Gain and Loss of T Cell Subsets in Old Age—Age-Related Reshaping of the T Cell Repertoire

Homeostasis of the Naive CD4+ T Cell Compartment during Aging

(2014) R. D. Kilpatrick et al.   JOURNAL OF IMMUNOLOGY

Clonal Expansions and Loss of Receptor Diversity in the Naive CD8 T Cell Repertoire of Aged Mice

(2014) M. Ahmed et al.   JOURNAL OF IMMUNOLOGY

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

(2010) Matthias Hackl et al.   AGING CELL

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Emerging strategies to boost thymic function

(2010) Georg A Holländer et al.   CURRENT OPINION IN PHARMACOLOGY

Human cytomegalovirus-specific CD8+ T-cell expansions contain long-lived cells that retain functional capacity in both young and elderly subjects

(2010) Diana L. Wallace et al.   IMMUNOLOGY

Novel mechanism of signaling by CD28

(2010) Elisa Bjørgo et al.   IMMUNOLOGY LETTERS

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Evidence for microRNA-mediated regulation in rheumatic diseases

(2009) X Luo et al.   ANNALS OF THE RHEUMATIC DISEASES

Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms

(2009) E.A. Dunlop et al.   CELLULAR SIGNALLING

Accelerated Telomere Shortening in Leukocyte Subpopulations of Patients With Coronary Heart Disease

(2009) Ioakim Spyridopoulos et al.   CIRCULATION

Rejuvenation of the aging T cell compartment

(2009) Amanda M Holland et al.   CURRENT OPINION IN IMMUNOLOGY

Effects of aging on T cell function

(2009) Laura Haynes et al.   CURRENT OPINION IN IMMUNOLOGY

Polyamine-rich food decreases age-associated pathology and mortality in aged mice

(2009) Kuniyasu Soda et al.   EXPERIMENTAL GERONTOLOGY

Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation

(2009) Anis Larbi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Evidence of premature immune aging in patients thymectomized during early childhood

(2009) Delphine Sauce et al.   JOURNAL OF CLINICAL INVESTIGATION

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Strong Dietary Restrictions Protect Drosophila against Anoxia/Reoxygenation Injuries

(2009) Paul Vigne et al.   PLoS One

High antigen levels are the cause of T cell exhaustion during chronic viral infection

(2009) S. N. Mueller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccination in the elderly: an immunological perspective

(2009) Wilbur H. Chen et al.   TRENDS IN IMMUNOLOGY

CD28− T cells: their role in the age-associated decline of immune function

(2009) Nan-ping Weng et al.   TRENDS IN IMMUNOLOGY

Cytomegalovirus Infection Causes an Increase of Arterial Blood Pressure

(2009) Jilin Cheng et al.   PLoS Pathogens

Microarray analysis reveals similarity between CD8+CD28− T cells from young and elderly persons, but not of CD8+CD28+ T cells

(2008) Lutfan Lazuardi et al.   BIOGERONTOLOGY

Non-regulatory CD8+CD45RO+CD25+ T-lymphocytes may compensate for the loss of antigen-inexperienced CD8+CD45RA+ T-cells in old age

(2008) Dietmar Herndler-Brandstetter et al.   BIOLOGICAL CHEMISTRY

Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets

(2008) S. Kohler et al.   BLOOD

Thymectomy in early childhood: Significant alterations of the CD4+CD45RA+CD62L+ T cell compartment in later life

(2008) Martina Prelog et al.   CLINICAL IMMUNOLOGY

Biology of Immune Responses to Vaccines in Elderly Persons

(2008) Birgit Weinberger et al.   CLINICAL INFECTIOUS DISEASES

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

(2008) Johanna Kober et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aging of hematopoietic stem cells is regulated by the stem cell niche

(2008) Wolfgang Wagner et al.   EXPERIMENTAL GERONTOLOGY

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

(2008) Christopher M. Snyder et al.   IMMUNITY

Can the Immune System Still Be Efficient in the Elderly? An Immunological and Immunoendocrine Therapeutic Perspective

(2008) Gerald Pfister et al.   NEUROIMMUNOMODULATION

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and  1 and  3 integrins

(2008) G. L. Bentz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNAs and the immune response

(2008) Mark A. Lindsay   TRENDS IN IMMUNOLOGY

CD95-mediated apoptosis in naïve, central and effector memory subsets of CD4+ and CD8+ T cells in aged humans

(2007) Sudhir Gupta et al.   EXPERIMENTAL GERONTOLOGY