Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 47, Issue 12, Pages 4158-4160Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01022-09
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- Children's Hospital of Illinois
- William H. Albers Chair of Pediatrics, University of Illinois College of Medicine at Peoria
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We investigated whether methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) isolates with low-level mupirocin resistance can serve as recipients of a pSK41-like plasmid conferring high-level mupirocin resistance without substantial fitness cost. Our results suggest that acquisition of the plasmid conferring high-level mupirocin resistance was not necessarily associated with fitness cost in some MRSA recipients with low-level mupirocin resistance.
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