Journal
JOURNAL OF CLINICAL HYPERTENSION
Volume 10, Issue 5, Pages 377-381Publisher
WILEY
DOI: 10.1111/j.1751-7176.2008.07681.x
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Funding
- European Union [IC15-CT98-0329-EPOGH, LSHM-CT-2006-037093]
- Fonds voor Wetenschappelijk Onderzoek Vlaanderen, Ministry of the Flemish Community, Brussels, Belgium [G.0424.03, G.0575.06]
- Katholieke Universiteit Leuven, Belgium [OT/99/28, OT/00/25, OT/05/49]
- Danish Heart Foundation [01-2-9-9A-22914]
- Beckett Fonden
- Lundbeck Fonden
- Ministry of Education, Culture, Sports, Science and Technology [15790293, 17790381, 18390192, 18590587]
- Ministry of Health, Labor and Welfare (Health Science Research Grants and Medical Technology Evaluation Research Grants)
- Japanese Society for the Promotion of Science [16.54041 and 18.54042]
- Japan Atherosclerosis Prevention Fund
- Uehara Memorial Foundation
- Takeda Medical Research Foundation
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Upper limits of normal ambulatory blood pressure (ABP) have been a matter of debate in recent years. Current diagnostic thresholds for ABP rely mainly on statistical parameters derived from reference populations. Recent findings from the International Database of Ambulatory Blood Pressure in Relation to Cardiovascular Outcome (IDACO) provide outcome-driven thresholds for ABP Rounded systolic/diastolic thresholds for optimal ABP were found to be 115/75 mm Hg for 24 hours, 120/80 mm Hg for daytime, and 100/65 mm Hg for nighttime. The corresponding rounded thresholds for normal ABP were 125/75 mm Hg, 130/85 mm Hg, and 110/70 mm Hg, respectively, and those for ambulatory hypertension were 130/80 mm Hg, 140/85 mm Hg, and 120/70 mm Hg. However, in clinical practice, any diagnostic threshold for blood pressure needs to be assessed in the context of the patient's overall risk profile. The IDACO database is therefore being updated with additional population cohorts to enable the construction of multifactorial risk score charts, which also include ABP. J Clin Hypertens (Greenwich). 2008;10:377-381. (C)2008 Le Jacq
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