Journal
JOURNAL OF CLINICAL IMMUNOLOGY
Volume 34, Issue 5, Pages 544-547Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10875-014-0036-1
Keywords
Brown recluse spider; systemic loxoscelism; hemophagocytic lymphohistiocytosis (HLH); Loxosceles reclusa
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Funding
- NCATS NIH HHS [UL1 TR000077] Funding Source: Medline
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Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We present a case of a 10-year-old male that developed presumed systemic loxoscelism, secondary hemophagocytic lymphohistiocytosis with hepatic dysfunction and renal failure. He was treated with dexamethasone and made a full recovery.
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