RNA-guided diagnostics and therapeutics for next-generation individualized nanomedicine

Multicolor microRNA FISH effectively differentiates tumor types

(2013) Neil Renwick et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers

(2013) Alayne L Brunner et al.   GENOME BIOLOGY

Photonic Gene Circuits by Optically Addressable siRNA-Au Nanoantennas

(2012) Somin Eunice Lee et al.   ACS Nano

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression

(2012) G. Zardo et al.   BLOOD

Transcriptional targeting by microRNA-Polycomb complexes: A novel route in cell fate determination

(2012) Giuseppe Zardo et al.   CELL CYCLE

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

Uncovering the role of genomic “dark matter” in human disease

(2012) Lance Martin et al.   JOURNAL OF CLINICAL INVESTIGATION

Target mRNA inhibition by oligonucleotide drugs in man

(2012) H. L. Lightfoot et al.   NUCLEIC ACIDS RESEARCH

Detection of Long Non-Coding RNA in Archival Tissue: Correlation with Polycomb Protein Expression in Primary and Metastatic Breast Carcinoma

(2012) Karen M. Chisholm et al.   PLoS One

Epigenetic Regulation by Long Noncoding RNAs

(2012) J. T. Lee   SCIENCE

Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4

(2012) Y. Ren et al.   Science Translational Medicine

Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

(2012) Anna L Olsen et al.   Molecular Therapy-Nucleic Acids

Phenotype-defining functions of multiple non-coding RNA pathways

(2011) Gennadi V. Glinsky   CELL CYCLE

Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders

(2011) Anna B. Glinskii et al.   CELL CYCLE

Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders

(2011) Anna B. Glinskii et al.   CELL CYCLE

Active Surveillance Program for Prostate Cancer: An Update of the Johns Hopkins Experience

(2011) Jeffrey J. Tosoian et al.   JOURNAL OF CLINICAL ONCOLOGY

DNA Zipper-Based Tweezers

(2011) Preston B. Landon et al.   LANGMUIR

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Integrated analysis of preclinical data to support the design of the first in man study of LY2181308, a second generation antisense oligonucleotide

(2010) Sophie Callies et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Tumor Site-Specific Silencing of NF- B p65 by Targeted Hollow Gold Nanosphere-Mediated Photothermal Transfection

(2010) W. Lu et al.   CANCER RESEARCH

Outcomes in Localized Prostate Cancer: National Prostate Cancer Register of Sweden Follow-up Study

(2010) P. Stattin et al.   JNCI-Journal of the National Cancer Institute

Mortality results from the Göteborg randomised population-based prostate-cancer screening trial

(2010) Jonas Hugosson et al.   LANCET ONCOLOGY

Laser-Activated Gene Silencing via Gold Nanoshell−siRNA Conjugates

(2009) Gary B. Braun et al.   ACS Nano

Screening and Prostate-Cancer Mortality in a Randomized European Study

(2009) Fritz H. Schröder et al.   NEW ENGLAND JOURNAL OF MEDICINE