Intravenous Immunoglobulin (IVIG) Treatment Exerts Antioxidant and Neuropreservatory Effects in Preclinical Models of Alzheimer’s Disease

Lessons from a BACE1 inhibitor trial: Off-site but not off base

(2014) Debomoy K. Lahiri et al.   Alzheimers & Dementia

Intravenous Immunoglobulin Reduces Tau Pathology and Preserves Neuroplastic Gene Expression in the 3xTg Mouse Model of Alzheimer’s Disease

(2014) Scott Counts et al.   Current Alzheimer Research

Intravenous Immunoglobulin Treatment Preserves and Protects Primary Rat Hippocampal Neurons and Primary Human Brain Cultures Against Oxidative Insults

(2014) Debomoy Lahiri et al.   Current Alzheimer Research

Effect of IVIg in preserving human primary neurons and protecting them against oxidative stress

(2013) Debomoy Lahiri et al.   Alzheimers & Dementia

SnapShot: Pathobiology of Alzheimer's Disease

(2013) Dennis J. Selkoe   CELL

Intracranial Injection of Gammagard, a Human IVIg, Modulates the Inflammatory Response of the Brain and Lowers A  in APP/PS1 Mice Along a Different Time Course than Anti-A  Antibodies

(2013) T. L. Sudduth et al.   JOURNAL OF NEUROSCIENCE

Immunotherapy for Alzheimer’s Disease

(2013) Martin R. Farlow et al.   NEUROLOGIC CLINICS

MicroRNA-153 Physiologically Inhibits Expression of Amyloid-β Precursor Protein in Cultured Human Fetal Brain Cells and Is Dysregulated in a Subset of Alzheimer Disease Patients

(2012) Justin M. Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease

(2012) Lakshman Puli et al.   Journal of Neuroinflammation

Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease

(2011) Scott E. Counts et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Rivastigmine Lowers Aβ and Increases sAPPα Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons

(2011) Jason A. Bailey et al.   PLoS One

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

Intravenous Immunoglobulins as a Treatment for Alzheimerʼs Disease

(2010) Richard Dodel et al.   DRUGS

Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-l-cysteine treatment in the neuronal culture and APP-Tg mouse model

(2010) Balmiki Ray et al.   JOURNAL OF NEUROCHEMISTRY

Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease

(2010) Johanna Magga et al.   Journal of Neuroinflammation

The Perils of Alzheimers Drug Development

(2009) Lon Schneider et al.   Current Alzheimer Research

A novel effect of rivastigmine on pre-synaptic proteins and neuronal viability in a neurodegeneration model of fetal rat primary cortical cultures and its implication in Alzheimer’s disease

(2009) Jason A. Bailey et al.   JOURNAL OF NEUROCHEMISTRY

Memantine lowers amyloid-β peptide levels in neuronal cultures and in APP/PS1 transgenic mice

(2009) George M. Alley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases

(2009) D K Lahiri et al.   MOLECULAR PSYCHIATRY

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET

18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease

(2008) Norman R. Relkin et al.   NEUROBIOLOGY OF AGING