Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia

A major role of TGF- 1 in the homing capacities of murine hematopoietic stem cell/progenitors

(2010) C. Capron et al.   BLOOD

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value

(2010) A. E. Smith et al.   BLOOD

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation

(2010) Xiaoying Bai et al.   CELL

Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

(2010) Grant A. Challen et al.   Cell Stem Cell

Negative control of Smad activity by ectodermin/Tif1  patterns the mammalian embryo

(2010) L. Morsut et al.   DEVELOPMENT

Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

(2010) Alexander Kohlmann et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms

(2010) O Kosmider et al.   LEUKEMIA

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

(2010) Myunggon Ko et al.   NATURE

Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells

(2010) J Paggetti et al.   ONCOGENE

Histone modification levels are predictive for gene expression

(2010) R. Karlic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations of polycomb-associated geneASXL1in myelodysplastic syndromes and chronic myelomonocytic leukaemia

(2009) Véronique Gelsi-Boyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

(2009) O. Kosmider et al.   HAEMATOLOGICA

iNKT cell development is orchestrated by different branches of TGF-β signaling

(2009) Jean-Marc Doisne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

(2009) Pierre Fenaux et al.   LANCET ONCOLOGY

RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation

(2009) M-C Kuo et al.   LEUKEMIA

Inactivation of TIF1γ Cooperates with KrasG12D to Induce Cystic Tumors of the Pancreas

(2009) David F. Vincent et al.   PLoS Genetics

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

(2008) J. W. Tyner et al.   BLOOD

Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1genes

(2008) Véronique Gelsi-Boyer et al.   BMC CANCER

250K Single Nucleotide Polymorphism Array Karyotyping Identifies Acquired Uniparental Disomy and Homozygous Mutations, Including Novel Missense Substitutions of c-Cbl, in Myeloid Malignancies

(2008) A. J. Dunbar et al.   CANCER RESEARCH

Generation of mice with a conditional allele forTrim33

(2008) Jieun Kim et al.   GENESIS

Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia

(2008) P D Emanuel   LEUKEMIA