Neonatal Fc Receptor: From Immunity to Therapeutics

Activation of the JAK/STAT-1 Signaling Pathway by IFN-  Can Down-Regulate Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG

(2014) X. Liu et al.   JOURNAL OF IMMUNOLOGY

The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner

(2010) Kyosuke Nakata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

X-ray Crystal Structures of Monomeric and Dimeric Peptide Inhibitors in Complex with the Human Neonatal Fc Receptor, FcRn

(2010) Adam R. Mezo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and Structure−Activity Relationships of Dimeric Peptide Antagonists of the Human Immunoglobulin G−Human Neonatal Fc Receptor (IgG−FcRn) Interaction

(2010) Kevin A. McDonnell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective transport of IgE into ovine mammary secretions

(2010) B.C. Hine et al.   RESEARCH IN VETERINARY SCIENCE

Investigation of the Influence of FcRn on the Distribution of IgG to the Brain

(2009) Amit Garg et al.   AAPS Journal

Expression and immunohistochemical localization of the neonatal Fc receptor (FcRn) in the mammary glands of the Egyptian water buffalo

(2009) Ahmed Sayed-Ahmed et al.   ACTA HISTOCHEMICA

An interspecies comparison of placental antibody transfer: New insights into developmental toxicity testing of monoclonal antibodies

(2009) Nele Pentšuk et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics

(2009) Jan Terje Andersen et al.   Drug Metabolism and Pharmacokinetics

An FcRn-Dependent Role for Anti-flagellin Immunoglobulin G in Pathogenesis of Colitis in Mice

(2009) Kanna Kobayashi et al.   GASTROENTEROLOGY

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG

(2009) Timothy T. Kuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding

(2009) Jan Terje Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

(2009) Salit Tzaban et al.   JOURNAL OF CELL BIOLOGY

FcRn in the Yolk Sac Endoderm of Mouse Is Required for IgG Transport to Fetus

(2009) J. Kim et al.   JOURNAL OF IMMUNOLOGY

IgG is transported across the mouse yolk sac independently of FcγRIIb

(2009) Sudhasri Mohanty et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG

(2009) M. Sarav et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

(2009) Héctor Pérez Montoyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization with Cry1Ac fromBacillus ThuringiensisIncreases Intestinal IgG Response and Induces the Expression of FcRn in the Intestinal Epithelium of Adult Mice

(2009) S. L. Verdin-Terán et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn

(2009) Kristi Baker et al.   Seminars in Immunopathology

Albinterferon alfa-2b dosed every two or four weeks in interferon-naïve patients with genotype 1 chronic hepatitis C

(2008) Stefan Zeuzem et al.   HEPATOLOGY

Allergy prevention starts before conception: Maternofetal transfer of tolerance protects against the development of asthma

(2008) Tobias Polte et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

New immunosuppressive approaches: Oral administration of CD3-specific antibody to treat autoimmunity

(2008) Hirofumi Ochi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

FcRn-mediated antibody transport across epithelial cells revealed by electron tomography

(2008) Wanzhong He et al.   NATURE

Reduction of IgG in nonhuman primates by a peptide antagonist of the neonatal Fc receptor FcRn

(2008) A. R. Mezo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infused Fc-tagged  -glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice

(2008) J. H. Grubb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Podocytes use FcRn to clear IgG from the glomerular basement membrane

(2008) S. Akilesh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dependence of antibody-mediated presentation of antigen on FcRn

(2008) S.-W. Qiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+-dependent Calmodulin Binding to FcRn Affects Immunoglobulin G Transport in the Transcytotic Pathway

(2007) Bonny L. Dickinson et al.   MOLECULAR BIOLOGY OF THE CELL