HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers

Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation

(2018) Lillian B. Cohn et al.   NATURE MEDICINE

Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals

(2018) Katherine E. Clarridge et al.   PLoS Pathogens

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

(2017) Guinevere Q. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

(2017) Nina N. Hosmane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART

(2017) Ann Wiegand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized controlled safety/efficacy trial of therapeutic vaccination in HIV-infected individuals who initiated antiretroviral therapy early in infection

(2017) Michael C. Sneller et al.   Science Translational Medicine

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4 + T Cells from Effectively Treated Participants

(2017) Bonnie Hiener et al.   Cell Reports

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

(2017) John K. Bui et al.   PLoS Pathogens

Treatment interruption in chronically HIV-infected patients with an ultralow HIV reservoir

(2016) Ruxandra Calin et al.   AIDS

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy

(2016) Hiromi Imamichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

(2016) Julio C. C. Lorenzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

(2016) Alison L. Hill et al.   PLoS Pathogens

Post-Treatment Controllers: Role in HIV “Cure” Research

(2016) Leslie R. Cockerham et al.   Current HIV/AIDS Reports

HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report

(2016) Pierre Frange et al.   Lancet HIV

A low HIV-DNA level in peripheral blood mononuclear cells at antiretroviral treatment interruption predicts a higher probability of maintaining viral control

(2015) Lambert Assoumou et al.   AIDS

How often does treatment of primary HIV lead to post-treatment control?

(2015) Janine Maenza et al.   ANTIVIRAL THERAPY

Post-treatment control of HIV infection

(2015) Jessica M. Conway et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation

(2014) Timothy J. Henrich et al.   ANNALS OF INTERNAL MEDICINE

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

(2014) Alison L. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection

(2014) T. A. Wagner et al.   SCIENCE

Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

(2014) F. Maldarelli et al.   SCIENCE

HIV-1 DNA predicts disease progression and post-treatment virological control

(2014) James P Williams et al.   eLife

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

Duration of HIV-1 Viral Suppression on Cessation of Antiretroviral Therapy in Primary Infection Correlates with Time on Therapy

(2013) Wolfgang Stöhr et al.   PLoS One

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

(2013) Asier Sáez-Cirión et al.   PLoS Pathogens

HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy

(2012) Cécile Goujard et al.   ANTIVIRAL THERAPY

Immunovirologic Control 24 Months After Interruption of Antiretroviral Therapy Initiated Close to HIV Seroconversion

(2012) Sara Lodi et al.   ARCHIVES OF INTERNAL MEDICINE

Correlates of Protective Cellular Immunity Revealed by Analysis of Population-Level Immune Escape Pathways in HIV-1

(2012) J. M. Carlson et al.   JOURNAL OF VIROLOGY

Immune and Viral Correlates of “Secondary Viral Control” after Treatment Interruption in Chronically HIV-1 Infected Patients

(2012) Ellen Van Gulck et al.   PLoS One

Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy

(2011) Maria Salgado et al.   Retrovirology

Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection

(2010) Laurent Hocqueloux et al.   AIDS

AIDS Clinical Trials Group 5197: A Placebo‐Controlled Trial of Immunization of HIV‐1–Infected Persons with a Replication‐Deficient Adenovirus Type 5 Vaccine Expressing the HIV‐1 Core Protein

(2010) Robert T. Schooley et al.   JOURNAL OF INFECTIOUS DISEASES

Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase

(2009) Mary Kearney et al.   AIDS

Antiretroviral therapy in acute and recent HIV infection: a prospective multicenter stratified trial of intentionally interrupted treatment

(2009) Paul Volberding et al.   AIDS

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE