Article
Radiology, Nuclear Medicine & Medical Imaging
Sarah J. Menashe, Ezekiel Maloney, Francisco A. Perez, Anh-Vu Ngo, Jeff P. Otjen, Ramesh S. Iyer, Seth Friedman, Mahesh Thapa
Summary: This study aimed to establish normative data for cross sectional area (CSA) measurements of the median and ulnar nerves in children using ultrasound. The CSA measurements of the nerves were found to correlate with patient age and height.
ACADEMIC RADIOLOGY
(2022)
Review
Clinical Neurology
Anna Lena Fisse, Aristeidis H. Katsanos, Ralf Gold, Kalliopi Pitarokoili, Christos Krogias
Summary: This study conducted a systematic review and meta-analysis of CSA reference values for upper extremity nerves in healthy adults, revealing low or no heterogeneity in most nerve sites. Factors such as age, height, and weight have a positive impact on CSA values.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Review
Clinical Neurology
Sarah F. F. Eby, Masaru Teramoto, Joshua Lider, Madison Lash, Marc Caragea, Daniel M. M. Cushman
Summary: This study conducted a systematic review and meta-analysis to evaluate the normative sonographic values for adult peripheral nerve cross-sectional area (CSA). The results showed that the radial, common fibular, and tibial nerves have relatively higher CSA at specific anatomical locations. These findings provide valuable reference for clinicians and researchers studying adult peripheral nerve anatomy.
Article
Clinical Neurology
Anna Lena Fisse, Aristeidis H. Katsanos, Ralf Gold, Christos Krogias, Kalliopi Pitarokoili
Summary: The systematic review and meta-analysis of lower extremity nerves CSA reference values show differences in CSA among different regions and nerve sites, providing a basis for the development of an international standardized evaluation protocol.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Endocrinology & Metabolism
Ivana Sagova, Daniela Kantarova, Marian Mokan, Peter Vanuga
Summary: The study demonstrates a reduction in median nerve cross-sectional area 1 year after treatment of acromegaly, closely associated with decreases in IGF-I levels and lean body mass.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Govinda Adhikari, Prakash Kayastha, Sundar Suwal, Sharma Paudel, Dinesh Chataut, Santosh Maharjan, Ghanshyam Gurung
Summary: This study aimed to measure the mean cross-sectional area of the median nerve in pregnant females at different trimesters using ultrasound. Results showed variations in the nerve's size during pregnancy and differences in measurement methods. The conclusion indicated higher median nerve cross-sectional area in the third trimester.
JOURNAL OF NEPAL MEDICAL ASSOCIATION
(2021)
Article
Clinical Neurology
Jacob Horsager, Uwe Walter, Tatyana D. Fedorova, Katrine B. Andersen, Casper Skjaerbaek, Karoline Knudsen, Niels Okkels, Paul Von Weitzel-Mudersbach, Stig Eric Dyrskog, Bo Bergholt, Per Borghammer
Summary: There was no significant difference in the mean left and right vagus CSA between PD and HC groups. The right vagus CSA was significantly larger than the left in both groups. Sex-adjusted right vagus CSA was significantly smaller in the PD group, while the left vagus CSA did not show significant reduction.
FRONTIERS IN NEUROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shamrendra Narayan, Amit Goel, Ajai Kumar Singh, Anup Kumar Thacker, Neha Singh, Manish Gutch
Summary: The study aimed to evaluate CSA of peripheral nerves in patients with probable diabetic peripheral sensorimotor neuropathy. Results showed increased CSA in DPN cases compared to healthy controls, with more marked changes in the demyelinating pattern.
BRITISH JOURNAL OF RADIOLOGY
(2021)
Article
Rehabilitation
I-Te Tu, I-Ming Jou, Po-Yen Ko, Jung-Shun Lee, Li-Chieh Kuo, Chung-Yi Li, Po-Ting Wu
Summary: This study examines the ultrasonography characteristics in patients with H-CTS and evaluates the accuracy of a proposed US parameter in diagnosing H-CTS. The results indicate that RMHD might be a useful US parameter in diagnosing CTS in patients without diabetes undergoing hemodialysis.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Review
Clinical Neurology
Anna Lena Fisse, Aristeidis H. Katsanos, Ralf Gold, Kalliopi Pitarokoili, Christos Krogias
Summary: This study conducted a systematic review and meta-analysis on the CSA reference values for cervical nerve roots and vagal nerve, finding no heterogeneity in reported CSA values and no significant effects of age, gender, height, weight, and geographic continent on CSA for any of the nerve sites. The data provided can help in achieving an international standardized evaluation protocol.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Medicine, General & Internal
Mohamed Abdelmohsen Bedewi, Mamdouh Ali Kotb, Daifallah Mohammed Almalki, Ali Abdullah AlAseeri, Kholoud J. Sandougah, Ramy Abdelnaby, Steven B. Soliman, Bader A. Alhariqi, Tariq Alfaifi, Nasser M. Aldossary
Summary: The aim of this study was to use ultrasound to assess the normal cross-sectional area (CSA) of the vagus nerve (VN) in the carotid sheath. The study included 86 VNs in 43 healthy subjects, and the mean CSAs were measured for each VN. The results showed that the mean CSA of the right VN was significantly larger than the left VN. There was no significant correlation between CSA and height, weight, or age.
Article
Oncology
Cheng Xu, Yang Zhou, Zhou He, Wei Liu, Meilin Zou, Yanjun Sun, Jinxin Qiu, Yuting Ren, Guomin Mao, Yue Wang, Qinghua Xi, Yuehua Chen, Bin Zhang
Summary: This study evaluated the accuracy and effectiveness of ultrasound (US) in the diagnosis of carpal tunnel syndrome (CTS). By calculating the cross-sectional area (CSA) at the carpal tunnel and proximally at the level of the pronator quadratus muscle, it was found that Delta CSA was the most useful diagnostic index.
ANNALS OF TRANSLATIONAL MEDICINE
(2022)
Article
Biology
Lindy Trollip, Kerry Alberto, Aubrey Makgotloe
Summary: Ultrasonographic optic nerve sheath diameter (ONSD) measurement is an accurate and portable method for detecting raised intracranial pressure. This study found that the mean ONSD in healthy Black South African adults was significantly higher than that in a Canadian adult population. Age, gender, and co-morbidities were not found to significantly correlate with ONSD.
Article
Clinical Neurology
Mansoureh Mamarabadi, John A. Morren, Steven J. Shook
Summary: NMUS is a valuable adjunct for diagnosing entrapment neuropathy. Utilizing side-to-side ratios can enhance diagnostic accuracy for unilateral UNE. The M ratio and inter-E/H ratio show high diagnostic accuracy and may be useful in prospective studies for comparison with single MCSA measurement.
Article
Psychiatry
Lisa Sofie Schreiber, David Wozniak, Erik Scheller, Elise Boettcher, Johann Otto Pelz, Frank M. Schmidt
Summary: This study used high-resolution ultrasound to examine the vagus nerves in patients with major depressive disorder (MDD) and found that the cross-sectional area of the left vagus nerve was larger in MDD patients compared to healthy controls, suggesting it may be a promising imaging biomarker.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Endocrinology & Metabolism
S. Cannavo, M. Cappa, D. Ferone, A. M. Isidori, S. Loche, M. Salerno, M. Maghnie
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Orthopedics
Mattia Alessio-Mazzola, Chiara Stambazzi, Chiara Ursino, Alberto Tagliafico, Roberto Trentini, Matteo Formica
Summary: This study compared the clinical outcomes of chronic plantar fasciitis treated with ultrasound-guided platelet-rich plasma (PRP) and focal ultrasound-guided extracorporeal shockwave therapy (ESW). The results showed that both PRP and ESW were effective in treating plantar fasciitis, but PRP had lower recurrence rate and faster recovery time for athletes.
JOURNAL OF FOOT & ANKLE SURGERY
(2023)
Article
Endocrinology & Metabolism
Federico Gatto, Richard A. Feelders, Peter M. van Koetsveld, Fadime Dogan, Sebastian J. C. M. M. Neggers, Aart-Jan van der Lelij, Jessica Amaru, Diego Ferone, Leo J. Hofland
Summary: Cabergoline (CAB) is an off-label medical therapy for acromegaly, but it is overshadowed by first-generation somatostatin receptor ligands like octreotide (OCT). In this study, OCT was found to be slightly more effective than CAB in inhibiting growth hormone (GH) secretion in vitro. Additionally, the response to CAB treatment was shown to be better in GH/prolactin (PRL) co-secreting tumors.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Marta Franco, Keyvan Khorrami Chokami, Manuela Albertelli, Claudia Teti, Francesco Cocchiara, Federico Gatto, Carlo Trombetta, Diego Ferone, Mara Boschetti
Summary: This article reports a case study of a young man affected by vanishing testis syndrome (VTS) who had been followed up in our center for over 15 years. The patient received different testosterone formulations that adjusted his IGF-1 levels and growth velocity, mimicking the pubertal spurt and achieving a final height in line with his genetic target. Accurate monitoring of VTS patients and a precise reproduction of testosterone secretion during the pubertal spurt can ensure normal growth and development, leading to a high quality of life in adulthood.
BMC ENDOCRINE DISORDERS
(2023)
Article
Medicine, General & Internal
Elisa Russo, Alberto Stefano Tagliafico, Lorenzo Derchi, Bianca Bignotti, Simona Tosto, Carlo Martinoli, Alessio Signori, Francesca Brigati, Francesca Viazzi
Summary: The study aimed to investigate the role of opportunistic kidney assessment on non-enhanced chest CT in COVID-19 patients. The results showed that low RPA values and the presence of PFS independently predicted the occurrence of AKI and increased risk for mortality, respectively.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Nicole Brunetti, Massimo Calabrese, Carlo Martinoli, Alberto Stefano Tagliafico
Summary: This study assessed the current development of ultrasound-based artificial intelligence in breast cancer. The results showed that AI has excellent performance in the diagnosis, prognosis, and treatment strategy of breast cancer. However, more prospective and multicenter studies are needed to evaluate the potential impact of AI in breast ultrasound.
Editorial Material
Oncology
Alberto Stefano Tagliafico, Nehmat Houssami
Review
Oncology
Martina Dameri, Gabriella Cirmena, Francesco Ravera, Lorenzo Ferrando, Paola Cuccarolo, Mario Stabile, Giuseppe Nicolo Fanelli, Pier Vitale Nuzzo, Massimo Calabrese, Alberto Tagliafico, Alberto Ballestrero, Gabriele Zoppoli
Summary: Liquid biopsy has the potential to revolutionize clinical practice by offering a non-invasive approach for cancer diagnosis and treatment. However, the lack of standardized protocols for sample handling has hindered its implementation in clinical settings. This study provides a critical review of available standard operating procedures (SOPs) for liquid biopsy management and presents SOPs developed and utilized in a clinical trial. The aim is to address common issues and promote the adoption of interlaboratory shared protocols for optimized preanalytical handling of blood and urine samples.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2023)
Article
Sport Sciences
Alberto S. Tagliafico, Lorenzo Torri, Roberta Righetto
Summary: This study aimed to investigate the occurrence of padel tennis injuries in Liguria, Italy. A questionnaire was sent to members of the Italian Federation of Tennis who participated in official tournaments of padel tennis. The results showed that lower limb injuries were more common, with the knee being highly affected, and the elbow was the most affected area in the upper limb.
JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
(2023)
Article
Medicine, General & Internal
Daniel Alvarez Sanchez-Bayuela, Navid Ghavami, Cristina Romero Castellano, Alessandra Bigotti, Mario Badia, Lorenzo Papini, Giovanni Raspa, Gianmarco Palomba, Mohammad Ghavami, Riccardo Loretoni, Massimo Calabrese, Alberto Tagliafico, Gianluigi Tiberi
Summary: In this study, the effectiveness of the MammoWave microwave imaging device for breast cancer detection is investigated through a multicentric European clinical trial. The device uses a Huygens-principle-based radar algorithm for image reconstruction and dedicated image analysis software. Conductivity weighted microwave images are created for each breast, and various image parameters are used to quantify their non-homogenous behavior. Welch's t-test is used to verify the statistical significance between the selected image features and the gold standard radiological study review.
Article
Medicine, General & Internal
Alberto Stefano Tagliafico, Massimo Calabrese, Nicole Brunetti, Alessandro Garlaschi, Simona Tosto, Giuseppe Rescinito, Gabriele Zoppoli, Michele Piana, Cristina Campi
Summary: This study aimed to evaluate the advantages of using radiomics in the assessment of breast lesions amenable to MR-VABB. The results showed that a radiomics logistic regression model applied to DCE-MRI images increased the diagnostic accuracy compared to the standard radiological evaluation. This suggests that radiomics has the potential to reduce the number of biopsies required in suspicious breast lesions, benefiting both patients and healthcare resources.
Article
Multidisciplinary Sciences
Daniel alvarez Sanchez-Bayuela, Navid Ghavami, Gianluigi Tiberi, Lorenzo Sani, Alessandro Vispa, Alessandra Bigotti, Giovanni Raspa, Mario Badia, Lorenzo Papini, Mohammad Ghavami, Cristina Romero Castellano, Daniela Bernardi, Massimo Calabrese, Alberto Stefano Tagliafico
Summary: Microwave imaging is a safe and promising technology for breast radiology that avoids discomfort and radiation exposure. This study used a prospective clinical trial to investigate the effectiveness of a microwave imaging device in distinguishing between breasts with and without radiological findings. The results showed potential for identifying breast lesions in asymptomatic women.
Article
Radiology, Nuclear Medicine & Medical Imaging
Federico Zaottini, Riccardo Picasso, Federico Pistoia, Michelle Pansecchi, Luca Tovt, Marta Maccio, Sara Sanguinetti, Carlo Martinoli
Summary: Wrist and hand anatomy can have various clinically relevant variants affecting bones, muscles, tendons, and nerves. Understanding these abnormalities and their appearance in imaging studies is important for proper management. This review discusses the most common anatomical variants encountered in clinical practice, their embryogenesis, related syndromes, and the imaging techniques used to visualize them.
SEMINARS IN MUSCULOSKELETAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Federica Rossi, Matteo Lambertini, Nicole Brunetti, Sara De Giorgis, Maria Grazia Razeti, Massimo Calabrese, Alberto Stefano Tagliafico
Summary: The purpose of this study was to evaluate pectoralis muscle area (PMA) depletion in breast cancer patients aged 45 years or younger undergoing neoadjuvant chemotherapy (NAC) and its correlation with clinical and histopathological data. The results showed a decrease in PMA before and after NAC. However, there were no significant associations between PMA changes and other clinical and histopathological data. Therefore, assessing PMA variation on breast MRI during NAC could be a potential tool for monitoring body composition and improving outcomes in young breast cancer patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Simone Caprioli, Alberto Tagliafico, Martina Fiannacca, Fabio Borda, Riccardo Picasso, Cristina Conforti, Alessandro Casaleggio, Giuseppe Cittadini
Summary: Despite the use of antibiotics, deep neck infections remain a clinical problem with potential life-threatening complications. Imaging, particularly computed tomography, plays a crucial role in identifying the source, extent, and complications of these infections. Knowledge of neck anatomy allows radiologists to evaluate the spread of infections and communicate important information to surgeons. This review focuses on the imaging of deep neck infections, highlighting relevant anatomy and clinical scenarios to aid in prompt diagnosis and early recognition of complications.