Fc Glycan-Modulated Immunoglobulin G Effector Functions

Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo

(2014) Inessa Schwab et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

(2013) R. Kapur et al.   BLOOD

T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

(2013) Constanze Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

(2013) Margaret E. Ackerman et al.   JOURNAL OF CLINICAL INVESTIGATION

Dissecting the Molecular Mechanism of IVIg Therapy: The Interaction between Serum IgG and DC-SIGN is Independent of Antibody Glycoform or Fc Domain

(2013) Xiaojie Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1

(2012) Inessa Schwab et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tolerance induction with T cell–dependent protein antigens induces regulatory sialylated IgGs

(2012) Carolin M. Oefner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases

(2012) Erwin W. Gelfand   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms and principles of N-linked protein glycosylation

(2011) Flavio Schwarz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mannose-binding lectin does not explain the course and outcome of pregnancy in rheumatoid arthritis

(2011) Fleur E van de Geijn et al.   ARTHRITIS RESEARCH & THERAPY

Passively Administered Pooled Human Immunoglobulins Exert IL-10 Dependent Anti-Inflammatory Effects that Protect against Fatal HSV Encephalitis

(2011) Chandran Ramakrishna et al.   PLoS Pathogens

Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer

(2010) Teemu T. Junttila et al.   CANCER RESEARCH

IgG Fc N-Glycosylation Changes in Lambert-Eaton Myasthenic Syndrome and Myasthenia Gravis

(2010) Maurice H. J. Selman et al.   JOURNAL OF PROTEOME RESEARCH

Branch-Specific Sialylation of IgG-Fc Glycans by ST6Gal-I

(2009) Adam W. Barb et al.   BIOCHEMISTRY

Emerging methods for the production of homogeneous human glycoproteins

(2009) Jamie R Rich et al.   Nature Chemical Biology

Impaired inhibitory Fc  receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy

(2009) B. Tackenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgG glycosylation analysis

(2009) Carolin Huhn et al.   PROTEOMICS

Anti-Inflammatory Actions of Intravenous Immunoglobulin

(2008) Falk Nimmerjahn et al.   Annual Review of Immunology

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

(2008) A. S. De Groot et al.   BLOOD

Identification of a receptor required for the anti-inflammatory activity of IVIG

(2008) R. M. Anthony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mannose-binding lectin polymorphisms are not associated with rheumatoid arthritis--confirmation in two large cohorts

(2008) F. E. van de Geijn et al.   RHEUMATOLOGY

Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc

(2008) R. M. Anthony et al.   SCIENCE

Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study

(2008) Koert M Dolman et al.   ARTHRITIS RESEARCH & THERAPY