Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 51, Issue 1, Pages 278-280Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.02120-12
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Funding
- National Center for Advancing Translational Sciences [8KL2TR000134-07]
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In a large prospective comparison, the illumigene test detected Clostridium difficile in 98% of toxin-positive and 58% of toxin-negative samples confirmed positive by other methods. The Xpert was uniformly sensitive. Most samples with discrepant results had C. difficile concentrations below the illumigene limit of detection. The significance of low-level C. difficile detection needs investigation.
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