Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1315, Issue -, Pages 92-106Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.chroma.2013.09.031
Keywords
Chromatographic models; Rectangular pulse injections; Analytical solutions; Moment analysis; Discontinuous Galerkin method; Dynamic simulation
Funding
- Higher Education Commission (HEC) of Pakistan
Ask authors/readers for more resources
This work focuses on the analysis of two standard liquid chromatographic models, namely the lumped kinetic model and the equilibrium dispersive model. Analytical solutions, obtained by means of Laplace transformation, are derived for rectangular single solute concentration pulses of finite length and breakthrough curves injected under linear conditions. In order to analyze the solute transport behavior by means of the two models, the temporal moments up to fourth order are calculated from the Laplace-transformed solutions. The limiting cases of continuous injection and negligible mass transfer limitations are evaluated. For validation, the analytical solutions are compared with the numerical solutions of models using the discontinuous Galerkin finite element method. Results of different case studies are discussed for linear and nonlinear adsorption isotherms. The discontinuous Galerkin method is employed to obtain moments for both linear and nonlinear models numerically. Analytically and numerically determined concentration profiles and moments were found to be in good agreement. (C) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available