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Title
Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 122, Issue 4, Pages 1262-1270
Publisher
American Society for Clinical Investigation
Online
2012-03-19
DOI
10.1172/jci61919
References
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Related references
Note: Only part of the references are listed.- mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
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- (2010) Pankaj Kapahi et al. Cell Metabolism
- Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
- (2010) Bin Dong et al. JOURNAL OF LIPID RESEARCH
- mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
- (2010) Shomit Sengupta et al. NATURE
- Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine
- (2009) Hai Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
- (2009) J. C. Y. Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor
- (2009) Noam Zelcer et al. SCIENCE
- Mammalian Target of Rapamycin Inhibitor Dyslipidemia in Kidney Transplant Recipients
- (2008) B. L. Kasiske et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Rapamycin down-regulates LDL-receptor expression independently of SREBP-2
- (2008) Laura J. Sharpe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis
- (2008) Sudha B. Biddinger et al. Cell Metabolism
- Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
- (2008) M. Frank-Kamenetsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR−/− mice despite severe hypercholesterolemia
- (2007) Marc A. Mueller et al. ATHEROSCLEROSIS
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