SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Automated Network Analysis Identifies Core Pathways in Glioblastoma

(2010) Ethan Cerami et al.   PLoS One

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

(2010) W. R. Wiedemeyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the NG2 proteoglycan in glioma progression

(2010) William B. Stallcup et al.   Cell Adhesion & Migration

Protein tyrosine phosphatases in glioma biology

(2009) Anna C. Navis et al.   ACTA NEUROPATHOLOGICA

Recent Insights into PDGF-Induced Gliomagenesis

(2009) Filippo Calzolari et al.   BRAIN PATHOLOGY

Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas

(2009) O Martinho et al.   BRITISH JOURNAL OF CANCER

Protein tyrosine phosphatase SHP-2: A proto-oncogene product that promotes Ras activation

(2009) Takashi Matozaki et al.   CANCER SCIENCE

The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells

(2009) Yi Zhan et al.   EXPERIMENTAL CELL RESEARCH

Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity

(2009) Jia-Jean Yiin et al.   NEURO-ONCOLOGY

Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations

(2009) Cameron Brennan et al.   PLoS One

The tyrosine phosphatase Shp2 (PTPN11) in cancer

(2008) Gordon Chan et al.   CANCER AND METASTASIS REVIEWS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE