4.7 Article

High Nasal Burden of Methicillin-Resistant Staphylococcus aureus Increases Risk of Invasive Disease

Journal

JOURNAL OF CLINICAL MICROBIOLOGY
Volume 52, Issue 1, Pages 312-314

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01606-13

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  1. Department of Medicine, University of California Irvine

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In a retrospective cohort study of 1,140 patients harboring methicillin-resistant Staphylococcus aureus, the nasal burden was low in 31%, category 1+ to 2+ in 54%, and category 3+ to 4+ in 15%. There was a significant trend in infection risk with increasing nasal burden (P = 0.007). In multivariate models, high nasal burden remained significantly associated with invasive infection.

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