Journal
JOURNAL OF CLINICAL ANESTHESIA
Volume 22, Issue 1, Pages 45-49Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinane.2009.06.002
Keywords
Asystole; Bradycardia; Dexmedetomidine infusion; Double lung transplantation
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The case of an 18 year-old double-lung transplant recipient recovering from acute respiratory distress syndrome who developed repeated episodes of bradycardia and asystole (maximum duration: 10 sec) during dexmedetomidine administration is presented. Increased baseline vagal tone, paroxysmal coughing spells, and opioid administration were likely contributors to the episodes. Discontinuation of the drug restored regular sinus rhythm. Double-lung transplant recipients may be at especially increased risk for this phenomenon as a result of changes in the autonomic innervation of the heart. Published by Elsevier Inc.
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