Adherent-invasive E. coli in Crohn disease: bacterial “agent provocateur”

Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae

(2011) Benoit Chassaing et al.   JOURNAL OF CLINICAL INVESTIGATION

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Complete Genome Sequence of Crohn's Disease-Associated Adherent-Invasive E. coli Strain LF82

(2010) Sylvie Miquel et al.   PLoS One

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

(2009) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches

(2009) F. Barreau et al.   GUT

Crohn's disease adherent-invasiveEscherichia colicolonize and induce strong gut inflammation in transgenic mice expressing human CEACAM

(2009) Frédéric A. Carvalho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Reduced  -defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease

(2008) L A Simms et al.   GUT

Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease

(2007) Hiromasa Takaishi et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY