Uric acid transport and disease

Hyperuricemia and risk of stroke: A systematic review and meta-analysis

(2009) Seo Young Kim et al.   ARTHRITIS AND RHEUMATISM

Elevated Serum Uric Acid is an Independent Predictor for Cardiovascular Events in Patients With Severe Coronary Artery Stenosis

(2009) Takafumi Okura et al.   CIRCULATION JOURNAL

Age and origin of the G774A mutation in SLC22A12 causing renal hypouricemia in Japanese

(2009) K Ichida et al.   CLINICAL GENETICS

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

(2009) Nicola L. Beer et al.   HUMAN MOLECULAR GENETICS

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia

(2009) D. Dinour et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease

(2009) Klaus Stark et al.   PLoS One

Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy

(2009) F. Preitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

(2009) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?

(2009) Angelo L Gaffo et al.   ARTHRITIS RESEARCH & THERAPY

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

(2009) Melanie Kolz et al.   PLoS Genetics

Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia

(2008) Hirotaka Matsuo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

(2008) Chris Wallace et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

(2008) Sergey Zharikov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Long-term Cardiovascular Mortality Among Middle-aged Men With Gout

(2008) Eswar Krishnan   ARCHIVES OF INTERNAL MEDICINE

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

(2008) A A K El-Sheikh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

(2008) M. Orho-Melander et al.   DIABETES

Sex-Specific Association of the Putative Fructose Transporter SLC2A9 Variants With Uric Acid Levels Is Modified by BMI

(2008) A. Brandstatter et al.   DIABETES CARE

Serum uric acid and its association with metabolic syndrome and carotid atherosclerosis in obese children

(2008) Lucia Pacifico et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Effect of Allopurinol on Blood Pressure of Adolescents With Newly Diagnosed Essential Hypertension

(2008) Daniel I. Feig et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of a New Urate and High Affinity Nicotinate Transporter, hOAT10 (SLC22A13)

(2008) Andrew Bahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans

(2008) Naohiko Anzai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

(2008) Abbas Dehghan et al.   LANCET

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

(2008) Angela Döring et al.   NATURE GENETICS

Uric Acid and Cardiovascular Risk

(2008) Daniel I. Feig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidative imbalance in idiopathic renal hypouricemia

(2008) Kazunari Kaneko et al.   PEDIATRIC NEPHROLOGY

Developments in the scientific and clinical understanding of gout

(2008) Alexander So   ARTHRITIS RESEARCH & THERAPY

Mutations in the SLC2A9 Gene Cause Hyperuricosuria and Hyperuricemia in the Dog

(2008) Danika Bannasch et al.   PLoS Genetics

SLC2A9 Is a High-Capacity Urate Transporter in Humans

(2008) Mark J Caulfield et al.   PLOS MEDICINE

Uric acid level and its association with carotid intima–media thickness in patients with hypertension

(2007) Yusuf Tavil et al.   ATHEROSCLEROSIS

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane

(2007) M. Huls et al.   KIDNEY INTERNATIONAL