential survival benefits from different ECPR delivery strategies. The results showed that the rendezvous and pre-hospital ECPR models significantly increased the catchment area of eligible OHCA patients.
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
(2022)
Article
Critical Care Medicine
Akram Zaaqoq, Matthew Griffee, Thu-Lan Kelly, Jonathon Fanning, Silver Heinsar, Jacky Suen, Silvia Mariani, Gianluigi Li Bassi, Jeffrey Jacobs, Nicole White, John Fraser, Roberto Lorusso, Giles Peek, Sung-Min Cho
Summary: This study aims to characterize the prevalence and risk factors of stroke secondary to COVID-19 in patients on venovenous ECMO. The results showed that obesity and pre-ECMO vasopressor use were associated with an increased risk of stroke. In addition, stroke patients had a more significant relative decrease in Paco(2) and relative increase in Pao(2) within 48 hours after ECMO initiation compared to non-stroke patients, and they also had a higher in-hospital mortality rate.
CRITICAL CARE MEDICINE
(2023)
Article
Emergency Medicine
Antony George Attokaran, Mahesh Ramanan, Lisa Hunt, Kavita Chandra, Rajbir Sandha, Stacey Watts, Balasubramanian Venkatesh
Summary: This study aimed to test whether fluid resuscitation with plasmalyte-148 (PL) compared to 0.9% sodium chloride (SC) in the emergency department (ED) would result in a lower proportion of diabetic ketoacidosis (DKA) patients requiring intensive care unit (ICU) admission. The results showed that patients treated with PL and SC had similar rates of ICU admission.
EMERGENCY MEDICINE AUSTRALASIA
(2023)
Article
Critical Care Medicine
Alexis Tabah, Niccolo Buetti, Quentin Staiquly, Stephane Ruckly, Murat Akova, Abdullah Tarik Aslan, Marc Leone, Andrew Conway Morris, Matteo Bassetti, Kostoula Arvaniti, Jeffrey Lipman, Ricard Ferrer, Haibo Qiu, Jose-Artur Paiva, Pedro Povoa, Liesbet De Bus, Jan De Waele, Farid Zand, Mohan Gurjar, Adel Alsisi, Khalid Abidi, Hendrik Bracht, Yoshiro Hayashi, Kyeongman Jeon, Muhammed Elhadi, Francois Barbier, Jean-Francois Timsit
Summary: This study investigated hospital-acquired bloodstream infections (HA-BSI) in 2600 adult patients from 333 ICUs in 52 countries. HA-BSI were frequently caused by Gram-negative, carbapenem-resistant, and difficult-to-treat pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy, resulting in high mortality rates.
INTENSIVE CARE MEDICINE
(2023)
Article
Medicine, General & Internal
Patrick R. Lawler, Lennie P. G. Derde, Frank L. van de Veerdonk, Bryan J. McVerry, David T. Huang, Lindsay R. Berry, Elizabeth Lorenzi, Roland van Kimmenade, Frank Gommans, Muthiah Vaduganathan, David E. Leaf, Rebecca M. Baron, Edy Y. Kim, Claudia Frankfurter, Slava Epelman, Yvonne Kwan, Richard Grieve, Stephen O'Neill, Zia Sadique, Michael Puskarich, John C. Marshall, Alisa M. Higgins, Paul R. Mouncey, Kathryn M. Rowan, Farah Al-Beidh, Djillali Annane, Yaseen M. Arabi, Carly Au, Abi Beane, Wilma van Bentum-Puijk, Marc J. M. Bonten, Charlotte A. Bradbury, Frank M. Brunkhorst, Aidan Burrell, Adrian Buzgau, Meredith Buxton, Maurizio Cecconi, Allen C. Cheng, Matthew Cove, Michelle A. Detry, Lise J. Estcourt, Justin Ezekowitz, Mark Fitzgerald, David Gattas, Lucas C. Godoy, Herman Goossens, Rashan Haniffa, David A. Harrison, Thomas Hills, Christopher M. Horvat, Nao Ichihara, Francois Lamontagne, Kelsey M. Linstrum, Daniel F. McAuley, Anna McGlothlin, Shay P. McGuinness, Zoe McQuilten, Srinivas Murthy, Alistair D. Nichol, David R. J. Owen, Rachael L. Parke, Jane C. Parker, Katrina M. Pollock, Luis Felipe Reyes, Hiroki Saito, Marlene S. Santos, Christina T. Saunders, Christopher W. Seymour, Manu Shankar-Hari, Vanessa Singh, Alexis F. Turgeon, Anne M. Turner, Ryan Zarychanski, Cameron Green, Roger J. Lewis, Derek C. Angus, Scott Berry, Anthony C. Gordon, Colin J. McArthur, Steve A. Webb
Summary: In patients with COVID-19, overactivation of the renin-angiotensin system (RAS) may have negative clinical outcomes. This study aimed to determine if initiating angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) could improve outcomes in hospitalized COVID-19 patients. The results showed that in critically ill patients, the use of ACE inhibitors or ARBs did not improve, and likely worsened, clinical outcomes.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Critical Care Medicine
Prashanti Marella, Kevin B. Laupland, Kiran Shekar, Alexis Tabah, Felicity Edwards, Mahesh Ramanan
Summary: Patient-centered outcomes such as institution-free days (IFD) are important in critical care trials. The study found that different definitions of IFD lead to different results, depending on how death and post-hospital deaths are handled. The study also identified significant associations between IFD and factors such as age, illness severity, comorbidities index, elective status, surgical/medical admission, and treatment limitations.
JOURNAL OF CRITICAL CARE
(2023)
Article
Nursing
Frances Lin, Alison Craswell, Lauren Murray, Jane Brailsford, Katrina Cook, Shivaprasad Anagi, Rachel Muir, Peter Garrett, Raju Pusapati, Joan Carlini, Mahesh Ramanan
Summary: This study aims to determine key priorities for critical care nursing research in three Australian regional public hospitals, representing the shared priorities of healthcare professionals and patient representatives. The research identified three main themes: patient flow through intensive care, patient care through intensive care journey, and intensive care patient recovery. These priorities will guide future nursing research in critical care over the next 3-5 years.
INTENSIVE AND CRITICAL CARE NURSING
(2023)
Correction
Critical Care Medicine
Bairbre A. McNicholas, Emanuele Rezoagli, Andrew J. Simpkin, Sankalp Khanna, Jacky Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. Fraser, John Laffey, Cccc Consortium
Review
Clinical Neurology
Oday Atallah, Amr Badary, Yasser F. Almealawy, Vivek Sanker, Wireko Andrew Awuah, Toufik Abdul-Rahman, Sura N. Alrubaye, Bipin Chaurasia
Summary: This study investigates unexpected deaths resulting from primary brain tumors and analyzes the contributing variables. The findings reveal that unexpected deaths are a complex phenomenon, with headache being the most common initial symptom and meningiomas and astrocytomas being the most common lesions.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Alexandra E. Quimby, Mandy K. Salmon, Christopher H. Zhao, John Y. K. Lee, Douglas C. Bigelow, Michael J. Ruckenstein, Jason A. Brant
Summary: The study found that socioeconomic factors including race, health insurance, and income have an impact on the quality of life at the time of vestibular schwannoma diagnosis. Black/African American and uninsured/self-pay patients had lower quality of life, while patients with higher income had higher quality of life.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Review
Clinical Neurology
Arosha S. Dissanayake, Kwok M. Ho, Timothy J. Phillips, Stephen Honeybul, Graeme J. Hankey
Summary: This study systematically reviews models that aim to provide patient-specific predictions of pre-treatment rebleeding risk in patients with aneurysmal subarachnoid hemorrhage. The reported discriminative performance of the models varied, and no model showed consistently low bias risk and clinical applicability in all domains. Only one model was formulated using a patient cohort that underwent contemporary, evidence-based aneurysm treatment practices, but this model lacked calibration or clinical utility.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Colin Kok Ann Teo, Yilong Zheng, Jeremy Bingyuan Lin, Hock Luen Teoh, Bernard Poon Lap Chan, Vijay Kumar Sharma, Kejia Teo, Vincent Diong Weng Nga, Tseng Tsai Yeo
Summary: This study retrospectively reviewed the clinical characteristics and outcomes after surgical revascularization for adult Moyamoya disease (MMD) in a Southeast Asian cohort. The incidence of postoperative transient ischemic attack (TIA)/stroke was 25.9%, with most cases occurring within 7 days postoperatively. Risk factors for 30-day postoperative TIA/stroke included a higher number of preoperative TIAs/strokes and indirect revascularization.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Cheng-Chi Lee, Abel Po-Hao Huang, Ching-Chang Chen, Zhuo-Hao Liu, Mun-Chun Yeap, Ko-Ting Chen, Peng-Wei Hsu, Kuo-Chen Wei, Chun-Ting Chen, Yu-Chi Wang, Ting-Wei Chang, Chi-Cheng Chuang
Summary: Using a novel portable neuroendoscopic system for minimally invasive evacuation of intracerebral hemorrhage (ICH) has shown positive outcomes in reducing hematoma volume and improving neurological function without any death or rebleeding incidents.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Michael M. Haglund, Bruce M. McCormack, Daniel M. Williams, Alexander C. Lemons, Erik M. Summerside
Summary: This study evaluated the long-term radiographic outcomes of patients receiving tissue-sparing posterior cervical fusion (PCF) for the treatment of pseudarthrosis. The results showed that patients achieved rates of arthrodesis similar to open PCF, with fewer postoperative complications and long-term soft tissue pain.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Dong-Dong Meng, Zhe Ruan, Yong-Lan Tang, Zhao-Hua Ji, Yue Su, Tuo Xu, Bo-Zhou Cui, Da-Lin Ren, Ting Chang, Qian Yang
Summary: Depression symptom level, MG severity classification and family's monthly per capita income are independent factors related to the caregivers' disease family burden for MG patients. The daily activity burden of the family and the economic burden of the family were the heaviest among the six dimensions of the caregivers' family disease burdens.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Tugba Ozudogru Celik, Umit Gorgulu, Safiye Gul Kenar, Nadide Koca, Elif Yalcin, Ipek Koymen, Evren Yasar
Summary: This study investigated the forward head posture (FHP), thoracic kyphosis, and their relationship in individuals with migraine compared to healthy controls. The results showed that patients with migraine had a greater FHP and thoracic kyphosis. This suggests that a 3-dimensional objective measurement could be a reliable tool for evaluating posture analysis in clinical practice.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Jason A. Chen, Ari D. Kappel, Erickson F. Torio, David I. Bass, Abdullah Feroze, Nirav J. Patel
Summary: This report presents a case of a 63-year-old woman with a ruptured giant ICA terminus aneurysm, who underwent coil embolization followed by parent vessel sacrifice and high-flow bypass.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Sandeep Kandregula, Sneha Sai Mannam, Shahbaz Saad, Saarang Patel, Visish M. Srinivasan
Summary: A 39-year-old female with a history of smoking and a family predisposition to unruptured aneurysms presented with clinical symptoms of intermittent right-sided headaches, flashes of light, and pulsatile tinnitus. Diagnostic evaluations identified a right occipital arteriovenous malformation (AVM). Treatment involved partial embolization of primary arterial feeders followed by surgical resection, resulting in a successful outcome.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Ari D. Kappel, Jason A. Chen, Joshua I. Chalif, David I. Bass, Erickson F. Torio, Abdullah H. Feroze, Nirav J. Patel
Summary: A 48-year-old male with progressive congestive myelopathy underwent surgical clipping to treat a craniocervical DAVF. Intraoperatively, ICG was used to confirm the solitary inflow.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Aryeh Zolin, Cenai Zhang, Hwai Ooi, Harini Sarva, Hooman Kamel, Neal S. Parikh
Summary: In people with Parkinson's disease, comorbid liver fibrosis is associated with more rapid cognitive decline across multiple domains.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)