Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 52, Issue 5, Pages 1751-1753Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00469-14
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A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid ( CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.
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