Article
Pharmacology & Pharmacy
Sook Kwan Brown, Yeu-Yang Tseng, Ammar Aziz, Mariana Baz, Ian G. Barr
Summary: This study tested 3425 influenza B viruses collected from the Asia-Pacific region against four registered neuraminidase inhibitors (NAIs). It identified 45 influenza B viruses with reduced susceptibility to one or more NAIs, including some with newly identified neuraminidase mutations. The study highlights the potential impact of these mutations on the clinical effectiveness of NAIs in treating influenza B infections in humans.
ANTIVIRAL RESEARCH
(2022)
Article
Telecommunications
Zhefu Wu, Xinyu Xiao, Chao Lin, Shufeng Gong, Luping Fang
Summary: WiFi-based person identification has become possible due to the widespread adoption of WiFi devices. However, existing methods have limitations in terms of speed and scalability as they rely on gait characters and require several minutes of walking for training and testing. To overcome these challenges, a novel WiFi-based Device-Free Fast Identification (WiDFF-ID) approach is proposed. It utilizes RF-based biometrics to derive personal Channel State Information (CSI) fingerprints, enabling quick identification for more individuals. The proposed scheme achieves an average identification accuracy of 98% with 42 volunteers, demonstrating its potential for access authentication in scenarios involving larger groups of people.
IEEE TRANSACTIONS ON COGNITIVE COMMUNICATIONS AND NETWORKING
(2023)
Article
Virology
Daniela Loconsole, Francesca Centrone, Valerio Aprile, Anna Sallustio, Daniele Casulli, Marisa Accogli, Davide Sacco, Riccardo Zagaria, Maria Chironna
Summary: This study investigated an influenza outbreak that occurred in southern Italy in August 2022, and found that influenza viruses circulated out-of-season during the summer months, which may be linked to changing dynamics in the post-COVID-19 era and climate change. Year-round surveillance of respiratory viruses is necessary to monitor this phenomenon and provide effective prevention strategies.
Article
Virology
Alexandra Duev-Cohen, Batya Isaacson, Orit Berhani, Yoav Charpak-Amikam, Nehemya Friedman, Yaron Drori, Michal Mandelboim, Ofer Mandelboim
Summary: The study found that NKp46 can recognize influenza B viruses, but the interaction strength is weaker compared to influenza A, and NKp46 is not crucial for eliminating influenza B.
Review
Microbiology
Alvin X. Han, Simon P. J. de Jong, Colin A. Russell
Summary: This review summarizes the interplay between immunity evolution from previous infections or vaccination and the evolution of seasonal influenza viruses, including functional constraints, within-host evolutionary processes, and options for influenza virus control. It is found that seasonal influenza viruses continually evolve to escape host immunity, driven by viral constraints and host immune responses. However, it remains unclear how these advances can effectively reduce the impact of seasonal influenza on human health.
NATURE REVIEWS MICROBIOLOGY
(2023)
Article
Infectious Diseases
Saima Hasan, Richard J. Webby, Muhammad Iqbal, Hamad Bin Rashid, Mansur-ud-Din Ahmad, Jawad Nazir, Jennifer DeBeauchamp, Shakera Sadiq, Mamoona Chaudhry
Summary: This study described the proportions, temporal and spatial distribution, and demographic and clinical characteristics of influenza A virus positive patients in Lahore, Pakistan. It identified distinct trends of ILI, SARI, and IAV positive cases, which can be used to inform public health interventions. Sampling from both ILI and SARI patients in routine surveillance is recommended.
BMC INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Ye-Ling Liu, Tian-Ao Xie, Geng-Ling Lin, Wei Deng, Qin-Rong Lin, Zhi-Yong Pan, Shu-Jin Fan, Zhen-Xing Li, Shi Ouyang, Guo-Dong Zhu, Tian-Xing Ji, Li-Juan Wu, Yong Xia, Xu-Guang Guo
Summary: The study confirmed the accuracy of Xpert Xpress Flu/RSV in detecting influenza virus and RSV, and demonstrated its high sensitivity and specificity.
JAPANESE JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Microbiology
Eddie Chi-man Leung, Viola Chi-ying Chow, May Kin-ping Lee, Kevin Pui-san Tang, Daniel Kwok-cheung Li, Raymond Wai-man Lai
Summary: The study found that the Xpert 4-in-1 assay showed high concordance with the comparator assays for detecting and differentiating SARS-CoV-2, flu A, flu B, and RSV, with an almost perfect correlation between the assays.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Microbiology
Laura Sanchez-de Prada, Silvia Rojo-Rello, Marta Dominguez-Gil, Eduardo Tamayo-Gomez, Raul Ortiz de Lejarazu-Leonardo, Jose Maria Eiros, Ivan Sanz-Munoz
Summary: The study evaluated the cross-protection provided by the trivalent influenza vaccine and compared serological profiles based on age, sex, and vaccine type. It was found that heterotypic reactivity between the two influenza B lineages is common, but always lower than the homologous response. Age is a relevant factor for cross-reactivity between the lineages, while sex and vaccine type are not.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Infectious Diseases
Wei-juan Huang, Yan-hui Cheng, Min-ju Tan, Jia Liu, Xi-yan Li, Xiao-xu Zeng, Jing Tang, He-jiang Wei, Tao Chen, Lei Yang, Yi-ran Xie, Jia-ying Yang, Ning Xiao, Da-yan Wang
Summary: Influenza activity in mainland China recovered and intensified in 2021, resulting in the flu season in winter 2021-2022. Although the diversity of influenza (sub)types decreases, B/Victoria lineage viruses show increased genetic and antigenic diversity. The world needs to be prepared for the co-epidemic of influenza and SARS-CoV-2 globally.
INFECTIOUS DISEASES OF POVERTY
(2022)
Article
Multidisciplinary Sciences
Tomoko Arita, Yasushi Suzuki, Noriko Shimasaki, Hirotaka Kobayashi, Hideki Hasegawa, Takato Odagiri, Masato Tashiro, Eri Nobusawa
Summary: Manufactured influenza vaccines require a defined amount of hemagglutinin (HA) antigen, and vaccines with a high HA antigen yield (HAY) are preferred for rapid production. This study identified the viral properties associated with HAY and found that TPY, rather than the %-HA content, was correlated with HAY. Altering the sequences of the 3' noncoding region of HA vRNA or replacing the master virus improved HAY and TPY without changing the %-HA content. Further analyses revealed that increased virus growth and more viral particles contributed to the improved HAY. These findings are crucial for developing high-HAY vaccine viruses.
Article
Chemistry, Analytical
Muhabat Adeola Raji, Yumna Aloraij, Fatimah Alhamlan, Ghadeer Suaifan, Karina Weber, Dana Cialla-May, Juergen Popp, Mohammed Zourob
Summary: This study developed a novel, low-cost and easy-to-use colorimetric flu virus biosensor assay. The assay utilizes a sandwich format with antibodies immobilized on cotton swabs for rapid detection of flu A and B viruses.
Article
Chemistry, Medicinal
Goran Bajic, Stephen C. Harrison
Summary: The study describes cross-reactive human antibodies recognizing influenza B viruses that have undergone nearly 80 years of antigenic drift. The structures of the antibodies show strong similarities to their influenza A counterparts in engaging the receptor-binding site of the viral hemagglutinin, despite structural differences between influenza A and B. These antibodies readily cross-react with both influenza B Victoria and Yamagata lineages, and are all encoded by IGHV3-9/IGK1-33. Further research will provide insights into the prevalence of these antibodies in the human population.
ACS INFECTIOUS DISEASES
(2021)
Article
Immunology
Tiphany Chrun, Emmanuel A. Maze, Kelly J. Roper, Eleni Vatzia, Basudev Paudyal, Adam McNee, Veronica Martini, Tanuja Manjegowda, Graham Freimanis, Adrian Silesian, Noemi Polo, Becky Clark, Emily Besell, Georges Booth, Brigid Veronica Carr, Matthew Edmans, Alejandro Nunez, Surapong Koonpaew, Nanchaya Wanasen, Simon P. P. Graham, Elma Tchilian
Summary: Porcine respiratory disease is commonly caused by co-infections of swine influenza A (swIAV) and porcine reproductive and respiratory syndrome (PRRSV) viruses. However, the immune responses and pathogenesis of these co-infections have not been well studied. In this study, pigs were co-infected with swIAV H3N2 and PRRSV-2, and it was found that the clinical disease was not worsened and viral load was reduced in the co-infected animals. Additionally, the development of virus-specific adaptive immune responses was not impaired. These findings suggest that simultaneous swIAV H3N2/PRRSV-2 co-infection does not negatively affect host immune responses.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Immunology
Xuejie Liu, Tianyi Zhao, Liangliang Wang, Zhuolin Yang, Chuming Luo, Minchao Li, Huanle Luo, Caijun Sun, Huacheng Yan, Yuelong Shu
Summary: The study utilized a mosaic vaccine design strategy and genetic algorithms to optimize the influenza virus antigens and generate virus-like particles. Compared to a commercial quadrivalent inactivated influenza vaccine, the mosaic VLPs induced stronger cross-reactive antibody responses, robust T-cell responses, and provided better protection in a mouse model. These findings demonstrate the promising potential of mosaic vaccines for developing a broad influenza vaccine in the future.
Article
Geosciences, Multidisciplinary
Haihai Hou, Longyi Shao, Yue Tang, Zhen Li, Sheng Zhao, Minglei Yao, Xuetian Wang, Jiaqiang Zhang
Summary: This study focuses on characterizing the pore structure of coal reservoirs in northern China. By utilizing various techniques such as proximate analysis, coal petrology, and nuclear magnetic resonance, the study examines the coal samples from three coalbed methane exploration areas. The results show that coalification and igneous intrusion greatly influence the coal properties, including vitrinite content, pore connectivity, and methane adsorption capacity. The study also reveals the complex variation in pore size distribution and highlights the best target maturity level for CBM exploitation.
Article
Computer Science, Theory & Methods
Xu Jiang, Haochun Liang, Nan Guan, Yue Tang, Lei Qiao, Yi Wang
Summary: This study investigates the scheduling of real-time parallel tasks on virtual multiprocessors. Through comprehensive performance evaluation, the proposed approach consistently outperforms existing methods under a wide range of parameter settings.
IEEE TRANSACTIONS ON PARALLEL AND DISTRIBUTED SYSTEMS
(2023)
Article
Agriculture, Multidisciplinary
Zhiyu Liu, Songyi Lin, Wenwen Liu, Yoshimasa Nakamura, Yue Tang
Summary: In this study, fish skin gelatin (FSG) and luteolin (LUT) were used as composite emulsifiers, and benzyl isothiocyanate (BITC) was used as a model nutrient for delivery. The FSG-LUT emulsion showed higher stability and embedding rate compared to the FSG emulsion. It also demonstrated resistance to oral and gastric digestion, resulting in higher retention and bioaccessibility of BITC. Furthermore, the ex vivo study in rat intestine showed that the FSG-LUT emulsion facilitated controlled release and absorption of BITC in a specific position.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Ziyuan Xia, Shipeng Wang, Yao Chen, Min Gou, Zhaoyong Sun, Songtao Wang, Suyi Zhang, Yueqin Tang
Summary: This study investigated the microbial consortia and flavor metabolites in Chinese liquor fermentation using a new-type sealing pit and a traditional sealing pit. The results showed that the new-type sealing method resulted in higher concentrations of flavor metabolites and a more stable microbial community. These findings are important for optimizing the fermentation process.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Jianwen Ding, Yue Tang, Ronghui Chang, Yu Li, Limin Zhang, Feng Yan
Summary: In this paper, a novel ECG electrode structure is designed to collect ECG data and reference data simultaneously. Combined with the adaptive filter, it effectively suppresses the motion artifact in the ECG acquisition.
Article
Geosciences, Multidisciplinary
Pei-yuan Hu, Qing-guo Zhai, Peter A. Cawood, Roberto F. Weinberg, Guo-chun Zhao, Yue Tang, Yi-ming Liu
Summary: Paleogeographic reconstruction of Precambrian terranes reworked by Phanerozoic orogens, such as the Tibetan Plateau, reveals complex lithotectonic relations due to intracrustal reworking. Global and regional detrital zircon rare earth element (REE) databases show trends in LREE/HREE and Eu/Eu* that record the crustal evolution of the source and provide a new approach for paleogeographic reconstructions. By analyzing sedimentary and igneous rocks in the Lhasa terrane and detrital zircon samples from the northern margin of Gondwana, it is demonstrated that the Lhasa terrane had an African affinity in the Rodinia-Gondwana supercontinent cycles (ca. 1.4-0.4 Ga).
GEOPHYSICAL RESEARCH LETTERS
(2023)
Article
Engineering, Electrical & Electronic
Xuan Ding, Ying Xu, Tangyao Feng, Zili Yang, Guilun Chen, Li Ren, Jing Shi, Difan Zhou, Jingdong Li, Yuejin Tang
Summary: Superconducting power devices based on high-temperature superconducting wires have many advantages and their development has been accelerated by successful prototypes and testing on the power grid. However, the reliability of these devices under overcurrent has not been supported by research, which hinders their large-scale promotion. This article analyzes the critical current degradation and life distribution characteristics of YBCO tapes under overcurrent, and proposes prediction models for their remaining useful life based on data-driven methods.
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY
(2023)
Article
Business
Shu Guo, Xuting Sun, Hugo K. S. Lam
Summary: This article studies the information disclosure games over the environmental efforts in fashion supply chains and discusses how the application of blockchain technology influences these games.
IEEE TRANSACTIONS ON ENGINEERING MANAGEMENT
(2023)
Article
Geology
Wei Wang, Qing-Guo Zhai, Pei-Yuan Hu, Yue Tang, Zhi-Cai Zhu
Summary: The studied Early Cretaceous andesitic rocks in the Nyima area, north-central Tibet, were formed by partial melting of Bangong-Nujiang oceanic lithosphere with the addition of enriched sedimentary materials.
INTERNATIONAL GEOLOGY REVIEW
(2023)
Article
Oncology
Tianzhuo Wang, Huiying Guo, Lei Zhang, Miao Yu, Qianchen Li, Jing Zhang, Yan Tang, Hongquan Zhang, Jun Zhan
Summary: FRMD6, a member of the 4.1 ezrin-radixin-moesin domain-containing protein family, is overexpressed in lung cancer tissues and is associated with poor outcomes in patients with lung squamous cell carcinoma and lung adenocarcinoma. FRMD6 promotes cell migration, proliferation, and tumor formation in lung cancer by interacting with and enhancing the mTOR signaling pathway. Knocking out FRMD6 inhibits the activation of the mTOR signaling pathway in mouse models.
FRONTIERS OF MEDICINE
(2023)
Article
Food Science & Technology
Guang-yao Zhang, Cong Sun, Jing-ru Song, Wei-yi Jin, Yue Tang, Da-yong Zhou, Liang Song
Summary: Glycated WPI-stachyose conjugates were prepared and showed increased inhibition of α-amylase activity and delayed glucose dialysis. These conjugates also exhibited reduced digestion by pepsin and trypsin compared to unconjugated WPI, and a 70% lower hydrolysis rate of stachyose. These findings suggest the potential use of glycated conjugates as functional ingredients with sustained-release effect in the gastrointestinal tract.
Article
Agricultural Engineering
Jin-Ting He, Nan Yao, Zhao-Yong Sun, Feng Li, He-Qing Cai, Li-Feng Jin, Yue-Qin Tang
Summary: Tobacco processing waste can be used as feedstock for biogas production through anaerobic digestion. This study examined the thermophilic anaerobic digestion of flue-cured tobacco leaf waste and evaluated the effects of biochar on biogas production. The addition of biochar enhanced methane production by 1.12-1.20 fold at different organic loads. The presence of biochar shortened the lag period and increased the methane production rate. Specific bacterial and methanogenic genera played a crucial role in the digestion process. These findings provide valuable insights for the treatment of tobacco waste.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Engineering, Mechanical
Jun Ma, Chunyang Yin, Zhonghua Zhou, Shiyou Chen
Summary: Various design methods were adopted to reduce energy consumption and improve service stability and security of the cutterhead, including lightweight design, modal optimization, and life prediction. A multi-disciplinary design optimization methodology was used to determine the design parameters for each discipline, and a Kriging model was employed to approximate the relationship between mode frequency, fatigue life, and design parameters. A collaborative optimization approach was utilized to establish system-level and subsystem-level optimization models, and a genetic algorithm was used for iterative optimization to achieve overall improvement.
JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY
(2023)
Article
Microbiology
Yuesong Weng, Tao Wang, Bin Huang, Hua Yu, Wei Jia, Bin Shan, Fen Qu, Yiwei Tang, Liang Chen, Hong Du
Summary: This study investigated the extent of colistin heteroresistance among CRKP strains in China, revealing a prevalence of 6.2%. It was found that the ST11 clone accounted for 60.7% of the colistin-heteroresistant isolates. The study also showed that heteroresistance could be suppressed by an efflux pump inhibitor and identified the significant role of the PhoPQ pathway in the mechanisms of heteroresistance.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Feiling Wang, Lehui Yi, Fang Ming, Rui Dong, Feng Wang, Ruirui Chen, Xiaoling Hu, Xuri Chen, Bo Sun, Yi-Wei Tang, Yuanfang Zhu, Lijuan Wu
Summary: This study compared the performance of four methods for detecting GBS colonization in rectovaginal specimens, and found that Xpert Xpress GBS had high sensitivity and specificity, as well as a quick and accurate screening process.
MICROBIOLOGY SPECTRUM
(2023)