Editorial Material
Obstetrics & Gynecology
Dominique de Ziegler, Petra de Sutter
Summary: Gender dysphoria affects approximately 0.5% of the population worldwide, with transgender men having access to gender affirming measures such as hormone therapy and surgical procedures.
FERTILITY AND STERILITY
(2021)
Review
Pharmacology & Pharmacy
Cosimo Andrea Stamerra, Paolo Di Giosia, Claudio Ferri, Paolo Giorgini, Zeljko Reiner, Thomas P. Johnston, Amirhossein Sahebkar
Summary: Statins may slightly impair adrenal and/or gonadal steroid hormone production, but do not cause clinically-relevant harmful effects on erectile function and spermatogenesis in men. They have beneficial effects in the treatment of polycystic ovary syndrome in women. Additional research is needed to provide specific clinical recommendations on this topic.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Review
Immunology
Linlin Xu, Yuan Yuan, Zhaodi Che, Xiaozhi Tan, Bin Wu, Cunchuan Wang, Chengfang Xu, Jia Xiao
Summary: Sex hormones and sex-related hormones play important roles in liver diseases, depending on biological sex, disease stage, and other factors. Lifestyle factors also affect the mechanisms of these hormones in liver diseases. Hormone therapy may be a strategy for treating metabolic liver disease, cirrhosis, and liver cancer, but adverse hormone-induced liver injury needs to be carefully studied and monitored.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Orthopedics
Duncan C. Ramsey, Michelle M. Lawson, Ariana Stuart, Emelia Sodders, Zachary M. Working
Summary: Transgender individuals have a gender identity incongruent with their biological sex assigned at birth, with a large and growing population in the U.S. Gender-affirming hormone therapy has physiological effects on patients' health, affecting aspects such as bone health, fracture risk, and perioperative risks. Language and accurate pronoun usage towards transgender patients can have significant impacts on their experience and outcomes, highlighting the need for further research in orthopaedic care for this population.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Physiology
Jonathon W. Senefeld, Sandra K. Hunter, Doriane Coleman, Michael J. Joyner
Summary: There is controversy about the eligibility regulations for transgender athletes in sports competition. This case study examines the swimming performances of an elite transgender woman before and after hormone therapy, showing that her performance decline is smaller than the observed sex-related differences in top world record performances. Despite slower times, the transgender woman swimmer outperformed rank-matched swimmers in the women's NCAA category. This analysis provides insights for regulators in creating inclusive participation guidelines.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Nuozhou Liu, Ying Feng, Xinyao Luo, Xue Ma, Fang Ma
Summary: This study reveals an association between a proinflammatory diet and decreased levels of SHBG in women, particularly in premenopausal women.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Oncology
Mikael Agopiantz, Melanie Carnot, Constance Denis, Elena Martin, Guillaume Gauchotte
Summary: This study reports the expression of progesterone, estrogen, androgen, and somatostatin receptors in meningiomas, based on immunohistochemistry. The findings provide insights into the relationship between receptor expression and various factors such as age, sex, hormonal context, localization, histological subtype, grade, and recurrence.
Article
Radiology, Nuclear Medicine & Medical Imaging
Justin T. Stowell, Priyanka Jha, Jorys Martinez-Jorge, Erik H. Middlebrooks, Daniel F. Broderick, Alok A. Bhatt
Summary: Transgender individuals may suffer from gender dysphoria and undergo reconstructive surgeries to align their appearance with their gender identity. Maxillofacial CT plays a crucial role in preoperative evaluation.
Review
Oncology
Florent Morfoisse, Audrey Zamora, Emmanuelle Marchaud, Manon Nougue, Leila H. Diallo, Florian David, Emilie Roussel, Eric Lacazette, Anne-Catherine Prats, Florence Tatin, Barbara Garmy-Susini
Summary: Lymphedema is a lifelong disease affecting the lymphatic system, characterized by swelling of the limbs and accumulation of fluid. While it predominantly affects women, particularly those who undergo hormone therapy after breast cancer surgery, the role of female hormones in secondary lymphedema is still poorly understood.
Review
Medicine, Research & Experimental
Joshua D. Safer
Summary: Transgender health research is often limited and subsumed in larger LGBTQ studies. The medical approach to transgender health is changing, but the number of knowledgeable healthcare providers remains modest. More research and dedicated funding are needed to address the knowledge gap in the field.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Review
Endocrinology & Metabolism
Mabel Yau, Robert Rapaport
Summary: The evaluation of children with short stature involves long-term monitoring to establish growth patterns and rule out chronic medical conditions. Growth hormone stimulation testing is essential for diagnosing growth hormone deficiency, although its results are influenced by various factors.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cell Biology
Huan Li, Weibo Jiang, Shui Liu, Manshi Yang, Siyuan Chen, Yihan Pan, Mengying Cui
Summary: Sex differences in cancer incidence and survival are constant and pronounced globally, and researchers have started focusing on the molecular mechanisms behind these differences. Besides sex hormones, genetic and molecular pathways also play a role in cancer development and treatment response. Clarifying the essential mechanisms of gender differences will guide the clinical treatment of both sexes in cancer therapy.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Article
Environmental Sciences
Weilong Xing, Wen Gu, Mengyuan Liang, Zhen Wang, Deling Fan, Bing Zhang, Lei Wang
Summary: This study investigates the association between aldehyde exposure and sex hormone levels. The results show that certain aldehydes are negatively associated with sex hormones, with specific effects observed in different genders and age groups. Further research is needed to confirm the causal relationship and explore the underlying mechanisms.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Medicine, General & Internal
Ji-Won Kim, Hyoun-Ah Kim, Chang-Hee Suh, Ju-Yang Jung
Summary: SLE affects women more frequently than men, and male patients exhibit different clinical features than female patients. Sex hormones play a crucial role in the pathogenesis, clinical features, and management of SLE. Understanding the occurrence and exacerbation of disease caused by sex hormones is necessary to improve the management of SLE.
FRONTIERS IN MEDICINE
(2022)
Review
Endocrinology & Metabolism
C. Szoeke, S. J. Downie, A. F. Parker, S. Phillips
Summary: This paper discusses the role of sex hormones in the intersection of vascular disease and dementia, emphasizing interactive risk factors and the role of inflammation in the evolution of the disease, as well as the impact of estrogen-based hormone therapy on cognition over the past 45 years.
FRONTIERS IN NEUROENDOCRINOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Samuel L. Rice, Amy R. Deipolyi, Ernesto Santos Martin
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Article
Gastroenterology & Hepatology
Rocio Perez-Johnston, Amy R. Deipolyi, Anne M. Covey
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
(2018)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Amy R. Deipolyi, Jacqueline F. Bromberg, Joseph P. Erinjeri, Stephen B. Solomon, Lynn A. Brody, Christopher C. Riedl
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Review
Medicine, General & Internal
Ryan W. England, Eliza B. Geer, Amy R. Deipolyi
JOURNAL OF CLINICAL MEDICINE
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Amy R. Deipolyi, Christopher C. Riedl, Jacqueline Bromberg, Sarat Chandarlapaty, Christopher A. Klebanoff, Constantinos T. Sofocleous, Hooma. N. Yarmohammadi, Lynn A. Brody, F. Edward Boas, Etay Ziv
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Majid Maybody, Nadim Muallem, Karen T. Brown, Chava S. Moskowitz, Meier Hsu, Christina L. Zenobi, Marwah Jihad, George Getraidman, Constantinos T. Sofocleous, Joseph P. Erinjeri, Anne M. Covey, Lynn A. Brody, Hooman Yarmohammadi, Amy R. Deipolyi, Yolanda Bryce, William Alago, Robert H. Siegelbaum, Jeremy C. Durack, Adrianj Gonzalez-Aguirre, Etay Ziv, F. Edward Boas, Stephen B. Solomon
Review
Chemistry, Multidisciplinary
Jingjie Hu, Hassan Albadawi, Brian W. Chong, Amy R. Deipolyi, Rahul A. Sheth, Ali Khademhosseini, Rahmi Oklu
ADVANCED MATERIALS
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrew B. Rosenkrantz, Meridith J. Englander, Amy R. Deipolyi, Laura Findeiss, Richard Duszak
AMERICAN JOURNAL OF ROENTGENOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Amy R. Deipolyi, Ryan W. England, Fourat Ridouani, Christopher C. Riedl, Henry S. Kunin, F. Edward Boas, Hooman Yarmohammadi, Constantinos T. Sofocleous
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Amy R. Deipolyi, Anton S. Becker, Anne M. Covey, Susan C. Chimonas, Andrew B. Rosenkrantz, Howard P. Forman, William A. Copen
AMERICAN JOURNAL OF ROENTGENOLOGY
(2020)
Letter
Cardiac & Cardiovascular Systems
Amy R. Deipolyi, Ryan W. England, Fourat Ridouani, Christopher C. Riedl, Henry S. Kunin, F. Edward Boas, Hooman Yarmohammadi, Constantinos T. Sofocleous
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fourat Ridouani, Stephen B. Solomon, Yolanda Bryce, Jacqueline F. Bromberg, Constantinos T. Sofocleous, Amy R. Deipolyi
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ariel N. Liberchuk, Amy R. Deipolyi
SEMINARS IN INTERVENTIONAL RADIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fourat Ridouani, Mohamed M. Soliman, Ryan W. England, Meier Hsu, Chaya S. Moskowitz, Raphael Doustaly, Constantinos T. Sofocleous, F. Edward Boas, Hooman Yarmohammadi, Amy R. Deipolyi
Summary: This study aimed to investigate the relationship between tumoral and nontumoral radiation doses and response/toxicity in breast cancer patients with liver metastasis undergoing TARE. The results indicated that higher tumoral radiation doses were associated with objective response and longer survival, while pre-existing liver dysfunction was linked to increased hepatotoxicity and reduced survival.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Amy R. Deipolyi, Christopher D. Czaplicki, Rahmi Oklu
CARDIOVASCULAR DIAGNOSIS AND THERAPY
(2018)
Review
Clinical Neurology
Oday Atallah, Amr Badary, Yasser F. Almealawy, Vivek Sanker, Wireko Andrew Awuah, Toufik Abdul-Rahman, Sura N. Alrubaye, Bipin Chaurasia
Summary: This study investigates unexpected deaths resulting from primary brain tumors and analyzes the contributing variables. The findings reveal that unexpected deaths are a complex phenomenon, with headache being the most common initial symptom and meningiomas and astrocytomas being the most common lesions.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Alexandra E. Quimby, Mandy K. Salmon, Christopher H. Zhao, John Y. K. Lee, Douglas C. Bigelow, Michael J. Ruckenstein, Jason A. Brant
Summary: The study found that socioeconomic factors including race, health insurance, and income have an impact on the quality of life at the time of vestibular schwannoma diagnosis. Black/African American and uninsured/self-pay patients had lower quality of life, while patients with higher income had higher quality of life.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Review
Clinical Neurology
Arosha S. Dissanayake, Kwok M. Ho, Timothy J. Phillips, Stephen Honeybul, Graeme J. Hankey
Summary: This study systematically reviews models that aim to provide patient-specific predictions of pre-treatment rebleeding risk in patients with aneurysmal subarachnoid hemorrhage. The reported discriminative performance of the models varied, and no model showed consistently low bias risk and clinical applicability in all domains. Only one model was formulated using a patient cohort that underwent contemporary, evidence-based aneurysm treatment practices, but this model lacked calibration or clinical utility.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Colin Kok Ann Teo, Yilong Zheng, Jeremy Bingyuan Lin, Hock Luen Teoh, Bernard Poon Lap Chan, Vijay Kumar Sharma, Kejia Teo, Vincent Diong Weng Nga, Tseng Tsai Yeo
Summary: This study retrospectively reviewed the clinical characteristics and outcomes after surgical revascularization for adult Moyamoya disease (MMD) in a Southeast Asian cohort. The incidence of postoperative transient ischemic attack (TIA)/stroke was 25.9%, with most cases occurring within 7 days postoperatively. Risk factors for 30-day postoperative TIA/stroke included a higher number of preoperative TIAs/strokes and indirect revascularization.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Cheng-Chi Lee, Abel Po-Hao Huang, Ching-Chang Chen, Zhuo-Hao Liu, Mun-Chun Yeap, Ko-Ting Chen, Peng-Wei Hsu, Kuo-Chen Wei, Chun-Ting Chen, Yu-Chi Wang, Ting-Wei Chang, Chi-Cheng Chuang
Summary: Using a novel portable neuroendoscopic system for minimally invasive evacuation of intracerebral hemorrhage (ICH) has shown positive outcomes in reducing hematoma volume and improving neurological function without any death or rebleeding incidents.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Michael M. Haglund, Bruce M. McCormack, Daniel M. Williams, Alexander C. Lemons, Erik M. Summerside
Summary: This study evaluated the long-term radiographic outcomes of patients receiving tissue-sparing posterior cervical fusion (PCF) for the treatment of pseudarthrosis. The results showed that patients achieved rates of arthrodesis similar to open PCF, with fewer postoperative complications and long-term soft tissue pain.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Dong-Dong Meng, Zhe Ruan, Yong-Lan Tang, Zhao-Hua Ji, Yue Su, Tuo Xu, Bo-Zhou Cui, Da-Lin Ren, Ting Chang, Qian Yang
Summary: Depression symptom level, MG severity classification and family's monthly per capita income are independent factors related to the caregivers' disease family burden for MG patients. The daily activity burden of the family and the economic burden of the family were the heaviest among the six dimensions of the caregivers' family disease burdens.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Tugba Ozudogru Celik, Umit Gorgulu, Safiye Gul Kenar, Nadide Koca, Elif Yalcin, Ipek Koymen, Evren Yasar
Summary: This study investigated the forward head posture (FHP), thoracic kyphosis, and their relationship in individuals with migraine compared to healthy controls. The results showed that patients with migraine had a greater FHP and thoracic kyphosis. This suggests that a 3-dimensional objective measurement could be a reliable tool for evaluating posture analysis in clinical practice.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Jason A. Chen, Ari D. Kappel, Erickson F. Torio, David I. Bass, Abdullah Feroze, Nirav J. Patel
Summary: This report presents a case of a 63-year-old woman with a ruptured giant ICA terminus aneurysm, who underwent coil embolization followed by parent vessel sacrifice and high-flow bypass.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Sandeep Kandregula, Sneha Sai Mannam, Shahbaz Saad, Saarang Patel, Visish M. Srinivasan
Summary: A 39-year-old female with a history of smoking and a family predisposition to unruptured aneurysms presented with clinical symptoms of intermittent right-sided headaches, flashes of light, and pulsatile tinnitus. Diagnostic evaluations identified a right occipital arteriovenous malformation (AVM). Treatment involved partial embolization of primary arterial feeders followed by surgical resection, resulting in a successful outcome.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Ari D. Kappel, Jason A. Chen, Joshua I. Chalif, David I. Bass, Erickson F. Torio, Abdullah H. Feroze, Nirav J. Patel
Summary: A 48-year-old male with progressive congestive myelopathy underwent surgical clipping to treat a craniocervical DAVF. Intraoperatively, ICG was used to confirm the solitary inflow.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)
Article
Clinical Neurology
Aryeh Zolin, Cenai Zhang, Hwai Ooi, Harini Sarva, Hooman Kamel, Neal S. Parikh
Summary: In people with Parkinson's disease, comorbid liver fibrosis is associated with more rapid cognitive decline across multiple domains.
JOURNAL OF CLINICAL NEUROSCIENCE
(2024)