Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 866, Issue 1-2, Pages 26-47Publisher
ELSEVIER
DOI: 10.1016/j.jchromb.2007.10.007
Keywords
systems biology; metabolomic profiling; quantitative proteomics; glycomic profiling; biodiversity; animal models; bioinformatics; stable-isotope labeling; metabolic stable-isotope labeling; LC-MS; GC-MS
Funding
- NCRR NIH HHS [P41 RR018942, P41 RR018942-01A2, RR018942] Funding Source: Medline
Ask authors/readers for more resources
This review discusses the current trends in molecular profiling for the emerging systems biology applications. Historically, the methodological developments in separation science were coincident with the availability of new ionization techniques in mass spectrometry. Coupling miniaturized separation techniques with technologically-advanced MS instrumentation and the modem data processing capabilities are at the heart of current platforms for proteomics, glycomics and metabolomics. These are being featured here by the examples from quantitative proteomics, glycan mapping and metabolomic profiling of physiological fluids. (C) 2007 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
