Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Fatty Acid Synthase Modulates Intestinal Barrier Function through Palmitoylation of Mucin 2

(2012) Xiaochao Wei et al.   Cell Host & Microbe

Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle

(2012) Deborah M. Muoio et al.   Cell Metabolism

Insulin Resistance in the Defense against Obesity

(2012) Alan R. Saltiel   Cell Metabolism

Inhibiting Adipose Tissue Lipogenesis Reprograms Thermogenesis and PPARγ Activation to Decrease Diet-Induced Obesity

(2012) Irfan J. Lodhi et al.   Cell Metabolism

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Skeletal muscle lipid flux: running water carries no poison

(2011) Katsuhiko Funai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Activating and Deactivating Roles of Lipid Bilayers on the Ca2+-ATPase/Phospholamban Complex

(2011) Martin Gustavsson et al.   BIOCHEMISTRY

Fatty acid synthase and liver triglyceride metabolism: Housekeeper or messenger?

(2011) Anne P.L. Jensen-Urstad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

C2 Domain-Containing Phosphoprotein CDP138 Regulates GLUT4 Insertion into the Plasma Membrane

(2011) Xiangyang Xie et al.   Cell Metabolism

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

The nuclear receptor PPAR /  programs muscle glucose metabolism in cooperation with AMPK and MEF2

(2011) Z. Gan et al.   GENES & DEVELOPMENT

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Fatty Acid Synthase Modulates Homeostatic Responses to Myocardial Stress

(2011) Babak Razani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

(2011) Sanjeewa A. Goonasekera et al.   JOURNAL OF CLINICAL INVESTIGATION

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

(2011) Suneng Fu et al.   NATURE

Diabetes Mellitus, Fasting Glucose, and Risk of Cause-Specific Death

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Metabolic Inflexibility in Skeletal Muscle Among Individuals With Increasing Insulin Resistance

(2011) Anneke Jans et al.   Obesity

Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes

(2011) M. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum

(2010) David H. MacLennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

(2010) D. P. Y. Koonen et al.   DIABETES

De NovoLipogenesis Maintains Vascular Homeostasis through Endothelial Nitric-oxide Synthase (eNOS) Palmitoylation

(2010) Xiaochao Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage Fatty-acid Synthase Deficiency Decreases Diet-induced Atherosclerosis

(2010) Jochen G. Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipoexpediency: de novo lipogenesis as a metabolic signal transmitter

(2010) Irfan J. Lodhi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

(2009) Manu V. Chakravarthy et al.   CELL

Inhibition of Contraction-Stimulated AMP-Activated Protein Kinase Inhibits Contraction-Stimulated Increases in PAS-TBC1D1 and Glucose Transport Without Altering PAS-AS160 in Rat Skeletal Muscle

(2009) K. Funai et al.   DIABETES

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

Ablation of AMP-Activated Protein Kinase  2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice

(2008) N. Fujii et al.   DIABETES

Skeletal Muscle-Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues

(2008) H. Wang et al.   DIABETES

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

The Crystal Structure of a Mammalian Fatty Acid Synthase

(2008) T. Maier et al.   SCIENCE