4.4 Article

Prolonged Intrahepatic Cholestasis and Renal Failure Secondary to Anabolic Androgenic Steroid-Enriched Dietary Supplements

Journal

JOURNAL OF CLINICAL GASTROENTEROLOGY
Volume 43, Issue 7, Pages 672-675

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCG.0b013e318188be6d

Keywords

anabolic steroids; cholestasis; drug-induced liver injury; hepatotoxicity; renal toxicity; dietary supplements; nutritional supplements; jaundice; medical ethics

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The illegal enrichment of anabolic androgenic steroids in over-the-counter dietary supplements is well documented, but the health consequences have not been widely recognized. Three recent reports document cholestatic jaundice and nephropathy due to these compounds. We present 3 additional cases of anabolic androgenic steroid-enriched dietary supplement-induced hepatotoxicity and I case of renal failure. and we review the literature and the relevant features of this growing health concern. Recognition of this entity could obviate the need for invasive diagnostic testing and hospitalization and facilitate diagnosis and appropriate Counseling.

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