Unraveling the mystery of the hygiene hypothesis through Helicobacter pylori infection

DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori–specific immune tolerance, and asthma protection

(2012) Mathias Oertli et al.   JOURNAL OF CLINICAL INVESTIGATION

Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells

(2011) Isabelle C. Arnold et al.   JOURNAL OF CLINICAL INVESTIGATION

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

(2010) Tomohiro Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Helicobacter pylori invades the gastric mucosa and translocates to the gastric lymph nodes

(2008) Takashi Ito et al.   LABORATORY INVESTIGATION