Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms

Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways

(2015) Sarah K. Baird et al.   CLINICAL & EXPERIMENTAL METASTASIS

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma

(2014) H Wang et al.   Cell Death & Disease

Over-expression of fibroblast activation protein alpha increases tumor growth in xenografts of ovarian cancer cells

(2013) L. Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Fibroblast activation protein-α promotes ovarian cancer cell proliferation and invasion via extracellular and intracellular signaling mechanisms

(2013) WeiWei Yang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells

(2013) Petra C Schuberth et al.   Journal of Translational Medicine

Interruption of mitochondrial complex IV activity and cytochrome c expression activated O2∙−-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R–PI3K–Akt and IGF-1R–PLC γ–PKC pathways

(2011) Yuan-yuan Jiang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evaluation of the tumor targeting of a FAPα-based doxorubicin prodrug

(2011) Sichao Huang et al.   JOURNAL OF DRUG TARGETING

The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin

(2010) Anamaria Brozovic et al.   CRITICAL REVIEWS IN TOXICOLOGY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma

(2009) Robert M Eager et al.   BMC CANCER

Phase II Trial of Talabostat and Docetaxel in Advanced Non-small Cell Lung Cancer

(2009) R.M. Eager et al.   CLINICAL ONCOLOGY

TGF-β-induced fibroblast activation protein expression, fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM

(2009) He Chen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

(2009) Osamu Dohi et al.   HISTOPATHOLOGY

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

(2009) A. M. LeBeau et al.   MOLECULAR CANCER THERAPEUTICS

Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model

(2009) Debbie Liao et al.   PLoS One

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Effective Immunoconjugate Therapy in Cancer Models Targeting a Serine Protease of Tumor Fibroblasts

(2008) E. Ostermann et al.   CLINICAL CANCER RESEARCH