Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer
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Title
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume -, Issue -, Pages -
Publisher
American Society for Clinical Investigation
Online
2018-08-27
DOI
10.1172/jci99481
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Note: Only part of the references are listed.- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
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- (2017) Dan R Laks et al. NEURO-ONCOLOGY
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- (2016) Zhihao Wang et al. CANCER LETTERS
- Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
- (2016) Richard Marcotte et al. CELL
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer
- (2015) Joseph A. Sparano et al. JOURNAL OF CLINICAL ONCOLOGY
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- DNA methylation pathways and their crosstalk with histone methylation
- (2015) Jiamu Du et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance
- (2015) P Khongkow et al. ONCOGENE
- Elevated MARCKS phosphorylation contributes to unresponsiveness of breast cancer to paclitaxel treatment
- (2015) Ching-Hsien Chen et al. Oncotarget
- EMT, CTCs and CSCs in tumor relapse and drug-resistance
- (2015) Abhisek Mitra et al. Oncotarget
- FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
- (2014) D-W Wu et al. ONCOGENE
- Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy
- (2013) James V. Alvarez et al. CANCER CELL
- Poised with purpose: Cell plasticity enhances tumorigenicity
- (2013) Nemanja D Marjanovic et al. CELL CYCLE
- The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma
- (2013) E Sánchez-Tilló et al. CELL DEATH AND DIFFERENTIATION
- A double take on bivalent promoters
- (2013) P. Voigt et al. GENES & DEVELOPMENT
- Epithelial-mesenchymal plasticity in carcinoma metastasis
- (2013) J. H. Tsai et al. GENES & DEVELOPMENT
- The epigenetics of epithelial-mesenchymal plasticity in cancer
- (2013) Wai Leong Tam et al. NATURE MEDICINE
- Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT
- (2013) Jiaxin Tan et al. TOXICOLOGY LETTERS
- The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
- (2012) Ali Shilatifard Annual Review of Biochemistry
- Regulation of Transcription Factor Twist Expression by the DNA Architectural Protein High Mobility Group A2 during Epithelial-to-Mesenchymal Transition
- (2012) E-Jean Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer
- (2012) Chenfang Dong et al. JOURNAL OF CLINICAL INVESTIGATION
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells
- (2012) N Chapman-Rothe et al. ONCOGENE
- The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU
- (2011) Christina Leah B. Kline et al. APOPTOSIS
- Prostate Apoptosis Response 4 (Par-4), a Novel Substrate of Caspase-3 during Apoptosis Activation
- (2011) P. Chaudhry et al. MOLECULAR AND CELLULAR BIOLOGY
- Twist2 contributes to breast cancer progression by promoting an epithelial–mesenchymal transition and cancer stem-like cell self-renewal
- (2011) X Fang et al. ONCOGENE
- Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters
- (2011) M Saxena et al. Cell Death & Disease
- Structural Signature of the MYPT1−PP1 Interaction
- (2010) Anderson S. Pinheiro et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
- (2010) J. H. Taube et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Par-4 Is an Essential Downstream Target of DAP-like Kinase (Dlk) in Dlk/Par-4–mediated Apoptosis
- (2009) Meike Boosen et al. MOLECULAR BIOLOGY OF THE CELL
- Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis
- (2008) Jayashree Joshi et al. EMBO JOURNAL
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
- Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer
- (2007) Farhad Vesuna et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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