Role of Nurr1 in the Generation and Differentiation of Dopaminergic Neurons from Stem Cells

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease

(2015) S.-M. Oh et al.   EMBO Molecular Medicine

Human Periapical Cyst–Mesenchymal Stem Cells Differentiate Into Neuronal Cells

(2015) M. Marrelli et al.   JOURNAL OF DENTAL RESEARCH

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease

(2015) Ariadna Laguna et al.   NATURE NEUROSCIENCE

Transcriptional Regulation of Olfactory Bulb Neurogenesis

(2014) Eva Díaz-Guerra et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

NR4A nuclear receptors are orphans but not lonesome

(2014) Kondababu Kurakula et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression

(2014) Jaclyn Nicole Le Grand et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation

(2014) S.-H. Yi et al.   DEVELOPMENT

Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes

(2014) Eva Vergaño-Vera et al.   Developmental Neurobiology

An update on the connections of the ventral mesencephalic dopaminergic complex

(2014) L. Yetnikoff et al.   NEUROSCIENCE

Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons

(2014) Seung-ick Oh et al.   TheScientificWorldJOURNAL

The hypothalamus and periaqueductal gray are the sources of dopamine fibers in the paraventricular nucleus of the thalamus in the rat

(2014) Sa Li et al.   Frontiers in Neuroanatomy

Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation

(2014) Daisuke Doi et al.   Stem Cell Reports

Distinct Modes of Dopamine and GABA Release in a Dual Transmitter Neuron

(2013) M. Borisovska et al.   JOURNAL OF NEUROSCIENCE

Foxa1 and Foxa2 Are Required for the Maintenance of Dopaminergic Properties in Ventral Midbrain Neurons at Late Embryonic Stages

(2013) S. R. W. Stott et al.   JOURNAL OF NEUROSCIENCE

Conditioned medium from human amniotic epithelial cells may induce the differentiation of human umbilical cord blood mesenchymal stem cells into dopaminergic neuron-like cells

(2013) Shu Yang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Nurr1 Represses Tyrosine Hydroxylase Expression via SIRT1 in Human Neural Stem Cells

(2013) Tae Eun Kim et al.   PLoS One

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

(2013) B. Kadkhodaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Roles of Nurr1, Pitx3, and Lmx1a in Neurogenesis and Phenotype Specification of Dopamine Neurons During In Vitro Differentiation of Embryonic Stem Cells

(2013) Sunghoi Hong et al.   STEM CELLS AND DEVELOPMENT

Rapid Generation of Functional Dopaminergic Neurons From Human Induced Pluripotent Stem Cells Through a Single-Step Procedure Using Cell Lineage Transcription Factors

(2013) Ilda Theka et al.   Stem Cells Translational Medicine

In vitro generation of mature dopamine neurons by decreasing and delaying the expression of exogenous Nurr1

(2012) C.-H. Park et al.   DEVELOPMENT

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA

(2012) Nicolas X. Tritsch et al.   NATURE

Direct Regulation of Pitx3 Expression by Nurr1 in Culture and in Developing Mouse Midbrain

(2012) Floriana Volpicelli et al.   PLoS One

The role of NR4A transcription factors in memory formation

(2011) Josh D. Hawk et al.   BRAIN RESEARCH BULLETIN

A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse

(2011) YuHong Fu et al.   Brain Structure & Function

Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells

(2011) Xinjian Liu et al.   CELL RESEARCH

Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency

(2011) S. Vuillermot et al.   GENES BRAIN AND BEHAVIOR

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

(2011) Yong-Hee Rhee et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

(2011) Russell C. Addis et al.   PLoS One

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Molecular Identity of Periglomerular and Short Axon Cells

(2010) E. Kiyokage et al.   JOURNAL OF NEUROSCIENCE

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

“Interneurons” in the olfactory bulb revisited

(2010) Toshio Kosaka et al.   NEUROSCIENCE RESEARCH

Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function and Cell Survival

(2010) Hyun-Seob Lee et al.   STEM CELLS

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons

(2009) F. M. J. Jacobs et al.   DEVELOPMENT

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

(2009) F. M. J. Jacobs et al.   DEVELOPMENT

IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone

(2009) Anahí Hurtado-Chong et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Morphology of dopaminergic amacrine cells in the mouse retina: Independence from homotypic interactions

(2009) Patrick W. Keeley et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

NGFI-B Nuclear Orphan Receptor Nurr1 Interacts with p53 and Suppresses Its Transcriptional Activity

(2009) T. Zhang et al.   MOLECULAR CANCER RESEARCH

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

(2009) Noemi FUSAKI et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease

(2008) Fiona E. O’Keeffe et al.   BRAIN

Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro

(2008) Chang-Hwan Park et al.   FEBS LETTERS

Effects on Differentiation of Embryonic Ventral Midbrain Progenitors by Lmx1a, Msx1, Ngn2, and Pitx3

(2008) L. Roybon et al.   JOURNAL OF NEUROSCIENCE