Article
Cardiac & Cardiovascular Systems
Peng An, Sitong Wan, Yongting Luo, Junjie Luo, Xu Zhang, Shuaishuai Zhou, Teng Xu, Jingjing He, Jeffrey Mechanick, Wen-Chih Wu, Fazheng Ren, Simin Liu
Summary: This study provides a comprehensive and up-to-date evidence-based map on the impact of micronutrients on cardiovascular disease outcomes. It reveals that supplementation of certain micronutrients can benefit cardiometabolic health, highlighting the importance of micronutrient diversity and the balance of benefits and risks.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Clinical Neurology
Laura D. Baker, Heather M. Snyder, Mark A. Espeland, Rachel A. Whitmer, Miia Kivipelto, Nancy Woolard, Jeffrey Katula, Kathryn V. Papp, Jennifer Ventrelle, Sarah Graef, Marcus A. Hill, Scott Rushing, Julia Spell, Laura Lovato, Deborah Felton, Benjamin J. Williams, Mina Ghadimi Nouran, Rema Raman, Tiia Ngandu, Alina Solomon, Sharon Wilmoth, Maryjo L. Cleveland, Jeff D. Williamson, Katherine L. Lambert, Sarah Tomaszewski Farias, Claire E. Day, Christy C. Tangney, Darren R. Gitelman, Olivia Matongo, Terrianne Reynolds, Valory N. Pavlik, Melissa M. Yu, Ashley S. Alexander, Richard Elbein, Ann Marie Mcdonald, Stephen Salloway, Rena R. Wing, Susan Antkowiak, Martha Clare Morris, Maria C. Carrillo
Summary: U.S. POINTER is a 2-year randomized controlled trial in the United States focusing on lifestyle interventions for dementia prevention, with outcomes assessments at baseline and every 6 months, and collaboration with similar trials globally for harmonization and data sharing.
ALZHEIMERS & DEMENTIA
(2023)
Article
Medicine, General & Internal
Aruna Das Pradhan, Robert J. Glynn, Jean-Charles Fruchart, Jean G. MacFadyen, Elaine S. Zaharris, Brendan M. Everett, Stuart E. Campbell, Ryu Oshima, Pierre Amarenco, Dirk J. Blom, Eliot A. Brinton, Robert H. Eckel, Marshall B. Elam, Joao S. Felicio, Henry N. Ginsberg, Assen Goudev, Shun Ishibashi, Jacob Joseph, Tatsuhiko Kodama, Wolfgang Koenig, Lawrence A. Leiter, Alberto J. Lorenzatti, Boris Mankovsky, Nikolaus Marx, Borge G. Nordestgaard, Denes Pall, Kausik K. Ray, Raul D. Santos, Handrean Soran, Andrey Susekov, Michal Tendera, Koutaro Yokote, Nina P. Paynter, Julie E. Buring, Peter Libby, Paul M. Ridker
Summary: In patients with type 2 diabetes and high triglyceride levels, pemafibrate can reduce triglyceride, VLDL cholesterol, remnant cholesterol, and apolipoprotein C-III levels, but does not lower the incidence of cardiovascular events.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Clinical Neurology
Matthew W. McDonald, Matthew S. Jeffers, Lama Issa, Anthony Carter, Allyson Ripley, Lydia M. Kuhl, Cameron Morse, Cesar H. Comin, Bernard J. Jasmin, Baptiste Lacoste, Dale Corbett
Summary: The evidence supports early rehabilitation after stroke to limit disability, with a combination of aerobic and resistance exercise along with resveratrol showing promising results in mitigating cardiovascular and skeletal muscle deconditioning. However, there were no additive effects observed in these experiments, despite the potential benefits of early treatment for poststroke behavioral impairments.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Agronomy
Paul R. Grundy, Gail M. Spargo, Stephen J. Yeates, Kerry L. Bell
Summary: Late winter sowing of cotton can reduce the risk of exposure to unfavorable climate conditions and improve yield; the application of oxodegradable film at sowing has marginal benefits for establishment and crop growth and yield.
FIELD CROPS RESEARCH
(2021)
Review
Cardiac & Cardiovascular Systems
Amedeo Tirandi, Fabrizio Montecucco, Luca Liberale
Summary: The amount of physical activity practiced by people has been decreasing in recent decades, leading to higher risks of atherosclerosis and related cardiovascular events. Regular physical activity has beneficial effects on metabolism and can help prevent cardiovascular diseases. Several studies have found lower levels of plasma lipids in individuals who engage in exercise, but the exact mechanisms by which physical activity modulates lipoproteins are still not fully understood.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Endocrinology & Metabolism
Thomas Yates, Jack A. Sargeant, James A. King, Joe Henson, Charlotte L. Edwardson, Emma Redman, Gaurav S. Gulsin, Emer M. Brady, Ehtasham Ahmad, David J. Stensel, David R. Webb, Gerry P. McCann, Kamlesh Khunti, Melanie J. Davies
Summary: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP-1RA) may reduce physical activity while improving metabolic health.
Article
Public, Environmental & Occupational Health
Nicholas J. SantaBarbara, Roxana Rezai, Samantha Soetenga, Elisa Terry, Catherine L. Carpenter, Warren Scott Comulada
Summary: Based on the survey results, employees prefer workplace wellness programs that focus on improving multiple aspects of physical health, take place in various locations, are administered by a coach who is physically present, occur 2-3 times per week for approximately 60 minutes each time, include a range of intensities, and consist of aerobic exercise and weight training.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Editorial Material
Medicine, General & Internal
John T. Wilkins, Donald M. Lloyd-Jones
Summary: This article reviews different lipid-lowering therapies including traditional statins and ezetimibe, as well as new therapies like PCSK-9 inhibitors, bempedoic acid, icosapent ethyl, and inclisiran, prescribed to reduce cardiovascular risk.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Gerontology
Nicola Brew-Sam, Arul Chib, Arah Ysabelle Fondevilla Torres, Jing Xuan Joshua Ng, Yi Ting Jade Wong, Yeo Sze-G
Summary: The number of falls among older adults is increasing due to global population aging. An integrated communication campaign utilizing mHealth encouraged older adults to exercise and reduce their risk of falling. The campaign was developed with expert interviews, qualitative interviews, and a baseline survey, and the evaluation showed a significant impact on older adults.
JOURNAL OF APPLIED GERONTOLOGY
(2022)
Letter
Medicine, Research & Experimental
Walter M. Chesnut, Scott MacDonald, Carlos Gustavo Wambier
Summary: Research suggests that increased sugar consumption, high caloric intake, and lack of physical exercise are independently associated with COVID-19 mortality, with genetic factors potentially exacerbating the effects of an unhealthy lifestyle. A diet high in sugar combined with low physical activity may lead to elevated blood glucose levels, worsening glucose metabolism, and increasing the risk of severe COVID-19 symptoms.
MEDICAL HYPOTHESES
(2021)
Editorial Material
Environmental Sciences
Jeremy Fyke, Andrew Weaver
Summary: Climate anxiety is increasing due to concerns about the negative consequences of climate change. Taking proactive measures to address individual climate risks may help reduce personal climate anxiety.
NATURE CLIMATE CHANGE
(2023)
Article
Cell Biology
Jae Min Cho, Rajeshwary Ghosh, Sohom Mookherjee, Sihem Boudina, J. David Symons
Summary: During aging, impaired autophagy may contribute to organ dysfunction. However, interventions such as caloric restriction, spermidine, rapamycin, and exercise can restore or enhance autophagic flux, leading to improved cardiac function in relation to aging.
Review
Biochemistry & Molecular Biology
Thembeka A. Nyawo, Carmen Pheiffer, Sithandiwe E. Mazibuko-Mbeje, Sinenhlanhla X. H. Mthembu, Tawanda M. Nyambuya, Bongani B. Nkambule, Hanel Sadie-Van Gijsen, Hans Strijdom, Luca Tiano, Phiwayinkosi V. Dludla
Summary: Excessive epicardial adiposity is emerging as an important risk factor for cardiovascular diseases, and reducing epicardial fat thickness is crucial for attenuating CVD risk in the setting of metabolic disease. Physical exercise can reduce epicardial fat and decrease CVD risk in conditions of metabolic disease.
Article
Computer Science, Interdisciplinary Applications
Shilpa Sethi, Mamta Kathuria, Trilok Kaushik
Summary: During the pandemic, wearing masks is an effective non-pharmaceutical intervention to reduce the risk of infection. A new technique has been proposed to accurately and real-time detect non-mask faces in public spaces, using a combination of one-stage and two-stage detectors to achieve low inference time and high accuracy.
JOURNAL OF BIOMEDICAL INFORMATICS
(2021)