Article
Chemistry, Analytical
Samin Fathalinejad, Esben Taarning, Peter Christensen, Jan H. Christensen
Summary: This study developed a GC-MS identification workflow for carbohydrate fragmentation compounds, built a library of compounds detected by five different GC-MS methods, investigated and compared compound coverage among the methods, and explored possible reaction pathways for some analytes. A total of 389 compounds were detected, with solid-phase microextraction detecting the highest number of analytes and derivatization GC-MS technique detecting the lowest but largest molecules.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2021)
Article
Biochemical Research Methods
Natividad Jurado-Campos, Andres Martin-Gomez, David Saavedra, Lourdes Arce
Summary: The article highlights the potential and importance of headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) in non targeted qualitative analysis, as well as discusses a novel quality control protocol suitable for different users.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Biochemistry & Molecular Biology
Sanja Radman, Igor Jerkovic
Summary: The analysis of volatile organic compounds (VOCs) in two brown algae from the Adriatic Sea revealed differences between fresh and air-dried samples, particularly in the percentages of fatty acids and their derivatives, terpenes, and aliphatic compounds.
Article
Food Science & Technology
Jiahui Chen, Lina Tao, Ting Zhang, Jingjing Zhang, Tingting Wu, Donglei Luan, Ling Ni, Xichang Wang, Jian Zhong
Summary: This study used different techniques to analyze the effects of four thermal processing methods on the aroma profiles of acidity regulator-treated tilapia muscles, finding that thermal processing significantly and differently decreased the types of volatile organic compounds in the muscles.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Beatriz De Caroli Vizioli, Leandro Wang Hantao, Cassiana Carolina Montagner
Summary: This study developed an analytical method for detecting and quantifying nitrosamines in drinking water, with NDMA being the most frequently detected nitrosamine in the Metropolitan Region of Campinas, São Paulo, Brazil. The levels of nitrosamines found in the drinking water samples are of considerable relevance due to the area's expanded industrial and agricultural activities.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Agriculture, Multidisciplinary
Ke-ling Tu, Yu-lin Yin, Li-ming Yang, Jian-hua Wang, Qun Sun
Summary: This study aimed to improve the selection of crop seeds by predicting the germination ability of each seed, thus improving seed quality. Oxygen consumption and headspace-gas chromatography-ion mobility spectrometry were evaluated for identifying seed viability. The oxygen consumption technique showed clear differences between vital and dead seeds, and a new variable (Qt) was established for viability evaluation.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2023)
Article
Food Science & Technology
Ann-Kathrin Nedele, Raphaela Schiebelbein, Alessa Bar, Anne Kaup, Yanyan Zhang
Summary: Fermentation can significantly reduce the off-aroma concentration in soy products, as well as decrease the contribution of aldehydes, leading to a decreased perception of green and beany odors.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Ryan E. Sours, Dawit Z. Bezabeh
Summary: The described method can accurately determine ethanol content in various solid or semi-solid consumer goods and also low-alcohol liquid products. It is reliable with good reproducibility and sensitivity.
FOOD ANALYTICAL METHODS
(2021)
Review
Engineering, Environmental
Hechao Chen, Jidao Xie, Chengxiang Huang, Yining Liang, Yulin Zhang, Xiaoyan Zhao, Yuhua Ling, Lei Wang, Qi Zheng, Xiaoqiu Yang
Summary: A database of 6310 disinfection by-products (DBPs) reported between 1974 and 2022 was constructed, providing a tool for screening new DBPs, comprehensive review, and predictive model development. The study presented the origin of the collected DBPs and conducted comparative analysis on their basic information. Most DBPs remained to be identified, with acids as the main functional groups, aliphatic and aromatic compounds as the major carbon frameworks, and molecular weights ranging from 200 to 400 Da.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Pharmacology & Pharmacy
Jinjian Zheng, Christine L. Kirkpatrick, Daniel Lee, Xinxin Han, Ana I. Martinez, Kimberly Gallagher, Rebecca K. Evans, Sanjay V. Mudur, Xihui Liang, Jennifer Drake, Leah A. Buhler, Mark D. Mowery
Summary: The recent detection of potent carcinogenic nitrosamine impurities in several human medicines has highlighted the need for increased testing of nitrosamines in pharmaceutical products. In this study, a sensitive and specific analytical method for the detection of a common nitrosamine, N-nitrosodimethylamine (NDMA), in pharmaceutical products has been developed. The method has the potential to serve as a universal method for testing nitrosamines in different drug products.
Article
Environmental Sciences
Aray Zhakupbekova, Nassiba Baimatova, Elefteria Psillakis, Bulat Kenessov
Summary: A new method for quantification of unsymmetrical dimethylhydrazine transformation products in sand samples using vacuum-assisted headspace solid-phase microextraction without addition of water followed by gas chromatography-mass spectrometry is proposed. The method offers lower detection limits, better accuracy and precision, and similar or lower cost of sample preparation compared to existing methods.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Food Science & Technology
Ao Liu, Hongwei Zhang, Tongjie Liu, Pimin Gong, Yawei Wang, Hongze Wang, Xiaoying Tian, Qiqi Liu, Qingyu Cui, Xiang Xie, Lanwei Zhang, Huaxi Yi
Summary: This study investigated 46 strains of Streptococcus thermophilus isolated from commercial starter cultures and evaluated the aroma of the fermented milk produced by these strains. Different types of fermented milk were classified based on their sensory attributes, and their volatile compositions were analyzed using HS-GC-IMS and HS-SPME-GC-TOF/MS. Key compounds were identified using PCA and OPLS-DA, and these compounds could be used as indicators to develop fermented milks with specific aroma and flavor features.
Article
Biochemical Research Methods
Xu-Bo Zhang, Zhan-Bo Hu, Xin-Sheng Chai, Guang-Zhi Zhong, Xiao Ouyang, Pei-Yi Li
Summary: This paper presents a headspace gas chromatography method for determining denitrifying enzyme activity in soil samples, which demonstrates good measurement precision and reasonable accuracy, making it suitable for batch sample analysis.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Agriculture, Multidisciplinary
Wenyao Zhu, Frank Benkwitz, Bahareh Sarmadi, Paul A. Kilmartin
Summary: The new quantitative method based on SHS-GCIMS allows simultaneous quantitation of multiple aroma compounds in wine. Nonlinearity and multiple ion species were addressed using the Boltzmann function and GAM as solutions, showing desirable analytical outcomes. Potential inaccuracies were discussed, and the method was compared with GC-MS for validation and future analytical enhancement.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Medicine, Legal
Jennifer L. Berry, Mary E. Gregg, Adam J. Friss, Amanda A. Koepke, Christopher L. Suiter, Reta Newman, Megan E. Harries, Kavita M. Jeerage
Summary: Dynamic vapor microextraction (DVME) was extended to casework containers for the first time in this study, investigating the effects of different container types, oven temperatures, and collection volumes on the recovery of target compounds. The presence of polymer bag material led to losses of low-volatility species, while glass jars allowed for the recovery of target compounds across the entire volatility range.
FORENSIC SCIENCE INTERNATIONAL
(2022)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)