Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation

Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy

(2010) Izhak Kehat et al.   Annals of the New York Academy of Sciences

Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration

(2009) Rozanne Arulanandam et al.   EXPERIMENTAL CELL RESEARCH

Malignant Diseases in Noonan Syndrome and Related Disorders

(2009) Henrik Hasle   HORMONE RESEARCH

Cardiac hypertrophy: Targeting Raf/MEK/ERK1/2-signaling

(2009) Kristina Lorenz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Negative Regulation of Stat3 by ActivatingPTPN11Mutants Contributes to the Pathogenesis of Noonan Syndrome and Juvenile Myelomonocytic Leukemia

(2009) Wenjun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The subcellular localization of MEK and ERK—A novel nuclear translocation signal (NTS) paves a way to the nucleus

(2009) Eldar Zehorai et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair

(2009) Viviana Cordeddu et al.   NATURE GENETICS

A restricted spectrum of NRAS mutations causes Noonan syndrome

(2009) Ion C Cirstea et al.   NATURE GENETICS

Molecular targets and regulators of cardiac hypertrophy

(2009) Agrawal Rohini et al.   PHARMACOLOGICAL RESEARCH

Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development

(2009) T. Nakamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations

(2009) T. Nakamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation

(2009) T. Araki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histology Atlas of the Developing Mouse Heart with Emphasis on E11.5 to E18.5

(2009) Saija M. Savolainen et al.   TOXICOLOGIC PATHOLOGY

Angiotensin II Activates Signal Transducer and Activators of Transcription 3 via Rac1 in Atrial Myocytes and Fibroblasts

(2008) Chia-Ti Tsai et al.   CIRCULATION

Body Surface Area Prediction in Normal, Hypermuscular, and Obese Mice

(2008) Michael C. Cheung et al.   JOURNAL OF SURGICAL RESEARCH

Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome

(2008) M. Krenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA