RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity

RASA1Mutations and Associated Phenotypes in 68 Families with Capillary Malformation-Arteriovenous Malformation

(2013) Nicole Revencu et al.   HUMAN MUTATION

Phenotypic variability in a family with capillary malformations caused by a mutation in the RASA1 gene

(2012) Robert S. de Wijn et al.   European Journal of Medical Genetics

'In parallel' interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow

(2012) T. Zygmunt et al.   JOURNAL OF CELL SCIENCE

RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

(2012) Philip E. Lapinski et al.   JOURNAL OF CLINICAL INVESTIGATION

Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis

(2011) J. Choi et al.   DEVELOPMENT

EphrinA/EphA signal facilitates insulin-like growth factor-I–induced myogenic differentiation through suppression of the Ras/extracellular signal–regulated kinase 1/2 cascade in myoblast cell lines

(2011) Masayoshi Minami et al.   MOLECULAR BIOLOGY OF THE CELL

Sirolimus for the treatment of complicated vascular anomalies in children

(2011) Adrienne M. Hammill et al.   PEDIATRIC BLOOD & CANCER

Vascular Anomalies: Current Overview of the Field

(2010) Arin K. Greene   CLINICS IN PLASTIC SURGERY

Pathogenesis of Vascular Anomalies

(2010) Laurence M. Boon et al.   CLINICS IN PLASTIC SURGERY

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

(2010) Sudarshan Anand et al.   NATURE MEDICINE

Extracranial Arteriovenous Malformations: Natural Progression and Recurrenceafter Treatment

(2010) Allen S. Liu et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

(2009) Teemu T. Junttila et al.   CANCER CELL

Arterial–Venous Specification During Development

(2009) Matthew R. Swift et al.   CIRCULATION RESEARCH

A mechanosensitive transcriptional mechanism that controls angiogenesis

(2009) Akiko Mammoto et al.   NATURE

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis

(2009) Kip M Connor et al.   Nature Protocols

Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors

(2009) Catherine Lam et al.   PEDIATRIC BLOOD & CANCER

Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation

(2009) S. P. Herbert et al.   SCIENCE

P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling

(2008) Perayot Pamonsinlapatham et al.   BIOCHIMIE

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

(2008) V. Serra et al.   CANCER RESEARCH

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

(2008) Y. H. Kim et al.   DEVELOPMENT

Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused byRASA1 mutations

(2008) Nicole Revencu et al.   HUMAN MUTATION

Ephrin-B2-induced Cleavage of EphB2 Receptor Is Mediated by Matrix Metalloproteinases to Trigger Cell Repulsion

(2008) Kai-Ti Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY